PMID- 30083274
OWN - NLM
STAT- MEDLINE
DCOM- 20200302
LR  - 20230928
IS  - 1838-7640 (Electronic)
IS  - 1838-7640 (Linking)
VI  - 8
IP  - 14
DP  - 2018
TI  - Microvesicles and ectosomes in angiogenesis and diabetes - message in a bottle in 
      the vascular ocean.
PG  - 3974-3976
LID - 10.7150/thno.27154 [doi]
AB  - The pathogenesis of diabetes involves dysregulated gene expression on a pre- and 
      posttranscriptional level. One key mechanism in the development and progression 
      of diabetes is thought being a dysregulation of signalling mediators such as 
      microRNAs. These microRNAs interfere with pathophysiological reactions in 
      diabetes by affecting gene transcription, insulin resistance and endothelial 
      dysfunction. Here, in this current issue, Stepien et al. analysed ectosomal miRNA 
      patterns in patients with type 2 diabetes mellitus (T2DM) using different 
      analytical techniques. The focus of the current analysis was to characterize pro- 
      and anti-angiogenic signalling effects of ectosomal miRNAs revealing important 
      pathophysiologic mechanisms and signalling in T2DM.
FAU - Lichtenauer, Michael
AU  - Lichtenauer M
AD  - Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical 
      University of Salzburg, Austria.
FAU - Jung, Christian
AU  - Jung C
AD  - Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical 
      University of Salzburg, Austria.
AD  - Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, 
      University Duesseldorf, Germany.
LA  - eng
PT  - Comment
PT  - Editorial
DEP - 20180701
PL  - Australia
TA  - Theranostics
JT  - Theranostics
JID - 101552395
RN  - 0 (MicroRNAs)
SB  - IM
CON - Theranostics. 2018 Jun 23;8(14):3874-3890. PMID: 30083267
MH  - *Cell-Derived Microparticles
MH  - *Diabetes Mellitus, Type 2
MH  - Humans
MH  - *MicroRNAs
MH  - Neovascularization, Pathologic
MH  - Oceans and Seas
PMC - PMC6071537
EDAT- 2018/08/08 06:00
MHDA- 2020/03/03 06:00
PMCR- 2018/01/01
CRDT- 2018/08/08 06:00
PHST- 2018/05/08 00:00 [received]
PHST- 2018/05/18 00:00 [accepted]
PHST- 2018/08/08 06:00 [entrez]
PHST- 2018/08/08 06:00 [pubmed]
PHST- 2020/03/03 06:00 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - thnov08p3974 [pii]
AID - 10.7150/thno.27154 [doi]
PST - epublish
SO  - Theranostics. 2018 Jul 1;8(14):3974-3976. doi: 10.7150/thno.27154. eCollection 
      2018.