PMID- 30087959
OWN - NLM
STAT- MEDLINE
DCOM- 20180905
LR  - 20181202
IS  - 1364-548X (Electronic)
IS  - 1359-7345 (Linking)
VI  - 54
IP  - 68
DP  - 2018 Aug 21
TI  - Pro-guest and acyclic cucurbit[n]uril conjugated polymers for the controlled 
      release of anti-tumor drugs.
PG  - 9486-9489
LID - 10.1039/c8cc05552a [doi]
AB  - We report "pro-guest" and acyclic cucurbit[n]uril conjugated polymers as 
      supramolecular drug delivery systems (DDSs). These supramolecular DDSs could 
      encapsulate anti-tumor drugs. Under acidic conditions, an acid-labile "pro-guest" 
      degraded to become a "competing guest", which displaced and released the 
      encapsulated drug at a tunable rate.
FAU - Jiang, Siyang
AU  - Jiang S
AD  - Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, 
      China. dama@fudan.edu.cn.
FAU - Lan, Shang
AU  - Lan S
FAU - Mao, Dake
AU  - Mao D
FAU - Yang, Xuan
AU  - Yang X
FAU - Shi, Kejia
AU  - Shi K
FAU - Ma, Da
AU  - Ma D
LA  - eng
PT  - Journal Article
PL  - England
TA  - Chem Commun (Camb)
JT  - Chemical communications (Cambridge, England)
JID - 9610838
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Bridged-Ring Compounds)
RN  - 0 (Drug Carriers)
RN  - 0 (Fluorescent Dyes)
RN  - 0 (Imidazoles)
RN  - 0 (Polymers)
RN  - 0I8Y3P32UF (Berberine)
RN  - 7673326042 (Irinotecan)
RN  - 7M7YKX2N15 (Topotecan)
RN  - 80168379AG (Doxorubicin)
RN  - BZ114NVM5P (Mitoxantrone)
RN  - XT3Z54Z28A (Camptothecin)
SB  - IM
MH  - Antineoplastic Agents/*chemistry/metabolism
MH  - Berberine/chemistry
MH  - Bridged-Ring Compounds/chemical synthesis/*chemistry/metabolism
MH  - Camptothecin/analogs & derivatives/chemistry/metabolism
MH  - Doxorubicin/chemistry/metabolism
MH  - Drug Carriers/chemical synthesis/*chemistry/metabolism
MH  - Drug Liberation
MH  - Fluorescent Dyes/chemistry
MH  - HeLa Cells
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Imidazoles/chemical synthesis/*chemistry/metabolism
MH  - Irinotecan
MH  - Mitoxantrone/chemistry/metabolism
MH  - Polymers/chemical synthesis/*chemistry/metabolism
MH  - Topotecan/chemistry/metabolism
EDAT- 2018/08/09 06:00
MHDA- 2018/09/06 06:00
CRDT- 2018/08/09 06:00
PHST- 2018/08/09 06:00 [pubmed]
PHST- 2018/09/06 06:00 [medline]
PHST- 2018/08/09 06:00 [entrez]
AID - 10.1039/c8cc05552a [doi]
PST - ppublish
SO  - Chem Commun (Camb). 2018 Aug 21;54(68):9486-9489. doi: 10.1039/c8cc05552a.