PMID- 30091323
OWN - NLM
STAT- MEDLINE
DCOM- 20180831
LR  - 20181202
IS  - 1976-2437 (Electronic)
IS  - 0513-5796 (Print)
IS  - 0513-5796 (Linking)
VI  - 59
IP  - 7
DP  - 2018 Sep
TI  - Diagnostic Ability of Swept-Source and Spectral-Domain Optical Coherence 
      Tomography for Glaucoma.
PG  - 887-896
LID - 10.3349/ymj.2018.59.7.887 [doi]
AB  - PURPOSE: To compare the diagnostic abilities of swept-source optical coherence 
      tomography (OCT) [Deep Range Imaging OCT-1 (DRI-OCT)] and spectral-domain OCT 
      (Cirrus HD-OCT) for glaucoma in Korean adults. MATERIALS AND METHODS: This 
      retrospective study involved measuring peripapillary retinal nerve fiber layer 
      (PP-RNFL) thickness, full macular thickness, and ganglion cell-inner plexiform 
      layer (GC-IPL) thickness on two different OCT systems. We used three-dimensional 
      optic disc scanning of DRI-OCT and included 12 clock-hour sectors for measurement 
      of the PP-RNFL. Areas under receiver operating characteristic curves (AUCs) were 
      calculated and compared to determine how well each system could distinguish 
      control and glaucomatous patients. RESULTS: Ninety-one healthy and 58 
      glaucomatous eyes were included. Both systems could clearly distinguish between 
      control eyes and eyes with moderate to severe glaucoma. Among all sectors, the 
      AUC values of areas associated with glaucoma were >0.7 for both OCTs. The PP-RNFL 
      sector of highest AUC value on both OCTs was the inferior sector of the 
      clock-hour map (0.968 and 0.959 in DRI-OCT and Cirrus HD-OCT, respectively). 
      Among macular thickness sectors, AUC values were highest on both OCTs for the 
      outer inferior sector (0.859 and 0.853 in DRI-OCT and Cirrus HD-OCT, 
      respectively). The GC-IPL also provided high diagnostic values (DRI-OCT and 
      Cirrus HD-OCT were the best in the average and inferior sectors, respectively). 
      CONCLUSION: Although the two OCT systems provided different thickness 
      measurements, DRI-OCT exhibited as good, if not better, diagnostic ability for 
      glaucoma as Cirrus HD-OCT in Korean adults.
CI  - (c) Copyright: Yonsei University College of Medicine 2018.
FAU - Lee, Sang Yeop
AU  - Lee SY
AD  - Department of Ophthalmology, Severance Hospital, Institute of Vision Research, 
      Yonsei University College of Medicine, Seoul, Korea.
FAU - Bae, Hyoung Won
AU  - Bae HW
AD  - Department of Ophthalmology, Severance Hospital, Institute of Vision Research, 
      Yonsei University College of Medicine, Seoul, Korea.
FAU - Seong, Gong Je
AU  - Seong GJ
AD  - Department of Ophthalmology, Severance Hospital, Institute of Vision Research, 
      Yonsei University College of Medicine, Seoul, Korea.
FAU - Kim, Chan Yun
AU  - Kim CY
AUID- ORCID: 0000-0002-8373-9999
AD  - Department of Ophthalmology, Severance Hospital, Institute of Vision Research, 
      Yonsei University College of Medicine, Seoul, Korea. kcyeye@yuhs.ac.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - Yonsei Med J
JT  - Yonsei medical journal
JID - 0414003
SB  - IM
MH  - Adult
MH  - Aged
MH  - Area Under Curve
MH  - Case-Control Studies
MH  - Female
MH  - Glaucoma/*diagnosis
MH  - Humans
MH  - Intraocular Pressure/physiology
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/*pathology
MH  - Optic Disk/*pathology
MH  - Predictive Value of Tests
MH  - ROC Curve
MH  - Reproducibility of Results
MH  - Republic of Korea
MH  - Retinal Ganglion Cells/*pathology
MH  - Retrospective Studies
MH  - Sensitivity and Specificity
MH  - Tomography, Optical Coherence/*methods
PMC - PMC6082988
OTO - NOTNLM
OT  - Glaucoma
OT  - diagnostic ability
OT  - spectral domain optical coherence tomography
OT  - swept source optical coherence tomography
COIS- The authors have no financial conflicts of interest.
EDAT- 2018/08/10 06:00
MHDA- 2018/09/01 06:00
PMCR- 2018/09/01
CRDT- 2018/08/10 06:00
PHST- 2018/03/22 00:00 [received]
PHST- 2018/06/25 00:00 [revised]
PHST- 2018/07/03 00:00 [accepted]
PHST- 2018/08/10 06:00 [entrez]
PHST- 2018/08/10 06:00 [pubmed]
PHST- 2018/09/01 06:00 [medline]
PHST- 2018/09/01 00:00 [pmc-release]
AID - 59.887 [pii]
AID - 10.3349/ymj.2018.59.7.887 [doi]
PST - ppublish
SO  - Yonsei Med J. 2018 Sep;59(7):887-896. doi: 10.3349/ymj.2018.59.7.887.