PMID- 30094728
OWN - NLM
STAT- MEDLINE
DCOM- 20190315
LR  - 20200225
IS  - 1433-7339 (Electronic)
IS  - 0941-4355 (Linking)
VI  - 27
IP  - 3
DP  - 2019 Mar
TI  - Physical activity and associations with treatment-induced adverse effects among 
      prostate cancer patients.
PG  - 1001-1011
LID - 10.1007/s00520-018-4389-5 [doi]
AB  - PURPOSE: The present study aimed to determine the level of physical activity (PA) 
      among prostate cancer (PCa) patients across treatment modalities and explore the 
      association between PA and treatment-induced adverse effects (AEs). METHODS: The 
      present study was based on a cross-sectional postal survey among members of the 
      Norwegian Prostate Cancer Association. Patients were eligible for the present 
      study if they had either (1) completed radical prostatectomy, (2) completed 
      radiotherapy and (neo)-adjuvant androgen deprivation therapy (ADT), or (3) were 
      undergoing lifelong ADT. Adverse effects were measured by the Expanded Prostate 
      Cancer Index Composite for Clinical Practice. RESULTS: In total, 696 patients 
      were included. There was no statistically significant difference in level of PA 
      across treatment modalities. Bowel symptoms mainly related to radiotherapy 
      decreased the odds of exercising >/= 2 times per week, along with age >/= 70 years, 
      participation in the workforce, and BMI >/= 25 kg/m(2). Among patients who were 
      undergoing ADT, 5 years or more since diagnosis reduced the odds of exercising 
      >/= 2 times per week by almost 60%. CONCLUSION: The level of PA did not differ 
      across PCa patients treated with different modalities. Increasing bowel symptoms 
      reduced the likelihood of exercising >/= 2 times per week. PCa patients should be 
      educated about possible treatment-induced AEs affecting PA level, enabling them 
      to counteract the development of physical inactivity.
FAU - Bohn, Synne-Kristin Hoffart
AU  - Bohn SH
AUID- ORCID: 0000-0001-7469-7777
AD  - National Advisory Unit on Late Effects after Cancer Treatment, Department of 
      Oncology, Oslo University Hospital , Oslo, Norway. synn@ous-hf.no.
FAU - Fossa, Sophie Dorothea
AU  - Fossa SD
AD  - National Advisory Unit on Late Effects after Cancer Treatment, Department of 
      Oncology, Oslo University Hospital , Oslo, Norway.
AD  - Faculty of Medicine, University of Oslo, Oslo, Norway.
FAU - Wisloff, Torbjorn
AU  - Wisloff T
AD  - Department of Infectious Disease Epidemiology and Modelling, Norwegian Institute 
      of Public Health, and Department of Health Management and Health Economics, 
      University of Oslo, Oslo, Norway.
FAU - Thorsen, Lene
AU  - Thorsen L
AD  - National Advisory Unit on Late Effects after Cancer Treatment, Department of 
      Oncology, Oslo University Hospital , Oslo, Norway.
AD  - Department of Clinical Service, Oslo University Hospital, Oslo, Norway.
LA  - eng
GR  - 45980/Kreftforeningen/
PT  - Journal Article
DEP - 20180809
PL  - Germany
TA  - Support Care Cancer
JT  - Supportive care in cancer : official journal of the Multinational Association of 
      Supportive Care in Cancer
JID - 9302957
RN  - 0 (Androgen Antagonists)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Androgen Antagonists/adverse effects
MH  - Combined Modality Therapy/*adverse effects
MH  - Cross-Sectional Studies
MH  - *Exercise
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prostatectomy/*adverse effects
MH  - Prostatic Neoplasms/*therapy
OTO - NOTNLM
OT  - Androgen deprivation therapy
OT  - Physical activity
OT  - Prostate cancer
OT  - Prostatectomy
OT  - Radiotherapy
OT  - Treatment-induced adverse effects
EDAT- 2018/08/11 06:00
MHDA- 2019/03/16 06:00
CRDT- 2018/08/11 06:00
PHST- 2018/03/28 00:00 [received]
PHST- 2018/07/31 00:00 [accepted]
PHST- 2018/08/11 06:00 [pubmed]
PHST- 2019/03/16 06:00 [medline]
PHST- 2018/08/11 06:00 [entrez]
AID - 10.1007/s00520-018-4389-5 [pii]
AID - 10.1007/s00520-018-4389-5 [doi]
PST - ppublish
SO  - Support Care Cancer. 2019 Mar;27(3):1001-1011. doi: 10.1007/s00520-018-4389-5. 
      Epub 2018 Aug 9.