PMID- 30094784
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230918
IS  - 1869-6953 (Print)
IS  - 1869-6961 (Electronic)
IS  - 1869-6961 (Linking)
VI  - 9
IP  - 5
DP  - 2018 Oct
TI  - Current Level of Glycemic Control and Clinical Inertia in Subjects Using Insulin 
      for the Treatment of Type 1 and Type 2 Diabetes in the Czech Republic and the 
      Slovak Republic: Results of a Multinational, Multicenter, Observational Survey 
      (DIAINFORM).
PG  - 1897-1906
LID - 10.1007/s13300-018-0485-2 [doi]
AB  - INTRODUCTION: The aim of the study was to determine the level of metabolic 
      control in type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) 
      patients in the Czech and Slovak Republics. METHODS: A non-interventional 
      prospective (observational) study was conducted from January 2015 until April 
      2016 in routine clinical practice settings at 141 centers in the Czech and Slovak 
      Republics. Data were analyzed from a total of 425 patients with T1DM and 1034 
      patients with T2DM, proportionally corresponding to the number of patients in 
      both countries. The primary objective of the study was to determine the 
      percentage of patients with HbA1c < 7% (53 mmol/mol). RESULTS: Patients with 
      T1DM: In this group of patients (55.8% males, mean age 45.9 +/- 14.83 years, BMI 
      25.8 +/- 4.21 kg/m(2), diabetes duration 12.1 +/- 9.44 years), 29.9% reached HbA1c 
      levels < 53 mmol/mol. Patients with T2DM: In this group of patients (50.3% male, 
      mean age 63.9 +/- 9.65 years, BMI 31.0 +/- 5.19 kg/m(2), diabetes duration 
      12.4 +/- 7.47 years, duration of insulin therapy 5.8 +/- 4.71 years), 33.4% reached 
      HbA1c levels < 53 mmol/mol. CONCLUSION: The overall percentage of patients with 
      HbA1c < 53 mmol/mol in the T1DM group was 29.9% and in the T2DM group was 33.4%. 
      Despite an increasing number of treatment options, most patients still fail to 
      reach the recommended HbA1c targets. FUNDING: Sanofi, Czech Republic.
FAU - Broz, Jan
AU  - Broz J
AUID- ORCID: 0000-0003-2465-7333
AD  - Department of Internal Medicine, Second Faculty of Medicine, Charles University, 
      Prague, Prague, Czech Republic. zorb@seznam.cz.
FAU - Janickova Zdarska, Denisa
AU  - Janickova Zdarska D
AD  - Department of Internal Medicine, Second Faculty of Medicine, Charles University, 
      Prague, Prague, Czech Republic.
FAU - Urbanova, Jana
AU  - Urbanova J
AD  - Center for Research in Diabetes, Metabolism and Nutrition, 2nd Department of 
      Internal Medicine, Third Faculty of Medicine, Charles University, Prague, Czech 
      Republic.
FAU - Brabec, Marek
AU  - Brabec M
AD  - Institute of Computer Science of the ASCR, v.v.i., Prague, Czech Republic.
AD  - Czech Institute of Informatics, Robotics, and Cybernetics, Czech Technical in 
      University, Prague, Czech Republic.
FAU - Donicova, Viera
AU  - Donicova V
AD  - Private Department of Diabetology Internal Medicine and Metabolism, Kosice, 
      Slovakia.
FAU - Stepanova, Radka
AU  - Stepanova R
AD  - Aprova sro, Brno, Czech Republic.
FAU - Martinka, Emil
AU  - Martinka E
AD  - National Institute of Endocrinology and Diabetology, Lubochna, Slovakia.
FAU - Kvapil, Milan
AU  - Kvapil M
AD  - Department of Internal Medicine, Second Faculty of Medicine, Charles University, 
      Prague, Prague, Czech Republic.
LA  - eng
GR  - N/A/Sanofi Czech Republic/
PT  - Journal Article
DEP - 20180809
PL  - United States
TA  - Diabetes Ther
JT  - Diabetes therapy : research, treatment and education of diabetes and related 
      disorders
JID - 101539025
PMC - PMC6167301
OTO - NOTNLM
OT  - Clinical inertia
OT  - HbA1c
OT  - Insulin therapy
OT  - Metabolic control
OT  - Type 1 diabetes
OT  - Type 2 diabetes
EDAT- 2018/08/11 06:00
MHDA- 2018/08/11 06:01
PMCR- 2018/08/09
CRDT- 2018/08/11 06:00
PHST- 2018/05/28 00:00 [received]
PHST- 2018/08/11 06:00 [pubmed]
PHST- 2018/08/11 06:01 [medline]
PHST- 2018/08/11 06:00 [entrez]
PHST- 2018/08/09 00:00 [pmc-release]
AID - 10.1007/s13300-018-0485-2 [pii]
AID - 485 [pii]
AID - 10.1007/s13300-018-0485-2 [doi]
PST - ppublish
SO  - Diabetes Ther. 2018 Oct;9(5):1897-1906. doi: 10.1007/s13300-018-0485-2. Epub 2018 
      Aug 9.