PMID- 3009530
OWN - NLM
STAT- MEDLINE
DCOM- 19860530
LR  - 20210526
IS  - 0095-1137 (Print)
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Linking)
VI  - 23
IP  - 2
DP  - 1986 Feb
TI  - Quantitative estimation by a standardized enzyme-linked immunosorbent assay of 
      human T-cell lymphotropic virus type I antibodies in adult T-cell leukemia and 
      acquired immune deficiency syndrome.
PG  - 212-6
AB  - Sera from patients with adult T-cell leukemia and asymptomatic carriers of human 
      T-cell lymphotropic virus type I (HTLV-I) from widely separated areas of the 
      world reacted strongly in a standardized quantitative enzyme-linked immunosorbent 
      assay procedure with HTLV-I viral antigen prepared from a strain isolated in the 
      United States. There was a sharp differentiation of the values seen in the 
      patients as compared with a normal population. Of the 35 acquired immune 
      deficiency syndrome patients with Kaposi's sarcoma, only 2 were positive for 
      HTLV-I antibodies in this test, and the distribution of the negative assay values 
      in the other acquired immune deficiency syndrome patient sera was similar to that 
      seen in the normal sera. Sera which contained extremely high levels of antibodies 
      to other unrelated viruses (rubella virus, cytomegalovirus, and herpes simplex 
      virus) all showed negative anti-HTLV-I results, in a pattern similar to the 
      normal sera. Sera from patients with several autoimmune disease (systemic lupus 
      erythematosus, rheumatoid arthritis, thyroiditis) as well as those with 
      infectious mononucleosis or myeloma all also showed the normal distribution of 
      negative results, in spite of the presence of very high levels of the 
      autoantibodies, etc., associated with their illnesses.
FAU - Halbert, S P
AU  - Halbert SP
FAU - Poiesz, B
AU  - Poiesz B
FAU - Friedman-Kien, A E
AU  - Friedman-Kien AE
FAU - Montagna, R
AU  - Montagna R
FAU - Blattner, W A
AU  - Blattner WA
FAU - Anken, M
AU  - Anken M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antibodies, Viral)
RN  - 0 (Antigens, Viral)
RN  - 0 (Autoantibodies)
RN  - 0 (HIV Antibodies)
RN  - 0 (HIV Antigens)
SB  - IM
MH  - Acquired Immunodeficiency Syndrome/*immunology
MH  - Adult
MH  - Aged
MH  - Antibodies, Viral/*analysis/immunology
MH  - Antigens, Viral/immunology
MH  - Autoantibodies/analysis
MH  - Autoimmune Diseases/immunology
MH  - Carrier State/immunology
MH  - Deltaretrovirus/*immunology
MH  - Dominican Republic
MH  - Enzyme-Linked Immunosorbent Assay
MH  - HIV Antibodies
MH  - HIV Antigens
MH  - Humans
MH  - Jamaica
MH  - Japan
MH  - Leukemia/*immunology
MH  - Middle Aged
MH  - T-Lymphocytes
MH  - United States
PMC - PMC268614
OID - PIP: 057828
OID - POP: 00193753
OTO - PIP
OT  - *Acquired Immunodeficiency Syndrome
OT  - Americas
OT  - *Antibodies--analysis
OT  - Biology
OT  - Developed Countries
OT  - Diseases
OT  - Examinations And Diagnoses
OT  - Florida
OT  - *Hematological Effects
OT  - Hemic System
OT  - Hiv Infections
OT  - Immunity
OT  - Immunologic Factors
OT  - *Laboratory Examinations And Diagnoses
OT  - North America
OT  - Northern America
OT  - Physiology
OT  - United States
OT  - Viral Diseases
EDAT- 1986/02/01 00:00
MHDA- 1986/02/01 00:01
PMCR- 1986/02/01
CRDT- 1986/02/01 00:00
PHST- 1986/02/01 00:00 [pubmed]
PHST- 1986/02/01 00:01 [medline]
PHST- 1986/02/01 00:00 [entrez]
PHST- 1986/02/01 00:00 [pmc-release]
AID - 10.1128/jcm.23.2.212-216.1986 [doi]
PST - ppublish
SO  - J Clin Microbiol. 1986 Feb;23(2):212-6. doi: 10.1128/jcm.23.2.212-216.1986.