PMID- 30098510 OWN - NLM STAT- MEDLINE DCOM- 20181211 LR - 20181211 IS - 1090-2414 (Electronic) IS - 0147-6513 (Linking) VI - 164 DP - 2018 Nov 30 TI - Complex effects of pollution on fish in major rivers in the Czech Republic. PG - 92-99 LID - S0147-6513(18)30716-4 [pii] LID - 10.1016/j.ecoenv.2018.07.109 [doi] AB - Monitoring the contamination level in aquatic environments and assessing the impact on aquatic life occurs throughout the world. In the present study, an approach based on a combination of biomarkers and the distribution of various industrial and municipal pollutants was used to investigate the effect of aquatic environmental contamination on fish. Monitoring was performed in ten rivers in the Czech Republic (Berounka, Dyje, Elbe, Luznice, Odra, Ohre, Otava, Sazava, Svratka, and Vltava rivers, with one or two locations in each river) at the same sites that were regularly monitored within the Czech National Monitoring Program in 2007-2011. Health status, hepatic ethoxyresorufin-O-deethylase (EROD) activity, total cytochrome P450 content, and the plasma vitellogenin concentration were assessed in wild chub (Squalius cephalus) males caught at the monitored sites. The contamination level was the highest in the Svratka River downstream of Brno. Among all measured persistent organic pollutants (POPs), polychlorinated biphenyls and dichlorodiphenyltrichloroethane and its metabolites were the major contributors of POPs in fish muscle. Elbe, Odra, and Svratka rivers were identified as the most polluted. Fish from these locations showed reduced gonad size, increased vitellogenin concentration in male plasma, EROD, and total cytochrome P450 content. These biomarkers can be used for future environmental monitoring assessments. Overall, this study improves our understanding of the relationship between human activities and pollutant loads and further contributes to the decision to support local watershed managers to protect water quality in this region. CI - Copyright (c) 2018 Elsevier Inc. All rights reserved. FAU - Burkina, Viktoriia AU - Burkina V AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: vburkina@frov.jcu.cz. FAU - Zamaratskaia, Galia AU - Zamaratskaia G AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic; Swedish University of Agricultural Sciences, Uppsala BioCenter, Department of Molecular Science, P.O. Box 7015, SE-750 07 Uppsala, Sweden. Electronic address: Galia.Zamaratskaia@slu.se. FAU - Sakalli, Sidika AU - Sakalli S AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: sakalli@frov.jcu.cz. FAU - Giang, Pham Thai AU - Giang PT AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: phamthai@frov.jcu.cz. FAU - Kodes, Vit AU - Kodes V AD - Czech Hydrometeorological Institute, Section of Water Quality, Na Sabatce 17, CZ-14306 Prague 4, Czech Republic. Electronic address: kodes@chmi.cz. FAU - Grabic, Roman AU - Grabic R AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: rgrabic@frov.jcu.cz. FAU - Velisek, Josef AU - Velisek J AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: velisek@frov.jcu.cz. FAU - Turek, Jan AU - Turek J AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: turek@frov.jcu.cz. FAU - Kolarova, Jitka AU - Kolarova J AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: kolarova@frov.jcu.cz. FAU - Zlabek, Vladimir AU - Zlabek V AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: vzlabek@frov.jcu.cz. FAU - Randak, Tomas AU - Randak T AD - University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, 389 25 Vodnany, Czech Republic. Electronic address: trandak@frov.jcu.cz. LA - eng PT - Journal Article DEP - 20180808 PL - Netherlands TA - Ecotoxicol Environ Saf JT - Ecotoxicology and environmental safety JID - 7805381 RN - 0 (Biomarkers) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Vitellogenins) RN - 0 (Water Pollutants, Chemical) RN - 9035-51-2 (Cytochrome P-450 Enzyme System) RN - CIW5S16655 (DDT) RN - DFC2HB4I0K (Polychlorinated Biphenyls) RN - EC 1.14.14.1 (Cytochrome P-450 CYP1A1) SB - IM MH - Animals MH - Biomarkers/metabolism MH - *Cyprinidae MH - Cytochrome P-450 CYP1A1/metabolism MH - Cytochrome P-450 Enzyme System/metabolism MH - Czech Republic MH - DDT/analysis MH - *Environmental Monitoring MH - Environmental Pollution MH - Fishes/metabolism MH - Hydrocarbons, Chlorinated/analysis MH - Liver/drug effects/metabolism MH - Male MH - Polychlorinated Biphenyls/analysis MH - Principal Component Analysis MH - Rivers/*chemistry MH - Vitellogenins/blood MH - Water Pollutants, Chemical/*analysis MH - Water Quality OTO - NOTNLM OT - Biomarker OT - Biomonitoring OT - Chub OT - EROD OT - Passive sampling OT - Vitellogenin EDAT- 2018/08/12 06:00 MHDA- 2018/12/12 06:00 CRDT- 2018/08/12 06:00 PHST- 2018/04/12 00:00 [received] PHST- 2018/07/23 00:00 [revised] PHST- 2018/07/26 00:00 [accepted] PHST- 2018/08/12 06:00 [pubmed] PHST- 2018/12/12 06:00 [medline] PHST- 2018/08/12 06:00 [entrez] AID - S0147-6513(18)30716-4 [pii] AID - 10.1016/j.ecoenv.2018.07.109 [doi] PST - ppublish SO - Ecotoxicol Environ Saf. 2018 Nov 30;164:92-99. doi: 10.1016/j.ecoenv.2018.07.109. Epub 2018 Aug 8.