PMID- 3009873
OWN - NLM
STAT- MEDLINE
DCOM- 19860527
LR  - 20200724
IS  - 0022-538X (Print)
IS  - 1098-5514 (Electronic)
IS  - 0022-538X (Linking)
VI  - 58
IP  - 2
DP  - 1986 May
TI  - Mammary tumorigenesis in feral Mus cervicolor popaeus.
PG  - 619-25
AB  - A pedigreed breeding population of feral Mus cervicolor popaeus with a high 
      incidence of mammary tumors, arising between 6 and 14 months of age, is 
      described. These mice were chronically infected with a type B retrovirus which is 
      distantly related to the mouse mammary tumor virus (MMTV) of inbred strains of 
      Mus musculus. MMTV-induced mammary tumors in inbred mice frequently (80%) 
      contained an insertion of the viral genome into the int-1 or int-2 loci of the 
      tumor cellular genome. These two cellular genetic loci were also altered by viral 
      insertion in 11 of 20 M. cervicolor popaeus mammary tumor cellular DNAs tested. 
      Results of our study of mammary tumorigenesis in feral mice demonstrate that 
      viral-induced rearrangement and activation of the int loci are not limited to the 
      genetic background of inbred mice selected for highly infectious MMTV and a high 
      incidence of mammary tumors.
FAU - Escot, C
AU  - Escot C
FAU - Hogg, E
AU  - Hogg E
FAU - Callahan, R
AU  - Callahan R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Virol
JT  - Journal of virology
JID - 0113724
RN  - 0 (DNA, Neoplasm)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Animals
MH  - DNA/analysis/genetics
MH  - DNA, Neoplasm/analysis/genetics
MH  - Genes
MH  - *Genes, Viral
MH  - Liver/analysis
MH  - Mammary Neoplasms, Experimental/genetics/*microbiology
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Muridae/*microbiology
MH  - *Recombination, Genetic
PMC - PMC252952
EDAT- 1986/05/01 00:00
MHDA- 1986/05/01 00:01
PMCR- 1986/05/01
CRDT- 1986/05/01 00:00
PHST- 1986/05/01 00:00 [pubmed]
PHST- 1986/05/01 00:01 [medline]
PHST- 1986/05/01 00:00 [entrez]
PHST- 1986/05/01 00:00 [pmc-release]
AID - 10.1128/JVI.58.2.619-625.1986 [doi]
PST - ppublish
SO  - J Virol. 1986 May;58(2):619-25. doi: 10.1128/JVI.58.2.619-625.1986.