PMID- 30100760
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240329
IS  - 1179-1349 (Print)
IS  - 1179-1349 (Electronic)
IS  - 1179-1349 (Linking)
VI  - 10
DP  - 2018
TI  - Cross-national health care database utilization between Spain and France: results 
      from the EPICHRONIC study assessing the prevalence of type 2 diabetes mellitus.
PG  - 863-874
LID - 10.2147/CLEP.S151890 [doi]
AB  - AIM: The EPICHRONIC (EPIdemiology of CHRONIC diseases) project investigated the 
      possibility of developing common procedures for French and Spanish electronic 
      health care databases to enable large-scale pharmacoepidemiological studies on 
      chronic diseases. A feasibility study assessed the prevalence of type 2 diabetes 
      mellitus (T2DM) in Navarre and the Basque Country (Spain) and the Midi-Pyrenees 
      region (France). PATIENTS AND METHODS: We described and compared database 
      structures and the availability of hospital, outpatient, and drug-dispensing data 
      from 5.9 million inhabitants. Due to differences in database structures and 
      recorded data, we could not develop a common procedure to estimate T2DM 
      prevalence, but identified an algorithm specific to each database. Patients were 
      identified using primary care diagnosis codes previously validated in Spanish 
      databases and a combination of primary care diagnosis codes, hospital diagnosis 
      codes, and data on exposure to oral antidiabetic drugs from the French database. 
      RESULTS: Spanish and French databases (the latter termed Systeme National 
      d'Information Inter-Regimes de l'Assurance Maladie [SNIIRAM]) included 
      demographic, primary care diagnoses, hospital diagnoses, and outpatient 
      drug-dispensing data. Diagnoses were encoded using the International 
      Classification of Primary Care (version 2) and the International Classification 
      of Diseases, version 9 and version 10 (ICD-9 and ICD-10) in the Spanish 
      databases, whereas the SNIIRAM contained ICD-10 codes. All data were anonymized 
      before transferring to researchers. T2DM prevalence in the population over 20 
      years was estimated to be 6.6-7.0% in the Spanish regions and 6.3% in the 
      Midi-Pyrenees region with ~2% higher estimates for males in the three regions. 
      CONCLUSION: Tailored procedures can be designed to estimate the prevalence of 
      T2DM in population-based studies from Spanish and French electronic health care 
      records.
FAU - Moulis, Guillaume
AU  - Moulis G
AD  - Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - UMR1027 INSERM, University of Toulouse, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - Clinical Investigation Center 1436, Toulouse University Hospital, Toulouse, 
      France, moulis.g@chu-toulouse.fr.
FAU - Ibanez, Berta
AU  - Ibanez B
AD  - Navarrabiomed, Health Department, Public University of Navarra, Pamplona, Spain.
AD  - IdiSNA, Pamplona, Spain.
AD  - Health Service Research on Chronic Patients Network (REDISSEC), Pamplona, Spain.
FAU - Palmaro, Aurore
AU  - Palmaro A
AD  - UMR1027 INSERM, University of Toulouse, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - Clinical Investigation Center 1436, Toulouse University Hospital, Toulouse, 
      France, moulis.g@chu-toulouse.fr.
FAU - Aizpuru, Felipe
AU  - Aizpuru F
AD  - Health Service Research on Chronic Patients Network (REDISSEC), Pamplona, Spain.
AD  - Research Unit Araba (BioAraba), Osakidetza-Basque Health Department, 
      Vitoria-Gasteiz, Spain.
AD  - Healthcare Services Sub-directorate, Osakidetza-Basque Health Service, Araba, 
      Spain.
FAU - Millan, Eduardo
AU  - Millan E
AD  - Health Service Research on Chronic Patients Network (REDISSEC), Pamplona, Spain.
AD  - Healthcare Services Sub-directorate, Osakidetza-Basque Health Service, Araba, 
      Spain.
FAU - Lapeyre-Mestre, Maryse
AU  - Lapeyre-Mestre M
AD  - UMR1027 INSERM, University of Toulouse, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - Clinical Investigation Center 1436, Toulouse University Hospital, Toulouse, 
      France, moulis.g@chu-toulouse.fr.
AD  - Department of Medical and Clinical Pharmacology, Toulouse University Hospital, 
      Toulouse, France.
FAU - Sailler, Laurent
AU  - Sailler L
AD  - Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - UMR1027 INSERM, University of Toulouse, Toulouse, France, 
      moulis.g@chu-toulouse.fr.
AD  - Clinical Investigation Center 1436, Toulouse University Hospital, Toulouse, 
      France, moulis.g@chu-toulouse.fr.
FAU - Cambra, Koldo
AU  - Cambra K
AD  - IdiSNA, Pamplona, Spain.
AD  - Health Service Research on Chronic Patients Network (REDISSEC), Pamplona, Spain.
AD  - Institute of Public Health and Labour Health of Navarra, Pamplona, Spain.
LA  - eng
PT  - Journal Article
DEP - 20180727
PL  - New Zealand
TA  - Clin Epidemiol
JT  - Clinical epidemiology
JID - 101531700
PMC - PMC6067780
OTO - NOTNLM
OT  - cross-national study
OT  - electronic health care database
OT  - epidemiology
OT  - pharmacoepidemiology
OT  - population-based study
OT  - type 2 diabetes mellitus
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2018/08/14 06:00
MHDA- 2018/08/14 06:01
PMCR- 2018/07/27
CRDT- 2018/08/14 06:00
PHST- 2018/08/14 06:00 [entrez]
PHST- 2018/08/14 06:00 [pubmed]
PHST- 2018/08/14 06:01 [medline]
PHST- 2018/07/27 00:00 [pmc-release]
AID - clep-10-863 [pii]
AID - 10.2147/CLEP.S151890 [doi]
PST - epublish
SO  - Clin Epidemiol. 2018 Jul 27;10:863-874. doi: 10.2147/CLEP.S151890. eCollection 
      2018.