PMID- 30101391
OWN - NLM
STAT- MEDLINE
DCOM- 20190919
LR  - 20190919
IS  - 0942-0940 (Electronic)
IS  - 0001-6268 (Linking)
VI  - 160
IP  - 10
DP  - 2018 Oct
TI  - Vascular responses to abrupt blood flow change after bypass surgery for complex 
      intracranial aneurysms.
PG  - 1945-1953
LID - 10.1007/s00701-018-3653-2 [doi]
AB  - BACKGROUND: Bypass surgery for complex intracranial aneurysms (IAs) results in 
      drastic blood flow changes in intracranial arteries. The aim of the study was to 
      elucidate how vessels adapt to blood flow changes after bypass surgery with 
      phase-contrast magnetic resonance imaging (PC-MRI). METHODS: This is a 
      prospective observational study to assess changes of the blood flow in 
      intracranial arteries after bypass surgery for IAs. Flow rates and vessel 
      diameters were measured with PC-MRI in 52 intracranial arteries of 7 healthy 
      volunteers and 31 arteries of 8 IA patients who underwent bypass surgery. Wall 
      shear stress (WSS) was calculated with the Hagen-Poiseuille formula. In 18 
      arteries of 5 patients, the same measurement was performed 1, 3, and 12 months 
      after surgery. RESULTS: PC-MRI showed a strong positive correlation between the 
      flow rate and the third power of vessel diameter in both healthy volunteers 
      (r = 0.82, P < 0.0001) and IA patients (r = 0.90, P < 0.0001), indicating the 
      constant WSS. Of the 18 arteries in 5 patients, WSS increased in 7 arteries and 
      decreased in 11 arteries immediately after surgery. In the WSS-increased group, 
      WSS returned to the preoperative value in the third postoperative month. In the 
      WSS-decreased group, WSS increased in the 12th month, but did not return to the 
      preoperative level. CONCLUSIONS: In a physiological state, WSS was constant in 
      intracranial arteries. Changed WSS after bypass surgery tended to return to the 
      preoperative value, suggesting that vessel diameter and flow rate might be 
      controlled so that WSS remains constant.
FAU - Kataoka, Hiroharu
AU  - Kataoka H
AUID- ORCID: 0000-0001-8507-7557
AD  - Department of Neurosurgery, National Cerebral and Cardiovascular Center, 54 
      Shogoinkawahara-cho, Sakyo-ku, Kyoto, 565-8565, Japan. 
      kataoka@kuhp.kyoto-u.ac.jp.
AD  - Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 
      Japan. kataoka@kuhp.kyoto-u.ac.jp.
FAU - Makino, Yasuhide
AU  - Makino Y
AD  - Department of Neurosurgery, National Cerebral and Cardiovascular Center, 54 
      Shogoinkawahara-cho, Sakyo-ku, Kyoto, 565-8565, Japan.
AD  - Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 
      Japan.
FAU - Takanishi, Kiyofumi
AU  - Takanishi K
AD  - Center for Advanced Biomedical Science (TWIns), Waseda University, Tokyo, Japan.
FAU - Kimura, Yohei
AU  - Kimura Y
AD  - Center for Advanced Biomedical Science (TWIns), Waseda University, Tokyo, Japan.
FAU - Takamura, Kenji
AU  - Takamura K
AD  - Center for Advanced Biomedical Science (TWIns), Waseda University, Tokyo, Japan.
FAU - Yagi, Takanobu
AU  - Yagi T
AD  - Center for Advanced Biomedical Science (TWIns), Waseda University, Tokyo, Japan.
FAU - Iguchi, Satoshi
AU  - Iguchi S
AD  - Department of Investigative Radiology, National Cerebral and Cardiovascular 
      Center Research Institute, Osaka, Japan.
FAU - Yamamoto, Akihide
AU  - Yamamoto A
AD  - Department of Investigative Radiology, National Cerebral and Cardiovascular 
      Center Research Institute, Osaka, Japan.
FAU - Iida, Hidehiro
AU  - Iida H
AD  - Department of Investigative Radiology, National Cerebral and Cardiovascular 
      Center Research Institute, Osaka, Japan.
FAU - Ogata, Soshiro
AU  - Ogata S
AD  - Center for Cerebral and Cardiovascular Disease Information, National Cerebral and 
      Cardiovascular Center, Suita, Osaka, Japan.
FAU - Nishimura, Kunihiro
AU  - Nishimura K
AD  - Center for Cerebral and Cardiovascular Disease Information, National Cerebral and 
      Cardiovascular Center, Suita, Osaka, Japan.
FAU - Nakamura, Masanori
AU  - Nakamura M
AD  - Department of Mechanical Engineering, Nagoya Institute of Technology, Nagoya, 
      Japan.
FAU - Umezu, Mitsuo
AU  - Umezu M
AD  - Center for Advanced Biomedical Science (TWIns), Waseda University, Tokyo, Japan.
FAU - Iihara, Koji
AU  - Iihara K
AD  - Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu 
      University, Fukuoka, Japan.
FAU - Takahashi, Jun C
AU  - Takahashi JC
AD  - Department of Neurosurgery, National Cerebral and Cardiovascular Center, 54 
      Shogoinkawahara-cho, Sakyo-ku, Kyoto, 565-8565, Japan.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20180813
PL  - Austria
TA  - Acta Neurochir (Wien)
JT  - Acta neurochirurgica
JID - 0151000
SB  - IM
MH  - Adult
MH  - Cerebral Arteries/pathology
MH  - Cerebral Revascularization/*adverse effects/methods
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Intracranial Aneurysm/*surgery
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/diagnostic imaging/etiology/*pathology
MH  - Stress, Mechanical
OTO - NOTNLM
OT  - Bypass surgery
OT  - Intracranial aneurysm
OT  - Magnetic resonance imaging
OT  - Phase contrast
OT  - Wall shear stress
EDAT- 2018/08/14 06:00
MHDA- 2019/09/20 06:00
CRDT- 2018/08/14 06:00
PHST- 2018/05/10 00:00 [received]
PHST- 2018/08/05 00:00 [accepted]
PHST- 2018/08/14 06:00 [pubmed]
PHST- 2019/09/20 06:00 [medline]
PHST- 2018/08/14 06:00 [entrez]
AID - 10.1007/s00701-018-3653-2 [pii]
AID - 10.1007/s00701-018-3653-2 [doi]
PST - ppublish
SO  - Acta Neurochir (Wien). 2018 Oct;160(10):1945-1953. doi: 
      10.1007/s00701-018-3653-2. Epub 2018 Aug 13.