PMID- 30107828
OWN - NLM
STAT- MEDLINE
DCOM- 20180831
LR  - 20220318
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 18
IP  - 1
DP  - 2018 Aug 14
TI  - Studying the factors related to refractive error regression after PRK surgery.
PG  - 198
LID - 10.1186/s12886-018-0879-y [doi]
LID - 198
AB  - BACKGTOUND: Photorefractive keratectomy (PRK) is used for a wide range of 
      refractive errors such as low to moderate myopia, hyperopia and astigmatism. 
      While many improvements have been made in laser application and accuracy as well 
      as the modes of corneal flap removal, and although the results are somewhat 
      predictable, regression of refractive errors is still a common complaint among 
      the patients undergoing refractive surgery with Excimer Laser. We aimed to 
      determine related factors of regression following photorefractive keratectomy 
      (PRK) in different types of refractive errors. METHODS: This cross-sectional 
      study included patients who had undergone PRK more than 6 months previously and 
      investigated refractive error regression and related factors. The participants 
      were those who had PRK eye surgery for the first time from 2013 to 2016 using 
      Technolas 217z100. A refraction value of spherical equivalent > 0.75 D after 
      cycloplegic refraction was defined as refractive error regression. RESULTS: A 
      total of 293 eyes on 150 subjects were studied. The preoperative refractive error 
      of the eyes were as follows: 5.5% were myopic, 1% were hyperopic, 4.8% had 
      astigmatism, 76% had myopic astigmatism and 12.6% had hyperopic astigmatism. 
      Regressed and non-regressed eyes were assessed using the generalized estimating 
      equations for the probabilistic variables of demographic characteristics, 
      topography and eye refraction. The variables of simulated keratometry astigmatism 
      (simK) (OR = 2.8; p = 0.04), 5 mm irregularity (OR = 3.56; p = 0.01) and sphere 
      value (OR = 1.98; p = 0.01) were significantly related to refractive error 
      regression. There was no significant relationship between the regressed and 
      non-regressed eyes of the same person (p >/= 0.05). CONCLUSION: There was a 
      positive relationship between the increase of 5 mm irregularity, simK, sphere 
      value before surgery and refractive error regression. Age, sex and type of 
      refraction error of the patient and the expertise of the PRK surgeon could change 
      the general results; therefore, not all cases should be dealt with identically.
FAU - Naderi, Mehdi
AU  - Naderi M
AD  - Department of Clinical Epidemiology, School of Public Health, Safety Promotion 
      and Injury Prevention Research Center, Shahid Beheshti University of Medical 
      Sciences, Chamran Highway, Velenjak, Daneshjoo Blvd, Tehran, I.R, Iran.
FAU - Sabour, Siamak
AU  - Sabour S
AUID- ORCID: 0000-0002-1928-992X
AD  - Department of Clinical Epidemiology, School of Public Health, Safety Promotion 
      and Injury Prevention Research Center, Shahid Beheshti University of Medical 
      Sciences, Chamran Highway, Velenjak, Daneshjoo Blvd, Tehran, I.R, Iran. 
      s.sabour@sbmu.ac.ir.
FAU - Khodakarim, Soheila
AU  - Khodakarim S
AD  - Department of Clinical Epidemiology, School of Public Health, Safety Promotion 
      and Injury Prevention Research Center, Shahid Beheshti University of Medical 
      Sciences, Chamran Highway, Velenjak, Daneshjoo Blvd, Tehran, I.R, Iran.
FAU - Daneshgar, Farid
AU  - Daneshgar F
AD  - Department of Ophthalmology, School of Medicine, Kermanshah University of Medical 
      Sciences, Kermanshah, Iran.
LA  - eng
PT  - Journal Article
DEP - 20180814
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Adult
MH  - Astigmatism/physiopathology/*surgery
MH  - Cornea/surgery
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Lasers, Excimer/*statistics & numerical data/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Myopia/physiopathology/*surgery
MH  - *Photorefractive Keratectomy
MH  - Refraction, Ocular/*physiology
MH  - Treatment Outcome
MH  - *Visual Acuity
MH  - Young Adult
PMC - PMC6092795
OTO - NOTNLM
OT  - PRK surgery
OT  - Refractive error regression
OT  - Related factors
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The study was conducted after 
      obtaining the oral and written informed consent from the patients and the ethical 
      clearance from Shahid Beheshti University of Medical Sciences and Kermanshah 
      University of Medical Sciences in accordance with the tenets of the Declaration 
      of Helsinki. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The 
      authors declare that they have no competing interests. PUBLISHER'S NOTE: Springer 
      Nature remains neutral with regard to jurisdictional claims in published maps and 
      institutional affiliations.
EDAT- 2018/08/16 06:00
MHDA- 2018/09/01 06:00
PMCR- 2018/08/14
CRDT- 2018/08/16 06:00
PHST- 2018/01/15 00:00 [received]
PHST- 2018/08/07 00:00 [accepted]
PHST- 2018/08/16 06:00 [entrez]
PHST- 2018/08/16 06:00 [pubmed]
PHST- 2018/09/01 06:00 [medline]
PHST- 2018/08/14 00:00 [pmc-release]
AID - 10.1186/s12886-018-0879-y [pii]
AID - 879 [pii]
AID - 10.1186/s12886-018-0879-y [doi]
PST - epublish
SO  - BMC Ophthalmol. 2018 Aug 14;18(1):198. doi: 10.1186/s12886-018-0879-y.