PMID- 30110273
OWN - NLM
STAT- MEDLINE
DCOM- 20181218
LR  - 20210214
IS  - 2191-0308 (Electronic)
IS  - 0048-7554 (Linking)
VI  - 33
IP  - 4
DP  - 2018 Dec 19
TI  - Exposure to persistent organic pollutants: impact on women's health.
PG  - 331-348
LID - 10.1515/reveh-2018-0018 [doi]
AB  - This literature review focuses on the causal relationship between persistent 
      organic pollutants (POPs) exposure and women's health disorders, particularly 
      cancer, cardio-metabolic events and reproductive health. Progressive 
      industrialization has resulted in the production of a multitude of chemicals that 
      are released into the environment on a daily basis. Environmental chemicals or 
      pollutants are not only hazardous to our ecosystem but also lead to various 
      health problems that affect the human population worldwide irrespective of 
      gender, race or age. However, most environmental health studies that have been 
      conducted, until recently, were exclusively biased with regard to sex and gender, 
      beginning with exposure studies that were reported mostly in male, occupational 
      workers and animal studies being carried out mostly in male rodent models. 
      Health-related issues pertaining to women of all age groups have not been studied 
      thoroughly and rather disregarded in most aspects of basic health science 
      research and it is therefore pertinent that we address these limitations in 
      environmental health. The review also addresses studies looking at the 
      associations between health outcomes and exposures to POPs, particularly, 
      polychlorinated biphenyls (PCBs), dioxins and pesticides, reported in cohort 
      studies while accounting for gender differences. Considering that current levels 
      of POPs in women can also impact future generations, informative guidelines 
      related to dietary patterns and exposure history are needed for women of 
      reproductive age. Additionally, occupational cohorts of highly exposed women 
      worldwide, such as women working in manufacturing plants and female pesticide 
      applicators are required to gather more information on population susceptibility 
      and disease pathology.
FAU - Wahlang, Banrida
AU  - Wahlang B
AUID- ORCID: 0000-0002-4356-1743
AD  - Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, 
      University of Louisville School of Medicine, 505 S. Hancock Street, CTRB, 
      Louisville, KY 40202-1617, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Rev Environ Health
JT  - Reviews on environmental health
JID - 0425754
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Environmental Pollutants/*adverse effects
MH  - Female
MH  - Heart Diseases/etiology/*physiopathology
MH  - Humans
MH  - Metabolic Diseases/etiology/*physiopathology
MH  - Neoplasms/etiology/*physiopathology
MH  - *Reproductive Health
MH  - *Women's Health
OTO - NOTNLM
OT  - POPs
OT  - breast cancer
OT  - cardiovascular
OT  - metabolic
OT  - women
EDAT- 2018/08/16 06:00
MHDA- 2018/12/19 06:00
CRDT- 2018/08/16 06:00
PHST- 2018/03/24 00:00 [received]
PHST- 2018/07/18 00:00 [accepted]
PHST- 2018/08/16 06:00 [pubmed]
PHST- 2018/12/19 06:00 [medline]
PHST- 2018/08/16 06:00 [entrez]
AID - reveh-2018-0018 [pii]
AID - 10.1515/reveh-2018-0018 [doi]
PST - ppublish
SO  - Rev Environ Health. 2018 Dec 19;33(4):331-348. doi: 10.1515/reveh-2018-0018.