PMID- 30121857 OWN - NLM STAT- MEDLINE DCOM- 20191008 LR - 20191008 IS - 1708-0428 (Electronic) IS - 0960-8923 (Linking) VI - 28 IP - 11 DP - 2018 Nov TI - Adverse Events of the Duodenal-Jejunal Bypass Liner: a Systematic Review. PG - 3669-3677 LID - 10.1007/s11695-018-3441-3 [doi] AB - A systematic review was conducted on adverse events (AEs) associated with the use of the duodenal-jejunal bypass liner (DJBL). PubMed, EMBASE, and Cochrane library were searched up to January 2018. The quality of reporting AEs was determined by the McHarm questionnaire and the risk of bias by the Newcastle-Ottawa scale. Thirty-eight studies were included. The comparability of the studies was low and the McHarm questionnaire showed incompleteness for most parameters in all studies. A total of 891 AEs were reported in 1056 patients. Thirty-three AEs (3.7%) were classified as severe, including hepatic abscess and esophageal perforation. The anchor of the DJBL caused or likely caused 85% of the SAEs. To improve the safety margin of the DJBL, adjustments to the anchoring system are needed. FAU - Betzel, Bark AU - Betzel B AUID- ORCID: 0000-0003-0593-8375 AD - Department of Gastroenterology and Hepatology, Radboud University Medical Center, P.O. Box 9101, code 455, Nijmegen, The Netherlands. Bark.Betzel@radboudumc.nl. FAU - Drenth, Joost P H AU - Drenth JPH AD - Department of Gastroenterology and Hepatology, Radboud University Medical Center, P.O. Box 9101, code 455, Nijmegen, The Netherlands. FAU - Siersema, Peter D AU - Siersema PD AD - Department of Gastroenterology and Hepatology, Radboud University Medical Center, P.O. Box 9101, code 455, Nijmegen, The Netherlands. LA - eng PT - Journal Article PT - Systematic Review PL - United States TA - Obes Surg JT - Obesity surgery JID - 9106714 SB - IM MH - Bariatric Surgery/*adverse effects/*instrumentation/methods MH - Duodenum/*surgery MH - Humans MH - Jejunum/*surgery MH - Obesity, Morbid/*surgery MH - Treatment Outcome OTO - NOTNLM OT - Acute pancreatitis OT - Adverse events OT - Duodenal-jejunal bypass liner OT - Endobarrier OT - Gastrointestinal hemorrhage OT - Hepatic abscess OT - Migration OT - Obstruction OT - Perforation EDAT- 2018/08/20 06:00 MHDA- 2019/10/09 06:00 CRDT- 2018/08/20 06:00 PHST- 2018/08/20 06:00 [pubmed] PHST- 2019/10/09 06:00 [medline] PHST- 2018/08/20 06:00 [entrez] AID - 10.1007/s11695-018-3441-3 [pii] AID - 10.1007/s11695-018-3441-3 [doi] PST - ppublish SO - Obes Surg. 2018 Nov;28(11):3669-3677. doi: 10.1007/s11695-018-3441-3.