PMID- 30131683
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1662-5161 (Print)
IS  - 1662-5161 (Electronic)
IS  - 1662-5161 (Linking)
VI  - 12
DP  - 2018
TI  - Training-Induced Changes in Rapid Auditory Processing in Children With Specific 
      Language Impairment: Electrophysiological Indicators.
PG  - 310
LID - 10.3389/fnhum.2018.00310 [doi]
LID - 310
AB  - The brain's ability to recognize acoustic changes occurring in rapid temporal 
      succession is important for speech and successful language development. Children 
      with specific language impairment (SLI) are characterized by deficient dynamics 
      of temporal information processing (TIP) in the millisecond time range 
      accompanied by disordered language development. Furthermore, previous studies 
      have found that intervention based on amelioration of TIP resulted in improvement 
      of both language and other cognitive functions. This study aimed to explain the 
      changes associated with TIP training from the perspective of event-related 
      potentials (ERPs). Thirty-six children aged 5-8 years (26 boys, 10 girls) 
      diagnosed with SLI underwent two types of intense audio-visual computer 
      intervention: experimental TIP training targeted at the millisecond time range (n 
      = 18) or control non-TIP training (n = 18). Paired 50 ms tones of 1000 Hz and 
      1200 Hz were presented with inter-stimulus intervals (ISIs) of either 50 ms 
      (Short ISI Condition) or 200 ms (Long ISI Condition). Auditory ERPs were measured 
      in a passive oddball paradigm before and after each type of training. The 
      mismatch negativity (MMN) paradigm was applied as an electrophysiological 
      indicator of the brain's ability to automatically detect violations of regularity 
      in paired tones presented in rapid succession. Moreover, the P3a component was 
      also analyzed. After 24 sessions of temporal training (in the experimental group) 
      MMN amplitude enhancement was observed in both ISI conditions, reflecting 
      increased efficiency in perceiving changes in rapid auditory sequences. In both 
      experimental and control groups, P3a amplitude was enhanced in both ISIs. This 
      may be due to the improvement of involuntary attention shifting to the auditory 
      events involved in each training type. To conclude, temporal training, compared 
      to non-temporal control training, improved the ability to detect changes in a 
      rapid auditory stream in children with SLI.
FAU - Dacewicz, Anna
AU  - Dacewicz A
AD  - Laboratory of Neuropsychology, Nencki Institute of Experimental Biology of Polish 
      Academy of Sciences, Warsaw, Poland.
FAU - Szymaszek, Aneta
AU  - Szymaszek A
AD  - Laboratory of Neuropsychology, Nencki Institute of Experimental Biology of Polish 
      Academy of Sciences, Warsaw, Poland.
FAU - Nowak, Kamila
AU  - Nowak K
AD  - Laboratory of Social Psychology, Department of Ergonomics, Central Institute for 
      Labour Protection-National Research Institute, Warsaw, Poland.
FAU - Szelag, Elzbieta
AU  - Szelag E
AD  - Laboratory of Neuropsychology, Nencki Institute of Experimental Biology of Polish 
      Academy of Sciences, Warsaw, Poland.
LA  - eng
PT  - Journal Article
DEP - 20180807
PL  - Switzerland
TA  - Front Hum Neurosci
JT  - Frontiers in human neuroscience
JID - 101477954
PMC - PMC6091056
OTO - NOTNLM
OT  - cognitive training
OT  - event related potentials (ERPs)
OT  - specific language impairment (SLI)
OT  - temporal information processing
OT  - temporal windows
EDAT- 2018/08/23 06:00
MHDA- 2018/08/23 06:01
PMCR- 2018/01/01
CRDT- 2018/08/23 06:00
PHST- 2017/10/20 00:00 [received]
PHST- 2018/07/16 00:00 [accepted]
PHST- 2018/08/23 06:00 [entrez]
PHST- 2018/08/23 06:00 [pubmed]
PHST- 2018/08/23 06:01 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - 10.3389/fnhum.2018.00310 [doi]
PST - epublish
SO  - Front Hum Neurosci. 2018 Aug 7;12:310. doi: 10.3389/fnhum.2018.00310. eCollection 
      2018.