PMID- 30136075 OWN - NLM STAT- MEDLINE DCOM- 20181211 LR - 20191201 IS - 1995-8218 (Electronic) IS - 1673-7067 (Print) IS - 1995-8218 (Linking) VI - 34 IP - 6 DP - 2018 Dec TI - Wandering Minds with Wandering Brain Networks. PG - 1017-1028 LID - 10.1007/s12264-018-0278-7 [doi] AB - The default mode network (DMN) is associated with the occurrence of mind-wandering or task-unrelated thought. In contrast, the frontal-parietal network (FPN) and visual network (VS) are involved in tasks with external stimuli. However, it is not clear how these functional network interactions support these two different processes - mind-wandering and on-task - especially with regard to individual variation in the mind-wandering experience. In this study, we investigated the functional connectivity and modular structure among the DMN, FPN, and VS. Our results showed that, compared to the on-task period, mind-wandering was associated with increased DMN activity and increased DMN-VS connectivity. Moreover, mind-wandering was accompanied by a large number of transitional nodes, which expressed a diversity of brain regions. Intriguingly, the functional connectivity of the FPN and VS was strongly correlated with individual behavioral performance. Our findings highlight the individual variation of mind-wandering, which implies the importance of other complementary large-scale brain networks. FAU - Zhou, Xinqi AU - Zhou X AD - Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, 400715, China. AD - Key Laboratory of Cognition and Personality of Ministry of Education, Chongqing, 400715, China. FAU - Lei, Xu AU - Lei X AD - Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, 400715, China. xlei@swu.edu.cn. AD - Key Laboratory of Cognition and Personality of Ministry of Education, Chongqing, 400715, China. xlei@swu.edu.cn. LA - eng PT - Journal Article DEP - 20180822 PL - Singapore TA - Neurosci Bull JT - Neuroscience bulletin JID - 101256850 RN - S88TT14065 (Oxygen) SB - IM MH - Adult MH - Attention/*physiology MH - Brain/diagnostic imaging/*physiology MH - *Brain Mapping MH - Female MH - Humans MH - Image Processing, Computer-Assisted MH - *Intention MH - Magnetic Resonance Imaging MH - Male MH - *Models, Neurological MH - Oxygen/blood MH - Young Adult PMC - PMC6246840 OTO - NOTNLM OT - Default mode network OT - Functional connectivity OT - Mind wandering OT - Modularity COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2018/08/24 06:00 MHDA- 2018/12/12 06:00 PMCR- 2019/12/01 CRDT- 2018/08/24 06:00 PHST- 2018/02/27 00:00 [received] PHST- 2018/06/04 00:00 [accepted] PHST- 2018/08/24 06:00 [pubmed] PHST- 2018/12/12 06:00 [medline] PHST- 2018/08/24 06:00 [entrez] PHST- 2019/12/01 00:00 [pmc-release] AID - 10.1007/s12264-018-0278-7 [pii] AID - 278 [pii] AID - 10.1007/s12264-018-0278-7 [doi] PST - ppublish SO - Neurosci Bull. 2018 Dec;34(6):1017-1028. doi: 10.1007/s12264-018-0278-7. Epub 2018 Aug 22.