PMID- 30136471
OWN - NLM
STAT- MEDLINE
DCOM- 20181017
LR  - 20181017
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 36
IP  - 6
DP  - 2018 Jun 8
TI  - [System of simultaneous extraction and cleaning of 99 veterinary drugs in food].
PG  - 506-517
LID - 10.3724/SP.J.1123.2018.02023 [doi]
AB  - We established a system for the simultaneous extraction and cleaning of 99 
      veterinary drugs from food by ultra-performance liquid chromatography coupled 
      with quadrupole electrostatic field-orbital trap-high-resolution mass 
      spectrometry (UHPLC-Q-Orbitrap HRMS). The system is based on the supported 
      liquid-liquid extraction technology through one-off pretreatment, which covers 
      the common eight categories of physical and chemical properties, and the 
      extraction and purification of 99 different veterinary drug residues. At the same 
      time, the one-step multi residue screening of 99 veterinary drug residues has 
      been realized using HRMS. The results showed that the method was suitable for 
      extraction from milk, pork, and fish. The 99 veterinary drugs showed a good 
      linear relationship in the concentration range of 0.001-0.1 mug/mL, the limit of 
      quantification was 0.5-20.0 mug/kg, the average recoveries were 60%-120%, and the 
      relative standard deviations (RSDs) were not more than 15%. The pre-processing 
      and instrumental analysis of this method have high detection efficiency, strong 
      maneuver ability, and strong compatibility with different physical and chemical 
      compounds. Moreover, the detection limit can meet all the objects of the test and 
      greatly reduce the detection cost.
FAU - Li, Shuang
AU  - Li S
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
AD  - Key Laboratory of Applied Marine Biotechnology of Chinese Ministry of Education, 
      Ningbo University, Ningbo 315211, China.
FAU - Chen, Shubing
AU  - Chen S
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
FAU - Li, Luqing
AU  - Li L
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
FAU - Xu, Xuwen
AU  - Xu X
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
FAU - Chen, Xianfeng
AU  - Chen X
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
FAU - Zhong, Yingying
AU  - Zhong Y
AD  - Ningbo Entry-Exit Inspection and Quarantine Bureau Technology Center, Ningbo 
      315211, China.
FAU - Zhang, Yaheng
AU  - Zhang Y
AD  - Comprehensive Technical Center of Gansu Entry and Exit Inspection and Quarantine 
      Bureau, Lanzhou 730010, China.
FAU - Wang, Chuanxian
AU  - Wang C
AD  - Shanghai Entry-Exit Inspection and Quarantine Bureau, Shanghai 200135, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Veterinary Drugs)
SB  - IM
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - Drug Residues/*analysis
MH  - Fishes
MH  - Limit of Detection
MH  - Liquid-Liquid Extraction
MH  - Mass Spectrometry
MH  - Milk/*chemistry
MH  - Red Meat/*analysis
MH  - Seafood/*analysis
MH  - Tandem Mass Spectrometry
MH  - Veterinary Drugs/*analysis
OTO - NOTNLM
OT  - carrier supported liquid-liquid extraction
OT  - food
OT  - ultra performance liquid chromatography coupled with quadrupole electrostatic 
      field-orbital trap-high-resolution mass spectrometry (UHPLC-Q-Orbitrap HRMS)
OT  - veterinary drugs
EDAT- 2018/08/24 06:00
MHDA- 2018/10/18 06:00
CRDT- 2018/08/24 06:00
PHST- 2018/08/24 06:00 [entrez]
PHST- 2018/08/24 06:00 [pubmed]
PHST- 2018/10/18 06:00 [medline]
AID - 10.3724/SP.J.1123.2018.02023 [doi]
PST - ppublish
SO  - Se Pu. 2018 Jun 8;36(6):506-517. doi: 10.3724/SP.J.1123.2018.02023.