PMID- 30136517
OWN - NLM
STAT- MEDLINE
DCOM- 20181017
LR  - 20181017
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 36
IP  - 4
DP  - 2018 Apr 8
TI  - [Determination of 14 sweeteners in liquid foods by hydrophilic interaction liquid 
      chromatography-tandem mass spectrometry].
PG  - 351-355
LID - 10.3724/SP.J.1123.2017.10023 [doi]
AB  - A method for the simultaneous determination of six artificial sweeteners and 
      eight steviol glycosides in liquid food samples by hydrophilic interaction liquid 
      chromatography-tandem mass spectrometry (HILIC-MS/MS) was developed.The 
      sweeteners in the samples were separated by a Waters Xbridge Amide column (150 
      mmx5.0 mm, 3.5 mum) at 35℃, and eluted with acetonitrile-10 mmol/L ammonium 
      formate (65:35, v/v) at a flow rate of 0.4 mL/min.Then, the analytes were 
      detected using an electrospray ion source in negative mode (ESI(-)) under 
      multiple reaction monitoring (MRM) mode.Good linear relationships were obtained, 
      and the correlation coefficients (r(2)) of the 14 sweeteners were greater than 
      0.995.The limits of detection (LODs, S/N=3) and the limits of quantification 
      (LOQs, S/N=10) ranged from 0.03 to 0.7 mg/kg and 0.1 to 2.2 mg/kg, 
      respectively.The average recoveries varied from 80.8% to 108.7% at spiked levels 
      of 2, 5 and 20 mg/kg, and the relative standard deviations (RSDs) ranged from 
      1.5% to 7.7%(n=6).The proposed method is simple, accurate and sensitive for the 
      simultaneous determination of the 14 sweeteners in liquid food samples.
FAU - Fan, Guangyu
AU  - Fan G
AD  - Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 
      100176, China. ##Email#.
AD  - Lianyungang Entry-Exit Inspection and Quarantine Bureau, Lianyungang 222042, 
      China. ##Email#.
FAU - Feng, Feng
AU  - Feng F
AD  - Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 
      100176, China. ##Email#.
FAU - Zhang, Feng
AU  - Zhang F
AD  - Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 
      100176, China. ##Email#.
FAU - Gao, Fei
AU  - Gao F
AD  - Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 
      100176, China. ##Email#.
FAU - Li, Xiaoming
AU  - Li X
AD  - Jinan Entry-Exit Inspection and Quarantine Bureau, Jinan 250014, China. ##Email#.
FAU - Liang, Zhengang
AU  - Liang Z
AD  - Technology Center of Hainan Entry-Exit Inspection and Quarantine Bureau, Haikou 
      570311, China. ##Email#.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Diterpenes, Kaurane)
RN  - 0 (Glucosides)
RN  - 0 (Sweetening Agents)
RN  - 0YON5MXJ9P (stevioside)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Diterpenes, Kaurane/*analysis
MH  - *Food Analysis
MH  - Glucosides/*analysis
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Limit of Detection
MH  - Sweetening Agents/*analysis
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - artificial sweeteners
OT  - hydrophilic interaction liquid chromatography (HILIC)
OT  - liquid food
OT  - steviol glycosides
OT  - triple quadrupole mass spectrometry
EDAT- 2018/08/24 06:00
MHDA- 2018/10/18 06:00
CRDT- 2018/08/24 06:00
PHST- 2018/08/24 06:00 [entrez]
PHST- 2018/08/24 06:00 [pubmed]
PHST- 2018/10/18 06:00 [medline]
AID - 10.3724/SP.J.1123.2017.10023 [doi]
PST - ppublish
SO  - Se Pu. 2018 Apr 8;36(4):351-355. doi: 10.3724/SP.J.1123.2017.10023.