PMID- 30138230
OWN - NLM
STAT- MEDLINE
DCOM- 20190911
LR  - 20190911
IS  - 1557-0584 (Electronic)
IS  - 1557-0576 (Linking)
VI  - 42
IP  - 4
DP  - 2018 Oct
TI  - Minimal Clinically Important Difference of the 6-Minute Walk Test in People With 
      Stroke.
PG  - 235-240
LID - 10.1097/NPT.0000000000000236 [doi]
AB  - BACKGROUND AND PURPOSE: The 6-minute walk test (6MWT) is commonly used in people 
      with stroke. The purpose of this study was to estimate the minimal clinically 
      important difference (MCID) of the 6MWT 2 months poststroke. METHODS: We 
      performed a secondary analysis of data from a rehabilitation trial. Participants 
      underwent physical therapy between 2 and 6 months poststroke and the 6MWT was 
      measured before and after. Two anchors of important change were used: the 
      modified Rankin Scale (mRS) and the Stroke Impact Scale (SIS). The MCID for the 
      6MWT was estimated using receiver operating characteristic curves for the entire 
      sample and for 2 subgroups: initial gait speed (IGS) <0.40 m/s and >/=0.40 m/s. 
      RESULTS: For the entire sample, the estimated MCID of the 6MWT was 71 m with the 
      mRS as the anchor (area under the curve [AUC] = 0.66) and 65 m with the SIS as 
      the anchor (AUC = 0.59). For participants with IGS <0.40 m/s, the estimated MCID 
      was 44 m with the mRS as the anchor (AUC = 0.72) and 34 m with the SIS as the 
      anchor (AUC = 0.62). For participants with IGS >/=0.40 m/s, the estimated MCID was 
      71 m with the mRS as the anchor (AUC = 0.59) and 130 m with the SIS as the anchor 
      (AUC = 0.56). DISCUSSION AND CONCLUSIONS: Between 2 and 6 months poststroke, 
      people whose IGS is <0.40 m/s and experience a 44-m improvement in the 6MWT may 
      exhibit meaningful improvement in disability. However, we were not able to 
      estimate an accurate MCID for the 6MWT in people whose IGS was >/=0.40 m/s. MCID 
      values should be estimated across different levels of function and anchors of 
      importance.Video Abstract available for more insights from the authors (see 
      Video, Supplemental Digital Content 1, available at: 
      http://links.lww.com/JNPT/A232).
FAU - Fulk, George D
AU  - Fulk GD
AD  - Department of Physical Therapy Education (G.D.F.), SUNY Upstate Medical 
      University, Syracuse, New York. Department of Mathematics (Y.H.), Clarkson 
      University, Potsdam, New York.
FAU - He, Ying
AU  - He Y
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - J Neurol Phys Ther
JT  - Journal of neurologic physical therapy : JNPT
JID - 101193365
SB  - IM
MH  - Aged
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Stroke/*physiopathology/*therapy
MH  - Stroke Rehabilitation
MH  - *Walk Test
EDAT- 2018/08/24 06:00
MHDA- 2019/09/12 06:00
CRDT- 2018/08/24 06:00
PHST- 2018/08/24 06:00 [pubmed]
PHST- 2019/09/12 06:00 [medline]
PHST- 2018/08/24 06:00 [entrez]
AID - 10.1097/NPT.0000000000000236 [doi]
PST - ppublish
SO  - J Neurol Phys Ther. 2018 Oct;42(4):235-240. doi: 10.1097/NPT.0000000000000236.