PMID- 30150040
OWN - NLM
STAT- MEDLINE
DCOM- 20181126
LR  - 20181126
IS  - 1872-7727 (Electronic)
IS  - 0720-048X (Linking)
VI  - 106
DP  - 2018 Sep
TI  - The "extracapsular cystic" sign in pancreatic serous cystic neoplasms: A 
      clinicopathologic study of 177 patients with cystic pancreatic lesions.
PG  - 167-172
LID - S0720-048X(18)30270-5 [pii]
LID - 10.1016/j.ejrad.2018.08.002 [doi]
AB  - OBJECTIVE: To assess a new imaging feature that we have named the extracapsular 
      cystic sign which can make a constructive contribution towards differentiating 
      serous cystic neoplasms (SCNs) from other pancreatic cystic lesions. MATERIAL AND 
      METHODS: We retrospectively reviewed 177 CTs/MRIs of patients who underwent 
      pancreatic resection of cystic lesions at two institutions from January 
      2011/2013, to September 2017. For each patient, demographic information, clinical 
      presentation, especially imaging features were carefully investigated by two 
      experienced abdominal radiologists, retrospectively. All statistical analyses 
      were performed using SPSS V.23.0. RESULTS: Twenty-one lesions had extracapsular 
      cystic signs which were newly discovered, 17 (28.3%) of 60 SCNs and 4 (3.4%) 
      (mucinous cystic neoplasm = 1, walled-off necrosis = 2, retention cyst = 1) of 
      117 Non-SCNs were included, from which indicating that the extracapsular cystic 
      sign was more often detected on SCNs. As for 21 lesions, 86% (n = 18) were 
      females, and mean age at diagnosis was 51.2 years. 71% (n = 15) located in the 
      pancreatic body and tail. Average size was 27.2 mm (23.7-53.4), mean (SD) ratio 
      of biggest daughter cyst to mother cyst was 0.51[0.14] (p = 0.99), average (SD) 
      angle between two of them was 105.5 degrees  [14.9] (p = 0.84). The average time interval 
      between last imaging examination and surgery was 8.4 days. CONCLUSIONS: The new 
      sign named the extracapsular cystic sign in SCNs may help differentiate SCNs from 
      other pancreatic cystic lesions. Furthermore, this study supports an original 
      diagnosis for SCNs when the sign of extracapsular cyst appears.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Chen, Hai-Yan
AU  - Chen HY
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China.
FAU - Zhao, Jin
AU  - Zhao J
AD  - Department of Radiology, Zhejiang Hospital, Hangzhou, China.
FAU - Lu, Yuan-Fei
AU  - Lu YF
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China.
FAU - Lv, Sang-Ying
AU  - Lv SY
AD  - Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of 
      Medicine, Hangzhou, China.
FAU - Chen, Jie-Yu
AU  - Chen JY
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China.
FAU - Pan, Yao
AU  - Pan Y
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China.
FAU - Shi, Dan
AU  - Shi D
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China.
FAU - Xu, Xiu-Fang
AU  - Xu XF
AD  - Department of Radiology, Hangzhou Medical College, Hangzhou, China. Electronic 
      address: hzyxyxuxiufang@126.com.
FAU - Yu, Ri-Sheng
AU  - Yu RS
AD  - Department of Radiology, Second Affiliated Hospital, Zhejiang University School 
      of Medicine, Hangzhou, China. Electronic address: risheng-yu@zju.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20180804
PL  - Ireland
TA  - Eur J Radiol
JT  - European journal of radiology
JID - 8106411
SB  - IM
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Pancreas/diagnostic imaging/pathology
MH  - Pancreatic Cyst/diagnostic imaging/pathology
MH  - Pancreatic Neoplasms/*diagnostic imaging/pathology
MH  - Retrospective Studies
MH  - Tomography, X-Ray Computed/*methods
OTO - NOTNLM
OT  - Diagnostic imaging
OT  - Differential diagnosis
OT  - Pancreatic neoplasms
OT  - Retrospective study
OT  - Serous cystadenomas
EDAT- 2018/08/29 06:00
MHDA- 2018/11/27 06:00
CRDT- 2018/08/29 06:00
PHST- 2018/03/23 00:00 [received]
PHST- 2018/07/30 00:00 [revised]
PHST- 2018/08/02 00:00 [accepted]
PHST- 2018/08/29 06:00 [entrez]
PHST- 2018/08/29 06:00 [pubmed]
PHST- 2018/11/27 06:00 [medline]
AID - S0720-048X(18)30270-5 [pii]
AID - 10.1016/j.ejrad.2018.08.002 [doi]
PST - ppublish
SO  - Eur J Radiol. 2018 Sep;106:167-172. doi: 10.1016/j.ejrad.2018.08.002. Epub 2018 
      Aug 4.