PMID- 30157585
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201204
IS  - 2005-6419 (Print)
IS  - 2005-7563 (Electronic)
IS  - 2005-6419 (Linking)
VI  - 71
IP  - 5
DP  - 2018 Oct
TI  - What is the proper way to apply the multiple comparison test?
PG  - 353-360
LID - 10.4097/kja.d.18.00242 [doi]
AB  - Multiple comparisons tests (MCTs) are performed several times on the mean of 
      experimental conditions. When the null hypothesis is rejected in a validation, 
      MCTs are performed when certain experimental conditions have a statistically 
      significant mean difference or there is a specific aspect between the group 
      means. A problem occurs if the error rate increases while multiple hypothesis 
      tests are performed simultaneously. Consequently, in an MCT, it is necessary to 
      control the error rate to an appropriate level. In this paper, we discuss how to 
      test multiple hypotheses simultaneously while limiting type I error rate, which 
      is caused by alpha inflation. To choose the appropriate test, we must maintain the 
      balance between statistical power and type I error rate. If the test is too 
      conservative, a type I error is not likely to occur. However, concurrently, the 
      test may have insufficient power resulted in increased probability of type II 
      error occurrence. Most researchers may hope to find the best way of adjusting the 
      type I error rate to discriminate the real differences between observed data 
      without wasting too much statistical power. It is expected that this paper will 
      help researchers understand the differences between MCTs and apply them 
      appropriately.
FAU - Lee, Sangseok
AU  - Lee S
AD  - Department of Anesthesiology and Pain Medicine, Sanggye Paik Hospital, Inje 
      University College of Medicine, Seoul, Korea.
FAU - Lee, Dong Kyu
AU  - Lee DK
AD  - Department of Anesthesiology and Pain Medicine, Guro Hospital, Korea University 
      School of Medicine, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20180828
PL  - Korea (South)
TA  - Korean J Anesthesiol
JT  - Korean journal of anesthesiology
JID - 101502451
EIN - Korean J Anesthesiol. 2020 Dec;73(6):572. PMID: 33271011
PMC - PMC6193594
OTO - NOTNLM
OT  - Alpha inflation
OT  - Analysis of variance
OT  - Bonferroni
OT  - Dunnett
OT  - Multiple comparison
OT  - Scheffe
OT  - Statistics
EDAT- 2018/08/31 06:00
MHDA- 2018/08/31 06:01
PMCR- 2018/10/01
CRDT- 2018/08/30 06:00
PHST- 2018/08/19 00:00 [received]
PHST- 2018/08/27 00:00 [accepted]
PHST- 2018/08/31 06:00 [pubmed]
PHST- 2018/08/31 06:01 [medline]
PHST- 2018/08/30 06:00 [entrez]
PHST- 2018/10/01 00:00 [pmc-release]
AID - kja.d.18.00242 [pii]
AID - kja-d-18-00242 [pii]
AID - 10.4097/kja.d.18.00242 [doi]
PST - ppublish
SO  - Korean J Anesthesiol. 2018 Oct;71(5):353-360. doi: 10.4097/kja.d.18.00242. Epub 
      2018 Aug 28.