PMID- 30158323 OWN - NLM STAT- MEDLINE DCOM- 20181211 LR - 20220408 IS - 1557-2501 (Electronic) IS - 1042-3931 (Linking) VI - 30 IP - 9 DP - 2018 Sep TI - Transradial Intervention in Patients With Non-ST Elevation Acute Coronary Syndrome Using One 4.0 Fr Sheath and One Sheathless Guide Catheter Via a Single Puncture Site: The 1-1-1 Strategy. PG - 316-323 AB - OBJECTIVES: The optimal primary transradial intervention (TRI) technique has not been established in non-ST segment elevation acute coronary syndrome (NSTEACS) patients, because they often, but not always, undergo immediate revascularization after coronary angiography (CAG). Moreover, TRI failure has been reported in 5%-10% of cases. We investigated whether a newly designed strategy of immediate TRI using one sheathless hydrophilic-coated guiding catheter (SH-GC) after diagnostic CAG with one 4.0 Fr sheath via a single access site (the 1-1-1 strategy) could be beneficial for NSTEACS patients. METHODS: We performed immediate TRI prospectively using SH-GC in consecutive NSTEACS patients in our hospital and compared the procedural success rate with that of conventional TRI performed before this study. RESULTS: Between 2015 and 2017, immediate TRI using SH-GC was performed in 330 consecutive NSTEACS patients after CAG using a 4.0 Fr sheath. Compared with the conventional TRI group (n = 330), the procedural success rate was significantly higher in the SH-GC group (P<.01), as SH-GC prevented TRI failure due to radial spasm (P<.01). SH-GC use was also significantly associated with completion of both diagnostic CAG and immediate TRI using only one sheath (P<.001) and one guiding catheter (P=.02). Multivariate analysis revealed that SH-GC use was an independent predictor of successful TRI (P<.01). The rates of major adverse cardiac events were comparable; however, rates of major access-site bleeding (P<.01) and blood transfusion (P=.02) were significantly lower in the SH-GC group. CONCLUSIONS: The 1-1-1 strategy using SH-GC may offer better TRI treatment than conventional systems for NSTEACS patients and simultaneously prevent access-site bleeding. FAU - Horie, Kazunori AU - Horie K AD - Division of Cardiovascular Medicine, Sendai Kousei Hospital, 4-15 Hirose-cho, Aoba-ku, Sendai, Miyagi 980-0873, Japan. horihori1015@gmail.com. FAU - Tada, Norio AU - Tada N FAU - Isawa, Tsuyoshi AU - Isawa T FAU - Matsumoto, Takashi AU - Matsumoto T FAU - Taguri, Masataka AU - Taguri M FAU - Kato, Shigeaki AU - Kato S FAU - Honda, Taku AU - Honda T FAU - Ootomo, Tatsushi AU - Ootomo T FAU - Inoue, Naoto AU - Inoue N LA - eng PT - Journal Article PL - United States TA - J Invasive Cardiol JT - The Journal of invasive cardiology JID - 8917477 SB - IM MH - Acute Coronary Syndrome/diagnosis/*surgery MH - Aged MH - *Cardiac Catheters MH - Coronary Angiography MH - Equipment Design MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Percutaneous Coronary Intervention/*methods MH - Prospective Studies MH - Punctures/*methods MH - Radial Artery MH - Treatment Outcome OTO - NOTNLM OT - access-site management OT - acute MI OT - radial artery access EDAT- 2018/08/31 06:00 MHDA- 2018/12/12 06:00 CRDT- 2018/08/31 06:00 PHST- 2018/08/31 06:00 [entrez] PHST- 2018/08/31 06:00 [pubmed] PHST- 2018/12/12 06:00 [medline] PST - ppublish SO - J Invasive Cardiol. 2018 Sep;30(9):316-323.