PMID- 30159222 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220321 IS - 2210-9099 (Print) IS - 2233-6052 (Electronic) IS - 2210-9099 (Linking) VI - 9 IP - 4 DP - 2018 Aug TI - Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications. PG - 167-174 LID - 10.24171/j.phrp.2018.9.4.05 [doi] AB - OBJECTIVES: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes. METHODS: This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients' HbA1c levels were categorized into good control 7% (>53mmol/mol), and patients' characteristics were analyzed. RESULTS: A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6%)], had a family history of diabetes [n = 256 (39%)] and obesity [n = 95 (14.5%)], all had poor glycemic control. CONCLUSION: This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications. FAU - Haghighatpanah, Mohammad AU - Haghighatpanah M AD - Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India. FAU - Nejad, Amir Sasan Mozaffari AU - Nejad ASM AD - Nutrition Health Research Center, Student Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Haghighatpanah, Maryam AU - Haghighatpanah M AD - Department of Microbiology, Islamic Azad University, Lahijan Branch, Rasht, Iran. FAU - Thunga, Girish AU - Thunga G AD - Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India. FAU - Mallayasamy, Surulivelrajan AU - Mallayasamy S AD - Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India. LA - eng PT - Journal Article PL - Korea (South) TA - Osong Public Health Res Perspect JT - Osong public health and research perspectives JID - 101563309 PMC - PMC6110332 OTO - NOTNLM OT - diabetes complications OT - diabetes mellitus OT - glycemic OT - glycosylated hemoglobin A1c COIS- Conflicts of Interest The authors declare that there was no conflict of interest associated with this paper. EDAT- 2018/08/31 06:00 MHDA- 2018/08/31 06:01 PMCR- 2018/08/01 CRDT- 2018/08/31 06:00 PHST- 2018/08/31 06:00 [entrez] PHST- 2018/08/31 06:00 [pubmed] PHST- 2018/08/31 06:01 [medline] PHST- 2018/08/01 00:00 [pmc-release] AID - ophrp-09-0167 [pii] AID - 10.24171/j.phrp.2018.9.4.05 [doi] PST - ppublish SO - Osong Public Health Res Perspect. 2018 Aug;9(4):167-174. doi: 10.24171/j.phrp.2018.9.4.05.