PMID- 30160526
OWN - NLM
STAT- MEDLINE
DCOM- 20191108
LR  - 20230307
IS  - 1944-9097 (Electronic)
IS  - 0362-028X (Linking)
VI  - 81
IP  - 10
DP  - 2018 Oct
TI  - Determination and Quantitation of Residual Solvents in Natural Food Ingredients 
      Using a Static Headspace Gas Chromatography with Flame Ionization Detection and 
      Mass Spectrometric Detection Method.
PG  - 1573-1581
LID - 10.4315/0362-028X.JFP-18-142 [doi]
AB  - The determination of residual solvents is critical for quality control in food 
      production and manufacturing processes. A gas chromatographic and mass 
      spectrometric detection (MSD) method was developed and validated to complement 
      the static headspace flame ionization detection (FID) technique for 
      identification, confirmation, and quantitation of solvent residues in botanicals, 
      using Coffeeberry extract and pomegranate powder as test samples. Relative 
      standard deviations (RSDs) of less than 12% were obtained for residual solvents 
      in water and dimethyl sulfoxide. Coffeeberry extract supplemented with10 mug/g of 
      Residual Solvents Class 3 Mix showed MSD and FID recoveries mainly of 91 to 121% 
      and 77 to 110%, respectively, while those samples supplemented with 100 mug/g of 
      Residual Solvents Class 3 Mix displayed MSD and FID recoveries of 105 to 123% and 
      87 to 112%, respectively. For pomegranate samples supplemented with 10 mug/g of 
      Residual Solvents Class 3 Mix, MSD and FID recoveries of 95 to 124% and 72 to 
      151% were observed, respectively. Those samples supplemented with 100 mug/g of 
      Residual Solvents Class 3 Mix exhibited MSD and FID recoveries of 109 to 135% and 
      97 to 127%, respectively. Thus, the developed procedure was demonstrated to be 
      suitable for the analysis of residual solvents in natural food ingredients and is 
      expected to find numerous industrial applications (e.g., process control and 
      impurity detection in final products).
FAU - Al-Taher, Fadwa
AU  - Al-Taher F
AD  - 1 VDF FutureCeuticals, 2692 North State Route 1-17, Momence, Illinois 60954; and.
FAU - Nemzer, Boris
AU  - Nemzer B
AD  - 1 VDF FutureCeuticals, 2692 North State Route 1-17, Momence, Illinois 60954; and.
AD  - 2 Department of Food Science and Human Nutrition, University of Illinois at 
      Urbana-Champaign, 1201 West Gregory Drive, Urbana, Illinois 61801, USA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Food Prot
JT  - Journal of food protection
JID - 7703944
RN  - 0 (Food Ingredients)
RN  - 0 (Solvents)
SB  - IM
MH  - *Drug Contamination
MH  - Flame Ionization
MH  - *Food Ingredients/analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Solvents/*analysis
OTO - NOTNLM
OT  - Gas chromatography
OT  - Headspace
OT  - Ingredient
OT  - Residual solvent
EDAT- 2018/08/31 06:00
MHDA- 2019/11/09 06:00
CRDT- 2018/08/31 06:00
PHST- 2018/08/31 06:00 [pubmed]
PHST- 2019/11/09 06:00 [medline]
PHST- 2018/08/31 06:00 [entrez]
AID - S0362-028X(22)08753-1 [pii]
AID - 10.4315/0362-028X.JFP-18-142 [doi]
PST - ppublish
SO  - J Food Prot. 2018 Oct;81(10):1573-1581. doi: 10.4315/0362-028X.JFP-18-142.