PMID- 30172193
OWN - NLM
STAT- MEDLINE
DCOM- 20190912
LR  - 20211109
IS  - 1096-0953 (Electronic)
IS  - 0013-9351 (Print)
IS  - 0013-9351 (Linking)
VI  - 167
DP  - 2018 Nov
TI  - Persistent organic pollutants in fish from Charleston Harbor and tributaries, 
      South Carolina, United States: A risk assessment.
PG  - 598-613
LID - S0013-9351(18)30432-8 [pii]
LID - 10.1016/j.envres.2018.08.001 [doi]
AB  - Fish consumption is an important route of exposure to persistent organic 
      pollutants (POPs) in dolphins as well as humans. In order to assess the potential 
      risks associated with these contaminants, 39 whole fish and 37 fillets from fish 
      representing species consumed by dolphins and humans captured from Charleston 
      Harbor and tributaries, South Carolina, USA, were measured for a suite of POPs. 
      Polychlorinated biphenyls (PCBs) were the predominant contaminant with 
      concentrations ranging from 5.02 to 232.20 ng/g in whole fish and 
      5.42-131.95 ng/g in fillets (weight weight ww) followed by total organochlorine 
      pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs). Total POPs levels 
      varied by location and species with general trends indicating significantly 
      higher levels in fish from the Cooper (93.4 ng/g ww) and Ashley Rivers (56.2 ng/g 
      ww) compared to Charleston Harbor (31.6 ng/g ww). Mullet and spot were found to 
      have significantly higher PCBs, OCPs and total POPs, 2-3 times higher than red 
      drum; mullet were also significantly higher in OCPs compared to seatrout. PCB 
      concentrations in whole fish and fillets exceeded EPA human screening values for 
      cancer risk in all fish sampled. For PCBs in fillets, all samples had values of 
      maximum allowable meals per month that were less than the EPA, FDA guidelines for 
      recommended fish meals per month, suggesting lower (more stringent) allowable 
      fish meals per month. All fish exceeded PBDE wildlife values and all fish except 
      two exceeded the level where 95% of the dolphin population would have tissue 
      levels below the health effect threshold. Considering that POP concentrations in 
      fish potentially consumed by humans exceed human health effect thresholds levels, 
      consumption advisories should be considered as a prudent public health measure.
CI  - Copyright (c) 2018 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Fair, Patricia A
AU  - Fair PA
AD  - Department of Public Health Sciences, Medical University of South Carolina, 
      Charleston, SC 29412, USA; NOAA's Ocean Service, National Centers for Coastal 
      Ocean Science, Charleston, SC 29412, USA. Electronic address: fairp@musc.edu.
FAU - White, Natasha D
AU  - White ND
AD  - NOAA's Ocean Service, National Centers for Coastal Ocean Science, Charleston, SC 
      29412, USA.
FAU - Wolf, Beth
AU  - Wolf B
AD  - Department of Public Health Sciences, Medical University of South Carolina, 
      Charleston, SC 29412, USA.
FAU - Arnott, Stephen A
AU  - Arnott SA
AD  - Marine Resources Research Institute, South Carolina Department of Natural 
      Resources, Charleston, SC 29412, USA.
FAU - Kannan, Kurunthachalam
AU  - Kannan K
AD  - Wadsworth Center, New York State Department of Health, Empire State Plaza, PO Box 
      509, Albany, NY 12201-0509, USA.
FAU - Karthikraj, Rajendiran
AU  - Karthikraj R
AD  - Wadsworth Center, New York State Department of Health, Empire State Plaza, PO Box 
      509, Albany, NY 12201-0509, USA.
FAU - Vena, John E
AU  - Vena JE
AD  - Department of Public Health Sciences, Medical University of South Carolina, 
      Charleston, SC 29412, USA.
LA  - eng
GR  - P30 AR072582/AR/NIAMS NIH HHS/United States
GR  - P60 AR062755/AR/NIAMS NIH HHS/United States
GR  - UL1 RR029882/RR/NCRR NIH HHS/United States
GR  - UL1 TR001450/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20180807
PL  - Netherlands
TA  - Environ Res
JT  - Environmental research
JID - 0147621
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Water Pollutants, Chemical)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - *Environmental Pollutants
MH  - Fishes
MH  - Halogenated Diphenyl Ethers
MH  - Humans
MH  - *Hydrocarbons, Chlorinated
MH  - *Polychlorinated Biphenyls
MH  - Risk Assessment
MH  - South Carolina
MH  - United States
MH  - *Water Pollutants, Chemical
PMC - PMC6262760
MID - NIHMS996467
OTO - NOTNLM
OT  - Charleston Harbor
OT  - Dolphin
OT  - Human risk assessment
OT  - Marine fish
OT  - Persistent organic pollutants (POPs)
EDAT- 2018/09/02 06:00
MHDA- 2019/09/13 06:00
PMCR- 2019/11/01
CRDT- 2018/09/02 06:00
PHST- 2018/04/23 00:00 [received]
PHST- 2018/07/25 00:00 [revised]
PHST- 2018/08/02 00:00 [accepted]
PHST- 2018/09/02 06:00 [pubmed]
PHST- 2019/09/13 06:00 [medline]
PHST- 2018/09/02 06:00 [entrez]
PHST- 2019/11/01 00:00 [pmc-release]
AID - S0013-9351(18)30432-8 [pii]
AID - 10.1016/j.envres.2018.08.001 [doi]
PST - ppublish
SO  - Environ Res. 2018 Nov;167:598-613. doi: 10.1016/j.envres.2018.08.001. Epub 2018 
      Aug 7.