PMID- 30174036
OWN - NLM
STAT- MEDLINE
DCOM- 20190423
LR  - 20190423
IS  - 1873-7072 (Electronic)
IS  - 0308-8146 (Linking)
VI  - 270
DP  - 2019 Jan 1
TI  - Simultaneous determination of ten neonicotinoid insecticides and two metabolites 
      in honey and Royal-jelly by solid-phase extraction and liquid 
      chromatography-tandem mass spectrometry.
PG  - 204-213
LID - S0308-8146(18)31209-3 [pii]
LID - 10.1016/j.foodchem.2018.07.068 [doi]
AB  - An analytical method based on liquid chromatography-tandem mass spectrometry 
      (LC-MS/MS) method was developed for the first simultaneous determination of ten 
      neonicotinoid insecticides (pymetrozine, dinotefuran, nitenpyram, thiamethoxam, 
      flonicamid, imidacloprid, clothianidin, imidaclothiz, acetamiprid, thiacloprid) 
      and two metabolites (4-trifluoromethylnicotinamide and N-desmethylacetamiprid) in 
      honey and royal-jelly. The quantitative detection was performed by LC-MS/MS on 
      multiple reaction monitoring (MRM) mode under positive-ion electrospray 
      ionization. The isotope dilution internal standard method or external standard 
      method was used for quantitation analysis. The limits of quantification (LOQs), 
      calculated as 10 times the standard deviation, were 0.25-5.0 microg kg(-1) for ten 
      neonicotinoid insecticides and two metabolites. The average recoveries were in 
      the range of 72.8-106.5%, with relative standard deviations (RSDs) below 13.8%, 
      measured at three concentration levels. The developed method exhibits a high 
      sensitivity and suitable for the simultaneous determination of neonicotinoid 
      insecticides and metabolites in honey and royal-jelly.
CI  - Copyright (c) 2018. Published by Elsevier Ltd.
FAU - Hou, Jianbo
AU  - Hou J
AD  - Zhejiang Entry-Exit Inspection and Quarantine Bureau of P.R.C, Hangzhou 310016, 
      China.
FAU - Xie, Wen
AU  - Xie W
AD  - Zhejiang Entry-Exit Inspection and Quarantine Bureau of P.R.C, Hangzhou 310016, 
      China.
FAU - Hong, Deng
AU  - Hong D
AD  - Zhejiang Entry-Exit Inspection and Quarantine Bureau of P.R.C, Hangzhou 310016, 
      China.
FAU - Zhang, Wenhua
AU  - Zhang W
AD  - Zhejiang Entry-Exit Inspection and Quarantine Bureau of P.R.C, Hangzhou 310016, 
      China.
FAU - Li, Fei
AU  - Li F
AD  - Altay Entry-Exit Inspection and Quarantine Bureau of P.R.C, Altay 836500, China.
FAU - Qian, Yan
AU  - Qian Y
AD  - Zhejiang Lead Product Technic Co. Ltd., Hangzhou 310016, China.
FAU - Han, Chao
AU  - Han C
AD  - Wenzhou Entry-Exit Inspection and Quarantine Bureau of P.R.C, Wenzhou 325027, 
      China. Electronic address: chaohan96@hotmail.com.
LA  - eng
PT  - Journal Article
DEP - 20180719
PL  - England
TA  - Food Chem
JT  - Food chemistry
JID - 7702639
RN  - 0 (Insecticides)
RN  - 0 (Neonicotinoids)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Animals
MH  - Bees/*chemistry
MH  - Chromatography, High Pressure Liquid
MH  - Chromatography, Liquid
MH  - Honey/*analysis
MH  - Insecticides/analysis
MH  - Limit of Detection
MH  - Neonicotinoids/*analysis
MH  - Pesticide Residues/*analysis
MH  - Solid Phase Extraction
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Honey
OT  - LC-MS/MS
OT  - Metabolites
OT  - Neonicotinoid insecticides
OT  - Royal-jelly
EDAT- 2018/09/04 06:00
MHDA- 2019/04/24 06:00
CRDT- 2018/09/04 06:00
PHST- 2018/01/30 00:00 [received]
PHST- 2018/05/25 00:00 [revised]
PHST- 2018/07/11 00:00 [accepted]
PHST- 2018/09/04 06:00 [entrez]
PHST- 2018/09/04 06:00 [pubmed]
PHST- 2019/04/24 06:00 [medline]
AID - S0308-8146(18)31209-3 [pii]
AID - 10.1016/j.foodchem.2018.07.068 [doi]
PST - ppublish
SO  - Food Chem. 2019 Jan 1;270:204-213. doi: 10.1016/j.foodchem.2018.07.068. Epub 2018 
      Jul 19.