PMID- 30176762
OWN - NLM
STAT- MEDLINE
DCOM- 20210118
LR  - 20210118
IS  - 1476-4954 (Electronic)
IS  - 1476-4954 (Linking)
VI  - 33
IP  - 9
DP  - 2020 May
TI  - Chronic lung disease in preterm infants receiving various modes of noninvasive 
      ventilation at </=30 weeks' postmenstrual age.
PG  - 1466-1472
LID - 10.1080/14767058.2018.1519798 [doi]
AB  - Objective: To determine the incidence of chronic lung disease (CLD) in 
      mechanically ventilated infants who were born at <29 weeks' gestational age (GA), 
      extubated to continuous positive airway pressure (CPAP) or nasal intermittent 
      positive pressure ventilation (NIPPV), and treated with CPAP/NIPPV alone, changed 
      to heated humidified high flow nasal cannula (HHHFNC), or exposed to a 
      combination of CPAP/NIPPV and HHHFNC at </=30 weeks' postmenstrual age (PMA).Study 
      design: Retrospective cohort study of infants born at <29 weeks' GA admitted to 
      tertiary Canadian neonatal intensive care units between 2011 and 2015. Infants 
      were grouped according to the type of noninvasive ventilation they received at 
      </=30 weeks' PMA: CPAP/NIPPV alone, HHHFNC alone, or a combination of both.Results: 
      Of the 2378 eligible infants, 1091 (46%) were on CPAP/NIPPV alone, 173 (7.3%) 
      were on HHHFNC alone, and 1114 (47%) were on a combination of CPAP/NIPPV and 
      HHHFNC at </=30 weeks' PMA until weaned to room air or low flow nasal cannula. 
      After adjustment for confounders, infants in both the CPAP/NIPPV (odds ratio [95% 
      confidence interval]; 2.37 [1.18, 4.79]) and Combination (3.47 [2.06, 5.86]) 
      groups had higher odds of developing CLD than infants in the HHHFNC 
      group.Conclusions: Our results demonstrate that infants transitioned to HHHFNC 
      </=30 weeks' PMA after extubation to CPAP/NIPPV were associated with a lower odds 
      of CLD than infants maintained on CPAP/NIPPV or a combination of CPAP/NIPPV and 
      HHHFNC.
FAU - Leibel, Sandra L
AU  - Leibel SL
AD  - Department of Paediatrics, Mount Sinai Hospital, Toronto, Canada.
AD  - Department of Pediatrics, Division of Neonatology, Rady Children's Hospital, San 
      Diego, CA, USA.
FAU - Ye, Xiang Y
AU  - Ye XY
AD  - Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Canada.
FAU - Shah, Prakesh
AU  - Shah P
AD  - Department of Paediatrics, Mount Sinai Hospital, Toronto, Canada.
AD  - Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Canada.
AD  - Department of Paediatrics, University of Toronto, Toronto, Canada.
FAU - Shah, Vibhuti
AU  - Shah V
AD  - Department of Paediatrics, Mount Sinai Hospital, Toronto, Canada.
AD  - Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Canada.
AD  - Department of Paediatrics, University of Toronto, Toronto, Canada.
CN  - Canadian Neonatal Network
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20180926
PL  - England
TA  - J Matern Fetal Neonatal Med
JT  - The journal of maternal-fetal & neonatal medicine : the official journal of the 
      European Association of Perinatal Medicine, the Federation of Asia and Oceania 
      Perinatal Societies, the International Society of Perinatal Obstetricians
JID - 101136916
SB  - IM
MH  - Airway Extubation/methods
MH  - Continuous Positive Airway Pressure/adverse effects/statistics & numerical data
MH  - Female
MH  - Humans
MH  - Infant, Extremely Premature
MH  - Infant, Newborn
MH  - Intensive Care Units, Neonatal/statistics & numerical data
MH  - Intermittent Positive-Pressure Ventilation/adverse effects/statistics & numerical 
      data
MH  - Noninvasive Ventilation/*methods
MH  - Oxygen Inhalation Therapy/methods
MH  - Pregnancy
MH  - Respiratory Distress Syndrome, Newborn/*etiology/prevention & control
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Chronic lung disease
OT  - continuous positive airway pressure (CPAP)
OT  - heated humidified high flow nasal cannula (HHHFNC)
OT  - mechanical ventilation
OT  - preterm
EDAT- 2018/09/05 06:00
MHDA- 2021/01/20 06:00
CRDT- 2018/09/05 06:00
PHST- 2018/09/05 06:00 [pubmed]
PHST- 2021/01/20 06:00 [medline]
PHST- 2018/09/05 06:00 [entrez]
AID - 10.1080/14767058.2018.1519798 [doi]
PST - ppublish
SO  - J Matern Fetal Neonatal Med. 2020 May;33(9):1466-1472. doi: 
      10.1080/14767058.2018.1519798. Epub 2018 Sep 26.