PMID- 30177269
OWN - NLM
STAT- MEDLINE
DCOM- 20181011
LR  - 20181011
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1571
DP  - 2018 Oct 12
TI  - On-line combining monolith-based in-tube solid phase microextraction and 
      high-performance liquid chromatography- fluorescence detection for the sensitive 
      monitoring of polycyclic aromatic hydrocarbons in complex samples.
PG  - 29-37
LID - S0021-9673(18)30960-9 [pii]
LID - 10.1016/j.chroma.2018.07.077 [doi]
AB  - An automated and sensitive method, consisting of monolith-based in-tube 
      solid-phase microextraction (IT-SPME) coupled with high-performance liquid 
      chromatography-fluorescence detection (HPLC-FLD), was developed for the 
      monitoring of polycyclic aromatic hydrocarbons (PAHs) in water and milk samples. 
      To enrich PAHs, a new poly (9-vinylanthracene-co-ethylene dimethacrylate) 
      monolith was in-situ prepared and used as the adsorbent of IT-SPME. Various 
      parameters affecting the extraction performance were investigated thoroughly. 
      Under the optimal conditions, the synthesized monolith-based IT-SPME could enrich 
      target PAHs effectively through pi-pi and hydrophobic interactions. Moreover, the 
      developed on-line IT-SPME-HPLC-FLD method displayed satisfactory analytical 
      merits for PAHs. The limits of detection (S/N = 3) for PAHs in water and milk 
      samples were in the ranges of 0.017-0.23 ng/L and 0.10-2.36 ng/L, respectively. 
      The relative standard deviations (RSDs) for intra-day and inter-day precisions 
      with different spiked concentrations were below 9.8% and 11%, respectively. 
      Finally, the proposed method was successfully applied to quantify ultra-trace 
      target PAHs in water and milk samples. Several ng/L level PAHs were detected. 
      Spiked recoveries achieved for water and milk samples were in the ranges of 
      78.5-118% and 75.5-119%, respectively. The RSDs varied from 0.30% to 10% for all 
      analytes in all samples. In comparison with reported methods for the monitoring 
      of PAHs, the present method exhibits some merits such as high sensitivity, 
      automation of enrichment and determination procedure, low consumptions of sample 
      and organic solvent.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Pang, Jinling
AU  - Pang J
AD  - State Key Laboratory of Marine Environmental Science, Key Laboratory of the 
      Ministry of Education for Coastal and Wetland Ecosystem, College of the 
      Environment and Ecology, Xiamen University, China.
FAU - Yuan, Dongxing
AU  - Yuan D
AD  - State Key Laboratory of Marine Environmental Science, Key Laboratory of the 
      Ministry of Education for Coastal and Wetland Ecosystem, College of the 
      Environment and Ecology, Xiamen University, China.
FAU - Huang, Xiaojia
AU  - Huang X
AD  - State Key Laboratory of Marine Environmental Science, Key Laboratory of the 
      Ministry of Education for Coastal and Wetland Ecosystem, College of the 
      Environment and Ecology, Xiamen University, China. Electronic address: 
      hxj@xmu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20180727
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 0 (Solvents)
RN  - 0 (Water Pollutants, Chemical)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Animals
MH  - Chemistry Techniques, Analytical/*methods
MH  - *Chromatography, High Pressure Liquid
MH  - Fluorescence
MH  - Limit of Detection
MH  - Milk/*chemistry
MH  - Polycyclic Aromatic Hydrocarbons/*analysis
MH  - *Solid Phase Microextraction
MH  - Solvents/chemistry
MH  - Water/*chemistry
MH  - Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Adsorbent
OT  - Enrichment
OT  - In-tube solid phase microextraction
OT  - Monolith
OT  - Polycyclic aromatic hydrocarbons (PAHs)
EDAT- 2018/09/05 06:00
MHDA- 2018/10/12 06:00
CRDT- 2018/09/05 06:00
PHST- 2018/06/03 00:00 [received]
PHST- 2018/07/24 00:00 [revised]
PHST- 2018/07/27 00:00 [accepted]
PHST- 2018/09/05 06:00 [pubmed]
PHST- 2018/10/12 06:00 [medline]
PHST- 2018/09/05 06:00 [entrez]
AID - S0021-9673(18)30960-9 [pii]
AID - 10.1016/j.chroma.2018.07.077 [doi]
PST - ppublish
SO  - J Chromatogr A. 2018 Oct 12;1571:29-37. doi: 10.1016/j.chroma.2018.07.077. Epub 
      2018 Jul 27.