PMID- 30177972
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2297-1769 (Print)
IS  - 2297-1769 (Electronic)
IS  - 2297-1769 (Linking)
VI  - 5
DP  - 2018
TI  - The Effect of Low Protein Energy-Rich Diets on Plasma Hepatic Markers, Hepatic 
      Damage, and Discrimination Reversal Learning in Young Female Chicks.
PG  - 107
LID - 10.3389/fvets.2018.00107 [doi]
LID - 107
AB  - Consumption of low protein energy-rich (LPER) diets increases susceptibility to 
      metabolic disease in mammals, such as hepatic damage, and can have an adverse 
      effect on cognition. However, the effects of these diets on both physical and 
      mental welfare have not been investigated in domestic meat chickens. Female 
      chicks received a low protein energy-rich or a standard control diet from 21 to 
      51 days of age. The effects of these dietary manipulations on plasma hepatic 
      markers for liver damage, liver necropsy, and learning a visual discrimination 
      reversal task were assessed. Birds given access to LPER diets weighed less than 
      chicks that had access to the control diets. All chicks had post-mortem signs of 
      hepatic hemorrhage/increased liver color scores and aspartate aminotransferase 
      (AST) levels above 230 U/L indicative of hepatic damage in birds. The LPER diet 
      had no impact on the performance of female chicks when learning to distinguish 
      colors in a reversal visual discrimination task. The present study suggests that 
      liver damage does not become worse when feeding LPER or impact visual reversal 
      learning in female meat-type chickens. However, the high incidence of liver cell 
      damage/liver hemorrhage, and "abnormal" AST activities are of concern in female 
      broiler chicks across both diets, and suggests that the health of modern 
      meat-type genotypes needs to be improved.
FAU - Bona, Laura
AU  - Bona L
AD  - Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada.
FAU - van Staaveren, Nienke
AU  - van Staaveren N
AD  - Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada.
FAU - Pokharel, Bishwo Bandhu
AU  - Pokharel BB
AD  - Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada.
FAU - van Krimpen, Marinus
AU  - van Krimpen M
AD  - Wageningen UR Livestock Research, Wageningen, Netherlands.
FAU - Harlander-Matauschek, Alexandra
AU  - Harlander-Matauschek A
AD  - Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada.
LA  - eng
PT  - Journal Article
DEP - 20180523
PL  - Switzerland
TA  - Front Vet Sci
JT  - Frontiers in veterinary science
JID - 101666658
PMC - PMC6110198
OTO - NOTNLM
OT  - cognition
OT  - enzymes
OT  - female broiler
OT  - hepatic damage
OT  - welfare
EDAT- 2018/09/05 06:00
MHDA- 2018/09/05 06:01
PMCR- 2018/01/01
CRDT- 2018/09/05 06:00
PHST- 2018/03/06 00:00 [received]
PHST- 2018/05/01 00:00 [accepted]
PHST- 2018/09/05 06:00 [entrez]
PHST- 2018/09/05 06:00 [pubmed]
PHST- 2018/09/05 06:01 [medline]
PHST- 2018/01/01 00:00 [pmc-release]
AID - 371628 [pii]
AID - 10.3389/fvets.2018.00107 [doi]
PST - epublish
SO  - Front Vet Sci. 2018 May 23;5:107. doi: 10.3389/fvets.2018.00107. eCollection 
      2018.