PMID- 30178415 OWN - NLM STAT- MEDLINE DCOM- 20190108 LR - 20190108 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 25 IP - 31 DP - 2018 Nov TI - The concentration of heavy metals in noodle samples from Iran's market: probabilistic health risk assessment. PG - 30928-30937 LID - 10.1007/s11356-018-3030-y [doi] AB - In the current study, the concentration of heavy metals including lead (Pb), chromium (Cr), cadmium (Cd), and aluminum (Al) in commonly instant noodles consumed in Iran (either imported from other countries or produced in Iran) was investigated by acid digestion method followed by an inductively coupled plasma optical emission spectrometry system (ICP-OES). Also, the associated non-carcinogenic risk due to ingestion of heavy metals for adults and children was estimated by calculating percentile 95% target hazard quotient (THQ) in the Monte Carlo simulation (MCS) method. The average concentrations of Pb, Cr, Cd, and Al in Iranian instant noodle samples were measured as 1.21 +/- 0.81, 0.08 +/- 0.10, 0.03 +/- 0.06, and 9.15 +/- 4.82 (mg/kg) and in imported instant noodle samples were 1.00 +/- 0.61, 0.07 +/- 0.07, 0.04 +/- 0.03, and 15.90 +/- 0.93 (mg/kg), respectively. A significant difference (p value < 0.05) in the mean concentration of Pb, Cr, Cd, and Al of Iranian instant noodle and imported instant noodle samples was observed. Also, the concentration of Pb, Cr, Cd, and Al in all brands of instant noodle (0.025 mg/kg, 0.050 mg/kg, 0.003 mg/kg, and 0.237 mg/kg, respectively) surpassed the WHO-permitted limits for Pb, Cr, Cd, and Al. Percentile 95% of THQ of Pb, Cr, Cd, and Al for the adult consumers was calculated as 0.012, 0.000007, 0.010, and 1.789; while in the case of children, percentile 95% of THQ of Pb, Cr, Cd, and Al was defined as 0.044, 0.00023, 0.035, and 6.167, respectively. Health risk assessment indicated that both adults and children are at considerable non-carcinogenic health risk for Al (THQ > 1). Therefore, approaching the required strategies in order to reduce the concentration of heavy metals particularly Al in the instant noodle is recommended. FAU - Tajdar-Oranj, Behrouz AU - Tajdar-Oranj B AD - Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. AD - Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. FAU - Shariatifar, Nabi AU - Shariatifar N AD - Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. AD - Halal Research Center of IRI.FDA.MOH, Tehran, Iran. FAU - Alimohammadi, Mahmood AU - Alimohammadi M AD - Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. FAU - Peivasteh-Roudsari, Leila AU - Peivasteh-Roudsari L AD - Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. AD - Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. FAU - Khaniki, Gholamreza Jahed AU - Khaniki GJ AD - Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ghjahed@tums.ac.ir. FAU - Fakhri, Yadolah AU - Fakhri Y AD - Department of Environmental Health Engineering, School of Public Health, Student research committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran. FAU - Mousavi Khaneghah, Amin AU - Mousavi Khaneghah A AUID- ORCID: 0000-0001-5769-0004 AD - Department of Food Science, Faculty of Food Engineering, State University of Campinas (UNICAMP), Monteiro Lobato, 80, Caixa Postal: 6121, Campinas, Sao Paulo, 13083-862, Brazil. mousavi.amin@gmail.com. LA - eng GR - 3240274290/CNPq-TWAS Postgraduate Fellowship/ PT - Journal Article DEP - 20180904 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Dietary Carbohydrates) RN - 0 (Metals) SB - IM MH - Adult MH - Child MH - Dietary Carbohydrates/*analysis MH - Environmental Monitoring MH - Food Contamination/*analysis MH - Humans MH - Iran MH - Metals/*analysis MH - Monte Carlo Method MH - Risk Assessment OTO - NOTNLM OT - Heavy metals OT - ICP-OES OT - Instant noodle OT - Monte Carlo simulation, non-carcinogenic OT - Risk assessment EDAT- 2018/09/05 06:00 MHDA- 2019/01/09 06:00 CRDT- 2018/09/05 06:00 PHST- 2018/06/01 00:00 [received] PHST- 2018/08/20 00:00 [accepted] PHST- 2018/09/05 06:00 [pubmed] PHST- 2019/01/09 06:00 [medline] PHST- 2018/09/05 06:00 [entrez] AID - 10.1007/s11356-018-3030-y [pii] AID - 10.1007/s11356-018-3030-y [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2018 Nov;25(31):30928-30937. doi: 10.1007/s11356-018-3030-y. Epub 2018 Sep 4.