PMID- 30178769 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220412 IS - 0972-9941 (Print) IS - 1998-3921 (Electronic) IS - 1998-3921 (Linking) VI - 16 IP - 1 DP - 2020 Jan-Mar TI - Video-assisted mediastinoscopy is safe in patients taking antiplatelet or anticoagulant therapy. PG - 30-34 LID - 10.4103/jmas.JMAS_173_18 [doi] AB - BACKGROUND: The aim of this study was to report our experience with video-assisted mediastinoscopy (VAM) in patients taking antiplatelet (AP) or anticoagulant therapies focusing on perioperative complications (especially haemorrhagic). PATIENTS AND METHODS: We have done a retrospective study from a prospectively maintained database with diagnostic VAM (01/2008-06/2012). We included 54 patients with AP (41 patients - Group A) and anticoagulant (13 patients - Group B) therapies. The control group was formed by 263 patients (Group C). Data regarding the clinical records of the patients, operative time, per- and post-operative complications, total numbers of biopsies and the results of the pathologic examination were collected. We compared the groups A+B versus C, and then A versus C. Statistical differences were calculated by Chi-square test. RESULTS: In Group A, we had two minor complications: cardiac arrhythmia and peroperative minor haemorrhage. The mean operative time was 29 min and the mean post-operative stay was 1.08 days. In Group B, we had one minor complication: Peroperative minor haemorrhage. The mean operative time was 35 min and the mean post-operative stay was 1.07 days. In Group C, the mean operative time was 28 min. One death occurred (mortality rate of 0.38%) because of cardiac arrest at the induction of anaesthesia. One major complication occurred (severe respiratory insufficiency needing re-intubation) and eight minor complications. Morbidity rate was 2.28%. Mean post-operative stay was 1.14 days. No statistical difference was noted between groups. CONCLUSION: VAM can be safely performed in patients receiving AP or anticoagulant treatments. There is no increase in peroperative bleeding or post-operative compressive cervico-mediastinal haematoma. FAU - Cohen, Charlotte AU - Cohen C AD - Department of Thoracic Surgery, Pasteur Hospital, Nice, France. FAU - Pop, Daniel AU - Pop D AD - Department of Thoracic Surgery, Pasteur Hospital, Nice, France. FAU - Aze, Olivier AU - Aze O AD - Department of Thoracic Surgery, Pasteur Hospital, Nice, France. FAU - Venissac, Nicolas AU - Venissac N AD - Department of Thoracic Surgery, Pasteur Hospital, Nice, France. FAU - Mouroux, Jerome AU - Mouroux J AD - Department of Thoracic Surgery, Pasteur Hospital, Nice, France. LA - eng PT - Journal Article PL - India TA - J Minim Access Surg JT - Journal of minimal access surgery JID - 101228183 PMC - PMC6945347 OTO - NOTNLM OT - Lung neoplasm OT - minimally invasive OT - surgery COIS- None EDAT- 2018/09/05 06:00 MHDA- 2018/09/05 06:01 PMCR- 2020/01/01 CRDT- 2018/09/05 06:00 PHST- 2018/09/05 06:00 [pubmed] PHST- 2018/09/05 06:01 [medline] PHST- 2018/09/05 06:00 [entrez] PHST- 2020/01/01 00:00 [pmc-release] AID - 240461 [pii] AID - JMAS-16-30 [pii] AID - 10.4103/jmas.JMAS_173_18 [doi] PST - ppublish SO - J Minim Access Surg. 2020 Jan-Mar;16(1):30-34. doi: 10.4103/jmas.JMAS_173_18.