PMID- 30184749
OWN - NLM
STAT- MEDLINE
DCOM- 20181221
LR  - 20181221
IS  - 1873-0191 (Electronic)
IS  - 0928-4931 (Linking)
VI  - 92
DP  - 2018 Nov 1
TI  - Compressive characteristics of radially graded porosity scaffolds architectured 
      with minimal surfaces.
PG  - 254-267
LID - S0928-4931(17)33904-8 [pii]
LID - 10.1016/j.msec.2018.06.051 [doi]
AB  - Scaffolds with gradient pore characteristics have received a great deal of 
      attention as they can better mimic the structure of the native tissues and 
      concurrently meet both biological and mechanical requirements. In the present 
      study, the effects of porosity geometry and porosity gradient patterns on the 
      deformation mechanism and compressive mechanical properties of the structures 
      were investigated in the context of stretching (I-WP and P surfaces) versus 
      bending dominated (D surface) triply periodic minimal surface (TPMS) based 
      architectures. Different gradient patterns were found to significantly alter the 
      deformation mechanism. Radial gradient patterns (perpendicular to loading 
      direction) provide higher deformability while longitudinally graded scaffolds 
      suffer from low failure strain. In the stretching dominated architectures 
      vertical cracks propagated under compression due to the materials transverse 
      expansion under compression. Deformations in the bending dominated architectures, 
      however, were accompanied by a progressive collapse owing to the shearing of the 
      struts. In general, stretching dominated structures showed the higher mechanical 
      properties and provided more efficiency under mechanical loads. Finite Element 
      simulations also demonstrated a high capability for predicting the deformation as 
      well as mechanical responses (especially for elastic properties) and can be used 
      as a tool for designing multifunctional gradient porous scaffolds.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Afshar, M
AU  - Afshar M
AD  - Department of Mechanical Engineering, Shahid Rajaee Teacher Training University, 
      Tehran 16758-136, Iran. Electronic address: m.afshar6095@gmail.com.
FAU - Pourkamali Anaraki, A
AU  - Pourkamali Anaraki A
AD  - Department of Mechanical Engineering, Shahid Rajaee Teacher Training University, 
      Tehran 16758-136, Iran.
FAU - Montazerian, H
AU  - Montazerian H
AD  - Department of Mechanical Engineering, Shahid Rajaee Teacher Training University, 
      Tehran 16758-136, Iran; School of Engineering, University of British Columbia, 
      Kelowna, BC, Canada.
LA  - eng
PT  - Journal Article
DEP - 20180625
PL  - Netherlands
TA  - Mater Sci Eng C Mater Biol Appl
JT  - Materials science & engineering. C, Materials for biological applications
JID - 101484109
RN  - 0 (Plastics)
SB  - IM
MH  - *Compressive Strength
MH  - Computer Simulation
MH  - Plastics/chemistry
MH  - Porosity
MH  - Reproducibility of Results
MH  - Stress, Mechanical
MH  - Surface Properties
MH  - Tissue Scaffolds/*chemistry
OTO - NOTNLM
OT  - Additive manufacturing
OT  - Failure mechanisms
OT  - Gradient porosity
OT  - Mechanical characterization
OT  - Porous scaffolds
EDAT- 2018/09/07 06:00
MHDA- 2018/12/24 06:00
CRDT- 2018/09/07 06:00
PHST- 2017/09/27 00:00 [received]
PHST- 2018/05/02 00:00 [revised]
PHST- 2018/06/25 00:00 [accepted]
PHST- 2018/09/07 06:00 [entrez]
PHST- 2018/09/07 06:00 [pubmed]
PHST- 2018/12/24 06:00 [medline]
AID - S0928-4931(17)33904-8 [pii]
AID - 10.1016/j.msec.2018.06.051 [doi]
PST - ppublish
SO  - Mater Sci Eng C Mater Biol Appl. 2018 Nov 1;92:254-267. doi: 
      10.1016/j.msec.2018.06.051. Epub 2018 Jun 25.