PMID- 30187749 OWN - NLM STAT- MEDLINE DCOM- 20181015 LR - 20181015 IS - 1520-5118 (Electronic) IS - 0021-8561 (Linking) VI - 66 IP - 38 DP - 2018 Sep 26 TI - Synergistic Effect of a Thermal Reaction and Vacuum Dehydration on Improving Xylose-Phenylalanine Conversion to N-(1-Deoxy-d-xylulos-1-yl)-phenylalanine during an Aqueous Maillard Reaction. PG - 10077-10085 LID - 10.1021/acs.jafc.8b04448 [doi] AB - The synergistic effect of a thermal reaction and vacuum dehydration on the conversion of xylose (Xyl) and phenylalanine (Phe) to a Maillard-reaction intermediate (MRI) was researched. The yield of N-(1-deoxy-alpha-d-xylulos-1-yl)-phenylalanine was successfully improved and increased from 13.62 to 47.23% through the method combining a thermal reaction and vacuum dehydration. A dynamic process was involved in the transformation of Xyl and Phe (Xyl-Phe) to N-substituted d-xylosamine and in the transformation of N-substituted d-xylosamine to N-(1-deoxy-alpha-d-xylulos-1-yl)-phenylalanine during the initial stage of dehydration; then, only the transformation of N-substituted d-xylosamine to N-(1-deoxy-alpha-d-xylulos-1-yl)-phenylalanine occurred during the final stage. Furthermore, the MRI was prepared under optimized conditions (90 degrees C and pH 7.4), and the obtained MRI was characterized and confirmed by ESI mass spectrometry and NMR. FAU - Cui, Heping AU - Cui H AD - State Key Laboratory of Food Science and Technology, School of Food Science and Technology , Jiangnan University , 1800 Lihu Road , Wuxi , Jiangsu 214122 , PR China. AD - Department of Food Science , Rutgers University , 65 Dudley Road , New Brunswick , New Jersey 08901 , United States. FAU - Hayat, Khizar AU - Hayat K AD - Department of Food Science and Nutrition, College of Food and Agricultural Sciences , King Saud University , P.O. Box 2460, Riyadh 11451 , Saudi Arabia. FAU - Jia, Chengsheng AU - Jia C AD - State Key Laboratory of Food Science and Technology, School of Food Science and Technology , Jiangnan University , 1800 Lihu Road , Wuxi , Jiangsu 214122 , PR China. FAU - Duhoranimana, Emmanuel AU - Duhoranimana E AD - State Key Laboratory of Food Science and Technology, School of Food Science and Technology , Jiangnan University , 1800 Lihu Road , Wuxi , Jiangsu 214122 , PR China. FAU - Huang, Qingrong AU - Huang Q AUID- ORCID: 0000-0001-8637-0229 AD - Department of Food Science , Rutgers University , 65 Dudley Road , New Brunswick , New Jersey 08901 , United States. FAU - Zhang, Xiaoming AU - Zhang X AUID- ORCID: 0000-0002-1673-6026 AD - State Key Laboratory of Food Science and Technology, School of Food Science and Technology , Jiangnan University , 1800 Lihu Road , Wuxi , Jiangsu 214122 , PR China. FAU - Ho, Chi-Tang AU - Ho CT AUID- ORCID: 0000-0001-8273-2085 AD - Department of Food Science , Rutgers University , 65 Dudley Road , New Brunswick , New Jersey 08901 , United States. LA - eng PT - Journal Article DEP - 20180914 PL - United States TA - J Agric Food Chem JT - Journal of agricultural and food chemistry JID - 0374755 RN - 47E5O17Y3R (Phenylalanine) RN - A1TA934AKO (Xylose) SB - IM MH - Hot Temperature MH - Maillard Reaction MH - Phenylalanine/*chemistry MH - Spectrometry, Mass, Electrospray Ionization MH - Xylose/*chemistry OTO - NOTNLM OT - Maillard-reaction intermediate OT - N-(1-deoxy-d-xylulos-1-yl)-phenylalanine OT - synergistic effect OT - transformation EDAT- 2018/09/07 06:00 MHDA- 2018/10/16 06:00 CRDT- 2018/09/07 06:00 PHST- 2018/09/07 06:00 [pubmed] PHST- 2018/10/16 06:00 [medline] PHST- 2018/09/07 06:00 [entrez] AID - 10.1021/acs.jafc.8b04448 [doi] PST - ppublish SO - J Agric Food Chem. 2018 Sep 26;66(38):10077-10085. doi: 10.1021/acs.jafc.8b04448. Epub 2018 Sep 14.