PMID- 30190041 OWN - NLM STAT- MEDLINE DCOM- 20191010 LR - 20191010 IS - 1879-1360 (Electronic) IS - 0022-3999 (Linking) VI - 113 DP - 2018 Oct TI - Sleep quality and daytime sleepiness are not associated with cognition in heart failure. PG - 100-106 LID - S0022-3999(18)30166-1 [pii] LID - 10.1016/j.jpsychores.2018.08.003 [doi] AB - BACKGROUND: Individuals with heart failure (HF) exhibit comorbid impairments in both sleep and cognitive performance. Sleep quality has been associated with impaired cognitive performance in HF patients, but reports are inconsistent. In this study, we examined associations between sleep quality, daytime sleepiness, and cognitive function in HF. METHODS AND RESULTS: Participants were 267 (age = 69.1 +/- 9.3) mostly Caucasian (74.9%), male (59.6%) stable HF patients recruited from outpatient settings. This cross-sectional study was a secondary analysis of a prospective observational study. Cognitive function domains assessed included: global cognitive function, attention, memory, and executive function. Sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS), respectively. Separate multiple hierarchical linear regressions were conducted to determine associations between cognitive function and sleep quality and daytime sleepiness, after controlling for sex, New York Heart Association (NYHA) class, education, depressive symptoms, and medical comorbidities. Cognitive function was not associated with sleep quality or daytime sleepiness after alpha inflation corrections were applied. CONCLUSIONS: Cognitive function in HF is not associated with sleep quality or daytime sleepiness; other factors may exert greater influence on cognitive performance. CI - Copyright (c) 2018. Published by Elsevier Inc. FAU - Walter, Fawn A AU - Walter FA AD - Kent State University, Department of Psychological Sciences, P.O. Box 5190, Kent, OH 44240, USA. FAU - Ede, David AU - Ede D AD - Kent State University, Department of Psychological Sciences, P.O. Box 5190, Kent, OH 44240, USA. FAU - Hawkins, Misty A W AU - Hawkins MAW AD - Oklahoma State University, Department of Psychology, 116 N. Murray, Stillwater, OK 74078, USA. FAU - Dolansky, Mary A AU - Dolansky MA AD - Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA. FAU - Gunstad, John AU - Gunstad J AD - Kent State University, Department of Psychological Sciences, P.O. Box 5190, Kent, OH 44240, USA. FAU - Josephson, Richard AU - Josephson R AD - Harrington Heart & Vascular Institute, University Hospitals, Cleveland, OH, USA; College of Medicine, Case Western Reserve University, Cleveland, OH, USA. FAU - Moore, Shirley M AU - Moore SM AD - Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA. FAU - Hughes, Joel W AU - Hughes JW AD - Kent State University, Department of Psychological Sciences, P.O. Box 5190, Kent, OH 44240, USA. Electronic address: jhughes1@kent.edu. LA - eng SI - ClinicalTrials.gov/NCT01461629 GR - R01 HL096710/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20180810 PL - England TA - J Psychosom Res JT - Journal of psychosomatic research JID - 0376333 SB - IM MH - Aged MH - Cognitive Dysfunction/*psychology MH - Cross-Sectional Studies MH - Female MH - Heart Failure/*complications/psychology MH - Humans MH - Male MH - Prospective Studies MH - Sleep/*physiology MH - Sleep Wake Disorders/*complications/psychology MH - *Sleepiness OTO - NOTNLM OT - Cognition OT - Daytime sleepiness OT - Heart failure OT - Neuropsychological tests OT - Sleep quality EDAT- 2018/09/08 06:00 MHDA- 2019/10/11 06:00 CRDT- 2018/09/08 06:00 PHST- 2018/02/26 00:00 [received] PHST- 2018/08/07 00:00 [revised] PHST- 2018/08/08 00:00 [accepted] PHST- 2018/09/08 06:00 [entrez] PHST- 2018/09/08 06:00 [pubmed] PHST- 2019/10/11 06:00 [medline] AID - S0022-3999(18)30166-1 [pii] AID - 10.1016/j.jpsychores.2018.08.003 [doi] PST - ppublish SO - J Psychosom Res. 2018 Oct;113:100-106. doi: 10.1016/j.jpsychores.2018.08.003. Epub 2018 Aug 10.