PMID- 30193527
OWN - NLM
STAT- MEDLINE
DCOM- 20190509
LR  - 20190509
IS  - 0042-773X (Print)
IS  - 0042-773X (Linking)
VI  - 64
IP  - 5
DP  - 2018 Summer
TI  - Antithrombotics today.
PG  - 565-574
AB  - Over the last 10 years some new drugs affecting blood clotting - antithrombotics 
      - were invented. For more than half a century only warfarin and heparin were 
      available. A better understanding of the pathways involved in activation of blood 
      clotting, the links between these systems, and the impact of thrombosis on 
      inflammation, have led to identification of new targets and development of new 
      drugs, especially new antiplatelet drugs and anticoagulants. With the advent of 
      new drugs into clinical practice, treatment options of thrombotic complications 
      are expanding. However, it is always necessary to get familiar with the drug and 
      its properties and to know its limitations. This is the only way to offer 
      patients the best practices. Key words: anticoagulant - antithrombotic - Direct 
      Oral AntiCoagulant (DOAC) - laboratory monitoring - Low-Molecu-lar-Weight 
      Heparins (LMWH) - New Oral Anticoagulants/Non-vitamin K Oral AntiCoagulants 
      (NOAC) - unfractionated heparin (UFH) - warfarin.
FAU - Matyskova, Miloslava
AU  - Matyskova M
FAU - Michalcova, Jana
AU  - Michalcova J
FAU - Penka, Miroslav
AU  - Penka M
LA  - eng
PT  - Journal Article
TT  - Antitrombotika dnes.
PL  - Czech Republic
TA  - Vnitr Lek
JT  - Vnitrni lekarstvi
JID - 0413602
RN  - 0 (Anticoagulants)
RN  - 0 (Fibrinolytic Agents)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 5Q7ZVV76EI (Warfarin)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - *Anticoagulants/therapeutic use
MH  - Fibrinolytic Agents/therapeutic use
MH  - Heparin/therapeutic use
MH  - Heparin, Low-Molecular-Weight/therapeutic use
MH  - Humans
MH  - Warfarin/therapeutic use
EDAT- 2018/09/09 06:00
MHDA- 2019/05/10 06:00
CRDT- 2018/09/09 06:00
PHST- 2018/09/09 06:00 [entrez]
PHST- 2018/09/09 06:00 [pubmed]
PHST- 2019/05/10 06:00 [medline]
AID - 105477 [pii]
PST - ppublish
SO  - Vnitr Lek. 2018 Summer;64(5):565-574.