PMID- 30199892 OWN - NLM STAT- MEDLINE DCOM- 20190523 LR - 20200225 IS - 1833-3516 (Print) IS - 2209-1491 (Electronic) IS - 1833-3516 (Linking) VI - 48 IP - 3 DP - 2018 Sep 30 TI - A recurrent, ischaemic ileocolonic anastomosis ulcer refractory to surgery treated with hyperbaric oxygen. PG - 194-196 LID - 10.28920/dhm48.3.194-196 [doi] AB - A 54-year-old male had undergone right hemicolectomy and ileo-colonic anastomosis for carcinoma-in-situ found at colonoscopy. Eighteen months later, he presented with a lower gastrointestinal bleed from an anastomotic ulcer, treated with resection of the anastomotic site and ileo-sigmoid anastomosis. In the ensuing 12 months, he had three episodes of haematochezia. Colonoscopy revealed a 12 mm anastomotic ulcer necessitating a further colonic resection and re-anastomosis. Two-years later, he presented with iron deficiency anaemia. He preferred expectant management and received ten iron-infusions over the subsequent four years. Thereafter, he developed painless haematochezia. Colonoscopy showed a 15 mm linear ulcer with mild ooze at the anastomosis. Histology was consistent with an ischaemic ulcer; there was no evidence of recurrence of carcinoma-in-situ. The ulcer remained refractory to endoscopic and medical treatment, as seen at three follow-up colonoscopies. Hyperbaric oxygen treatment (HBOT) was offered and he received 30 sessions over six weeks. Colonoscopy at HBOT completion revealed healing of the ulcer. The patient had no further overt bleeding and serum ferritin has continued to rise spontaneously over 12 months follow-up. CI - Copyright: This article is the copyright of the authors who grant Diving and Hyperbaric Medicine a non-exclusive licence to publish the article in electronic and other forms. FAU - Pateria, Puraskar AU - Pateria P AD - Corresponding author: Department of Gastroenterology and Hepatology, Service 4, CD09, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia 6150, Puraskar.Pateria@health.wa.gov.au. FAU - Chong, Andre AU - Chong A AD - Department of Gastroenterology and Hepatology, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia 6150. LA - eng PT - Case Reports PL - Australia TA - Diving Hyperb Med JT - Diving and hyperbaric medicine JID - 101282742 SB - IM MH - Anastomosis, Surgical/*adverse effects MH - Colon MH - Humans MH - *Hyperbaric Oxygenation MH - Ischemia MH - Male MH - Middle Aged MH - *Ulcer/therapy PMC - PMC6205864 OTO - NOTNLM OT - Case reports OT - Chronic wounds OT - Gastrointestinal tract COIS- Conflicts of interest: nil. EDAT- 2018/09/11 06:00 MHDA- 2019/05/24 06:00 PMCR- 2019/09/26 CRDT- 2018/09/11 06:00 PHST- 2018/07/26 00:00 [received] PHST- 2018/08/06 00:00 [accepted] PHST- 2018/09/11 06:00 [entrez] PHST- 2018/09/11 06:00 [pubmed] PHST- 2019/05/24 06:00 [medline] PHST- 2019/09/26 00:00 [pmc-release] AID - 10.28920/dhm48.3.194-196 [doi] PST - ppublish SO - Diving Hyperb Med. 2018 Sep 30;48(3):194-196. doi: 10.28920/dhm48.3.194-196.