PMID- 30203530 OWN - NLM STAT- MEDLINE DCOM- 20190412 LR - 20190412 IS - 1755-3768 (Electronic) IS - 1755-375X (Linking) VI - 97 IP - 2 DP - 2019 Mar TI - Comparison of corneal biomechanical changes after refractive surgery by noncontact tonometry: small-incision lenticule extraction versus flap-based refractive surgery - a systematic review. PG - 127-136 LID - 10.1111/aos.13906 [doi] AB - Corneal refractive surgery disrupts corneal integrity and reduces biomechanical stability in consequence of the beneficial refractive alteration. The minimal invasive cap-based refractive procedure, small-incision lenticule extraction (SMILE), has been proposed to affect corneal integrity less than flap-based procedures, due to the fibre-sparing incision of the strong anterior corneal lamellae. Flap-based procedures include laser-assisted in situ keratomileusis (LASIK), femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and femtosecond lenticule extraction (FLEx). The purpose of this systematic review was to evaluate corneal biomechanical changes by noncontact air pulse tonometry after treatment of myopia/myopic astigmatism with SMILE compared to flap-based refractive surgery. A total of 220 publications were identified through a systematic search in PubMed and Embase. Two levels of screening identified nine studies (three randomised controlled trials (RCT) and six nonrandomised clinical trials) eligible for the review. All the nonrandomised clinical trials were graded to have an overall serious risk of bias. Measurements with the Corvis ST were not included in any of the eligible studies. The RCTs found no statistical significant differences between SMILE or flap-based procedures concerning corneal hysteresis (CH) or corneal resistance factor (CRF), as measured with the Ocular Response Analyzer. However, a greater reduction in CRF and CH was found in the flap-based group in five and two of the nonrandomised studies, respectively. The findings in this review illustrate that the presumed biomechanical advantages of a cap-based small incision could not be demonstrated in existing studies and by commercially available technology. However, studies with lower levels of evidence suggest less affection of corneal viscoelastic properties after SMILE when evaluating corneal stability by noncontact tonometry. CI - (c) 2018 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. FAU - Raevdal, Pernille AU - Raevdal P AD - Department of Ophthalmology, Odense University Hospital, Odense, Denmark. AD - Research Unit of Ophthalmology, University of Southern Denmark, Odense, Denmark. FAU - Grauslund, Jakob AU - Grauslund J AUID- ORCID: 0000-0001-5019-0736 AD - Department of Ophthalmology, Odense University Hospital, Odense, Denmark. AD - Research Unit of Ophthalmology, University of Southern Denmark, Odense, Denmark. FAU - Vestergaard, Anders Hojslet AU - Vestergaard AH AUID- ORCID: 0000-0003-1687-4899 AD - Department of Ophthalmology, Odense University Hospital, Odense, Denmark. AD - Research Unit of Ophthalmology, University of Southern Denmark, Odense, Denmark. LA - eng PT - Journal Article PT - Systematic Review DEP - 20180910 PL - England TA - Acta Ophthalmol JT - Acta ophthalmologica JID - 101468102 SB - IM MH - Biomechanical Phenomena MH - Cornea/pathology/*physiopathology/surgery MH - Corneal Topography MH - Humans MH - Keratomileusis, Laser In Situ/*methods MH - Myopia/physiopathology/*surgery MH - *Surgical Flaps MH - Visual Acuity OTO - NOTNLM OT - air pulse tonometry, myopia OT - corneal biomechanics OT - femtosecond laser OT - femtosecond lenticule extraction OT - laser in situ keratomileusis OT - small-incision lenticule extraction OT - systematic review EDAT- 2018/09/12 06:00 MHDA- 2019/04/13 06:00 CRDT- 2018/09/12 06:00 PHST- 2018/05/02 00:00 [received] PHST- 2018/08/04 00:00 [accepted] PHST- 2018/09/12 06:00 [pubmed] PHST- 2019/04/13 06:00 [medline] PHST- 2018/09/12 06:00 [entrez] AID - 10.1111/aos.13906 [doi] PST - ppublish SO - Acta Ophthalmol. 2019 Mar;97(2):127-136. doi: 10.1111/aos.13906. Epub 2018 Sep 10.