PMID- 30204487
OWN - NLM
STAT- MEDLINE
DCOM- 20190522
LR  - 20190522
IS  - 1556-8342 (Electronic)
IS  - 1556-8253 (Linking)
VI  - 13
IP  - 9
DP  - 2018 Nov
TI  - Comparison of Breast Milk Compositions Among Mothers Delivering 
      Small-for-Gestational Age, Appropriate-for-Gestational Age, and 
      Large-for-Gestational Age Infants.
PG  - 627-630
LID - 10.1089/bfm.2018.0043 [doi]
AB  - OBJECTIVES: The aim of this study was to compare the breast milk compositions of 
      mothers who delivered babies in three different birth weight categories. 
      MATERIALS AND METHODS: We collected 75 breast milk samples from mothers of 
      small-for-gestational age (SGA), appropriate-for-gestational age (AGA), and 
      large-for-gestational age (LGA) term infants (25 per group) on the 11th-28th day 
      postpartum using a manual or electric breast pump. Homogenized samples were 
      analyzed using a mid-infrared human milk analyzer within 2 hours of collection, 
      and protein, carbohydrate (CHO), fat, and energy levels were compared. RESULTS: 
      Of 75 participants (median maternal age: 29 years), there was a significant 
      difference in maternal body mass index (BMI), gestational age, and birth weight 
      among the three groups. However, we found no significant variation in breast milk 
      true protein, crude protein, fat, or energy. The CHO composition of breast milk 
      in mothers of SGA infants (7.1 g/100 mL, range: 6.6-7.3 g/100 mL) was 
      significantly lower than that in the AGA (7.3 g/100 mL, range: 7.1-7.5 g/100 mL) 
      and LGA (7.2 g/100 mL, range: 6.7-7.4 g/100 mL) groups. After post hoc multiple 
      comparison, only CHO levels between the SGA and AGA groups were significantly 
      different (p = 0.025), whereas no significant correlation was found between 
      maternal BMI, gestational age, and CHO. CONCLUSIONS: The CHO component in breast 
      milk from mothers of SGA infants was significantly lower compared with the AGA 
      and LGA groups, but with no clinical significance. Breast milk compositions of 
      mothers of LGA infants were comparable to those of SGA and AGA infants. 
      Therefore, fetal growth status does not significantly influence maternal breast 
      milk nutrients.
FAU - Phattraprayoon, Nanthida
AU  - Phattraprayoon N
AD  - 1 Department of Pediatrics, Queen Sirikit National Institute of Child Health, 
      Neonatal-Perinatal Medicine, College of Medicine, Rangsit University , Bangkok, 
      Thailand .
FAU - Kraisonsin, Nadaprapai
AU  - Kraisonsin N
AD  - 2 Queen Sirikit National Institute of Child Health , Bangkok, Thailand .
FAU - Kanjanapattanakul, Wiboon
AU  - Kanjanapattanakul W
AD  - 1 Department of Pediatrics, Queen Sirikit National Institute of Child Health, 
      Neonatal-Perinatal Medicine, College of Medicine, Rangsit University , Bangkok, 
      Thailand .
LA  - eng
PT  - Journal Article
DEP - 20180911
PL  - United States
TA  - Breastfeed Med
JT  - Breastfeeding medicine : the official journal of the Academy of Breastfeeding 
      Medicine
JID - 101260777
SB  - IM
MH  - Adult
MH  - *Birth Weight
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Female
MH  - Fetal Macrosomia
MH  - *Gestational Age
MH  - Humans
MH  - Infant, Newborn
MH  - Infant, Small for Gestational Age
MH  - Lactation
MH  - Male
MH  - Milk, Human/*chemistry
MH  - Thailand
MH  - Young Adult
OTO - NOTNLM
OT  - appropriate-for-gestational age infants
OT  - breast milk compositions
OT  - large-for-gestational age infants
OT  - small-for-gestational age infants
EDAT- 2018/09/12 06:00
MHDA- 2019/05/23 06:00
CRDT- 2018/09/12 06:00
PHST- 2018/09/12 06:00 [pubmed]
PHST- 2019/05/23 06:00 [medline]
PHST- 2018/09/12 06:00 [entrez]
AID - 10.1089/bfm.2018.0043 [doi]
PST - ppublish
SO  - Breastfeed Med. 2018 Nov;13(9):627-630. doi: 10.1089/bfm.2018.0043. Epub 2018 Sep 
      11.