PMID- 30207083
OWN - NLM
STAT- MEDLINE
DCOM- 20190722
LR  - 20210109
IS  - 2162-3279 (Electronic)
VI  - 8
IP  - 10
DP  - 2018 Oct
TI  - Analysis of Codman microcerebrospinal fluid shunt.
PG  - e01002
LID - 10.1002/brb3.1002 [doi]
LID - e01002
AB  - INTRODUCTION: Ventriculo-peritoneal cerebrospinal fluid (CSF) shunt is the most 
      common method of treating pediatric hydrocephalus. The Codman microadjustable 
      valve (CMAV) is a CSF shunt constructed for children. The objective of the study 
      was (a) to analyze complications after insertion of a CMAV shunt in hydrocephalic 
      children, (b) to analyze complications after replacing a CMAV by an adult-type 
      Codman Hakim adjustable valve shunt (CHAV), and to (c) analyze the in vitro 
      characteristics of the CMAV shunt and correlate the findings with the clinical 
      performance of the shunt. METHODS: A retrospective study analyzed a cohort of 
      hydrocephalic children who had received a CMAV shunt and later replaced by a CHAV 
      shunt. We report on the complications that resulted from replacing the CMAV with 
      the CHAV. We tested six CMAV shunts with or without an antisiphon device (ASD) in 
      which opening pressure, resistance, sensitivity to abdominal pressure, ASD 
      position dependency, and function were determined. The test results were 
      correlated with the clinical performance of the shunt in the retrospective study. 
      RESULTS: Thirty-seven children (19 boys, 18 girls) were identified. Within the 
      first month after shunt placement, a total of 10 patients (27%) developed 
      complications including infections, hygromas, and shunt dysfunction. Shunt 
      survival varied from 1 week to 145 months. Over the 10-year follow-up period, 13 
      children had their shunts replaced, six of them with a CHAV without any further 
      complications. A bench test of the CMAV was done to test whether the opening 
      pressure was in agreement with the manufacturer's specifications. Our results 
      were generally in agreement with specifications stated by the manufacturer. 
      CONCLUSION: Replacing a CMAV with a CHAV was well tolerated by the patients. 
      Bench test results were generally in agreement with manufacturers specifications. 
      Replacing a CMAV with a CHAV in pediatric hydrocephalus patients can be 
      accomplished safely.
CI  - (c) 2018 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.
FAU - Sandvig, Axel
AU  - Sandvig A
AUID- ORCID: 0000-0003-0087-7075
AD  - Department of Pharmacology and Clinical Neurosciences, Division of Neuro, Head 
      and Neck, Umea University, Umea, Sweden.
AD  - Department of Neuromedicine and Movement Science, Norwegian University of Science 
      and Technology, Trondheim, Norway.
FAU - Arnell, Kai
AU  - Arnell K
AD  - Department of Surgery, Umea University, Umea, Sweden.
FAU - Malm, Jan
AU  - Malm J
AD  - Department of Pharmacology and Clinical Neurosciences, Division of Neuro, Head 
      and Neck, Umea University, Umea, Sweden.
FAU - Eklund, Anders
AU  - Eklund A
AD  - Department of Radiation Sciences, Umea University, Umea, Sweden.
FAU - Koskinen, Lars-Owe D
AU  - Koskinen LD
AD  - Department of Pharmacology and Clinical Neurosciences, Division of Neuro, Head 
      and Neck, Umea University, Umea, Sweden.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180911
PL  - United States
TA  - Brain Behav
JT  - Brain and behavior
JID - 101570837
SB  - IM
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Hydrocephalus/*surgery
MH  - Infant
MH  - Male
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Ventriculoperitoneal Shunt/*adverse effects
PMC - PMC6192409
OTO - NOTNLM
OT  - cerebrospinal fluid
OT  - clinical retrospective study
EDAT- 2018/09/13 06:00
MHDA- 2019/07/23 06:00
PMCR- 2018/09/11
CRDT- 2018/09/13 06:00
PHST- 2017/07/30 00:00 [received]
PHST- 2018/03/18 00:00 [revised]
PHST- 2018/04/15 00:00 [accepted]
PHST- 2018/09/13 06:00 [pubmed]
PHST- 2019/07/23 06:00 [medline]
PHST- 2018/09/13 06:00 [entrez]
PHST- 2018/09/11 00:00 [pmc-release]
AID - BRB31002 [pii]
AID - 10.1002/brb3.1002 [doi]
PST - ppublish
SO  - Brain Behav. 2018 Oct;8(10):e01002. doi: 10.1002/brb3.1002. Epub 2018 Sep 11.