PMID- 30210544 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1687-8787 (Print) IS - 1687-8795 (Electronic) IS - 1687-8787 (Linking) VI - 2018 DP - 2018 TI - Experimental Investigations into the Mechanical, Tribological, and Corrosion Properties of Hybrid Polymer Matrix Composites Comprising Ceramic Reinforcement for Biomedical Applications. PG - 9283291 LID - 10.1155/2018/9283291 [doi] LID - 9283291 AB - Hybrid polymer matrix composites (HPMC) are prominent material for the formation of biomaterial and offer various advantages such as low cost, high strength, and the fact that they are easy to manufacture. However, they are associated with low mechanical (low hardness) and tribological properties (high wear rate). The average hip joint load fluctuates between three to five times of the body weight during jumping and jogging and depends on various actions relating to body positions. Alternate bone and prosthesis material plays a critical role in attaining strength as it determines the method of load transferred to the system. The material property called modulus of elasticity is an important design variable during the selection of the geometry and design methodology. The present work is demonstrated on how to improve the properties of high-density polyethylene (HDPE) substantially by the addition of bioceramic fillers such as titanium oxide (TiO(2)) and alumina (Al(2)O(3)). The volume fractions of Al(2)O(3) and TiO(2) are limited to 20% and 10%, respectively. Samples were fabricated as per ASTM standards using an injection moulding machine and various properties such as mechanical (tensile, flexural, and impact), tribological (hardness, wear), and corrosion including SEM, density, and fractography analysis studied. Experimental results revealed that an injection moulding process is suitable for producing defect-free mould HPMC. HPMC comprising 70% HDPE/20% Al(2)O(3)/10% TiO(2) has proved biocompatible and a substitute for biomaterial. A substantial increase in the mechanical and tribological properties and full resistance to corrosion makes HPMC suitable for use in orthopaedic applications such as human bone replacement, bone fixation plates, hip joint replacement, bone cement, and bone graft in bone surgery. FAU - Yunus, Mohammed AU - Yunus M AUID- ORCID: 0000-0003-1116-4978 AD - Department of Mechanical Engineering, College of Engineering and Islamic Architecture, Umm Al-Qura University, Al-Abdiah, Makkah 24231, Saudi Arabia. FAU - Alsoufi, Mohammad S AU - Alsoufi MS AD - Department of Mechanical Engineering, College of Engineering and Islamic Architecture, Umm Al-Qura University, Al-Abdiah, Makkah 24231, Saudi Arabia. LA - eng PT - Journal Article DEP - 20180823 PL - United States TA - Int J Biomater JT - International journal of biomaterials JID - 101519099 PMC - PMC6126091 EDAT- 2018/09/14 06:00 MHDA- 2018/09/14 06:01 PMCR- 2018/08/23 CRDT- 2018/09/14 06:00 PHST- 2018/02/28 00:00 [received] PHST- 2018/07/10 00:00 [revised] PHST- 2018/08/07 00:00 [accepted] PHST- 2018/09/14 06:00 [entrez] PHST- 2018/09/14 06:00 [pubmed] PHST- 2018/09/14 06:01 [medline] PHST- 2018/08/23 00:00 [pmc-release] AID - 10.1155/2018/9283291 [doi] PST - epublish SO - Int J Biomater. 2018 Aug 23;2018:9283291. doi: 10.1155/2018/9283291. eCollection 2018.