PMID- 30211684
OWN - NLM
STAT- MEDLINE
DCOM- 20190108
LR  - 20230928
IS  - 1305-3612 (Electronic)
IS  - 1305-3825 (Print)
IS  - 1305-3825 (Linking)
VI  - 24
IP  - 5
DP  - 2018 Sep
TI  - ARFI shear-wave elastography with simulation of acute urinary tract obstruction 
      in an ex vivo porcine kidney model.
PG  - 308-315
LID - 10.5152/dir.2018.17353 [doi]
AB  - METHODS: A total of 20 heparinized pig kidneys were investigated at 10 
      intrapelvic hydrostatic pressure steps (0-90 mmHg). SWE (ARFI; Virtual TouchTM 
      IQ, Siemens) measurements were taken at three different measuring regions and in 
      two measuring sequences using a linear ultrasonography probe (9L4, Siemens). 
      Median values of 10 shear-wave speed (SWS) measurements were calculated for each 
      pressure step. Logarithmic transformed median SWS values were analyzed in a 
      linear mixed model. RESULTS: SWS increased significantly with increasing 
      intrapelvic pressure. Median SWS for all kidneys in both measuring sequences and 
      all measuring regions was 1.47 m/s (interquartile range [IQR], 0.38 m/s) at 0 
      mmHg, 1.94 m/s (IQR, 0.42 m/s) at 30 mmHg, 2.07 m/s (IQR, 0.43 m/s) at 60 mmHg, 
      2.24 m/s (IQR, 0.49 m/s) at 90 mmHg. The correlation between pelvic pressure 
      increase and median SWS values for the central parenchyma was significantly 
      higher compared with the peripheral parenchyma. CONCLUSION: Acutely increased 
      renal pelvic pressure correlates with increasing SWS values in ARFI elastography 
      in an ex vivo porcine kidney model.
FAU - Muttray, Jens
AU  - Muttray J
AD  - Division of Pediatric Radiology, Clinic of Diagnostic and Interventional 
      Radiology University of Heidelberg School of Medicine, Heidelberg, Germany.
FAU - Mehrabi, Arianeb
AU  - Mehrabi A
AD  - Department of Visceral and Transplantation Surgery , University of Heidelberg 
      School of Medicine, Heidelberg, Germany.
FAU - Hafezi, Mohammadreza
AU  - Hafezi M
AD  - Department of Visceral and Transplantation Surgery ,University of Heidelberg 
      School of Medicine, Heidelberg, Germany.
FAU - Saffari, Arash
AU  - Saffari A
AD  - Department of Visceral and Transplantation Surgery ,University of Heidelberg 
      School of Medicine, Heidelberg, German.
FAU - Bui-Ta, Thi Thanh Tam
AU  - Bui-Ta TTT
AD  - Division of Pediatric Radiology, Clinic of Diagnostic and Interventional 
      Radiology, University of Heidelberg School of Medicine, Heidelberg, Germany.
FAU - Meyburg, Jochen
AU  - Meyburg J
AD  - Clinic I, Center for Pediatrics and Adolescent Medicine, University of Heidelberg 
      School of Medicine, Heidelberg, Germany.
FAU - Wuhl, Elke
AU  - Wuhl E
AD  - Division of Pediatric Nephrology, Clinic I, Center for Pediatrics and Adolescent 
      Medicine, University of Heidelberg School of Medicine, Heidelberg, Germany.
FAU - Schenk, Jens Peter
AU  - Schenk JP
AD  - Division of Pediatric Radiology, Clinic of Diagnostic and Interventional 
      Radiology University of Heidelberg School of Medicine, Heidelberg, Germany.
LA  - eng
PT  - Journal Article
PL  - Turkey
TA  - Diagn Interv Radiol
JT  - Diagnostic and interventional radiology (Ankara, Turkey)
JID - 101241152
SB  - IM
MH  - Animals
MH  - Elasticity Imaging Techniques/*methods
MH  - Kidney/*anatomy & histology/diagnostic imaging/physiopathology
MH  - Models, Animal
MH  - Parenchymal Tissue/*diagnostic imaging/physiopathology
MH  - Pelvis/physiology
MH  - Pressure
MH  - Swine
MH  - Ultrasonography/methods
MH  - Urinary Tract/*pathology
PMC - PMC6135057
COIS- Conflict of interest disclosure The authors declared no conflicts of interest.
EDAT- 2018/09/14 06:00
MHDA- 2019/01/09 06:00
PMCR- 2018/09/01
CRDT- 2018/09/14 06:00
PHST- 2018/09/14 06:00 [entrez]
PHST- 2018/09/14 06:00 [pubmed]
PHST- 2019/01/09 06:00 [medline]
PHST- 2018/09/01 00:00 [pmc-release]
AID - dir-24-5-308 [pii]
AID - 10.5152/dir.2018.17353 [doi]
PST - ppublish
SO  - Diagn Interv Radiol. 2018 Sep;24(5):308-315. doi: 10.5152/dir.2018.17353.