PMID- 30214186
OWN - NLM
STAT- MEDLINE
DCOM- 20190123
LR  - 20190123
IS  - 1178-2005 (Electronic)
IS  - 1176-9106 (Print)
IS  - 1176-9106 (Linking)
VI  - 13
DP  - 2018
TI  - Determining the minimally important difference in quadriceps strength in 
      individuals with COPD using a fixed dynamometer.
PG  - 2685-2693
LID - 10.2147/COPD.S161342 [doi]
AB  - BACKGROUND: Measurement of quadriceps muscular force is recommended in 
      individuals with COPD, notably during a pulmonary rehabilitation program (PRP). 
      However, the tools used to measure quadriceps maximal voluntary contraction 
      (QMVC) and the clinical relevance of the results, as well as their interpretation 
      for a given patient, remain a matter of debate. The objective of this study was 
      to estimate the minimally important difference (MID) of QMVC using a fixed 
      dynamometer in individuals with COPD undergoing a PRP. METHODS: Individuals with 
      COPD undergoing a PRP were included in this study. QMVC was measured using a 
      dynamometer (MicroFET2) fixed on a rigid support according to a standard-ized 
      methodology. Exercise capacity was measured by 6-minute walk distance (6MWD) and 
      evaluation of quality of life with St George's respiratory questionnaire (SGRQ) 
      and Hospital Anxiety and Depression Scale (HADS) total scores. All measures were 
      obtained at baseline and the end of the PRP. The MID was calculated using 
      distribution-based methods. RESULTS: A total of 157 individuals with COPD (age 
      62.9+/-9.0 years, forced expiratory volume in 1 second 47.3%+/-18.6% predicted) were 
      included in this study. At the end of the PRP, the patients had improved their 
      quadriceps force significantly by 8.9+/-15.6 Nm (P<0.001), as well as 6MWD by 42+/-50 
      m (P<0.001), SGRQ total score by -9+/-17 (P<0.001) and HADS total score by -3+/-6 
      (P<0.001). MID estimation using distribution-based analysis was 7.5 Nm by 
      empirical rule effect size and 7.8 Nm by Cohen's effect size. CONCLUSION: 
      Measurement of QMVC using a fixed dynamometer is a simple and valuable tool 
      capable of assessing improvement in quadriceps muscle force after a PRP. We 
      suggest an MID of 7.5 Nm to identify beneficial changes after a PRP intervention.
FAU - Vaidya, Trija
AU  - Vaidya T
AD  - Laboratory MOVE (EA6314), Faculty of Sport Sciences, University of Poitiers, 
      Poitiers, France.
AD  - Laboratory "Movement, Interactions, Performance" (EA4334), Faculty of Sport 
      Sciences, University of Nantes, Nantes, France, arnaud.chambellan@chu-nantes.fr.
FAU - Beaumont, Marc
AU  - Beaumont M
AD  - Pulmonary Rehabilitation unit, Morlaix Hospital Centre, Morlaix, France.
AD  - EA3878 (G.E.T.B.O), CHU Brest, Brest, France.
FAU - de Bisschop, Claire
AU  - de Bisschop C
AD  - Laboratory MOVE (EA6314), Faculty of Sport Sciences, University of Poitiers, 
      Poitiers, France.
FAU - Bazerque, Lucie
AU  - Bazerque L
AD  - Institute of Physical Education and Sports Sciences (IFEPSA), Universite 
      Catholique de l'Ouest (UCO), Angers, France.
FAU - Le Blanc, Camille
AU  - Le Blanc C
AD  - Physical Medicine and Rehabilitation Department, University Hospital of Nantes, 
      Nantes, France.
FAU - Vincent, Anne
AU  - Vincent A
AD  - Respiratory Rehabilitation Service, la Tourmaline, UGECAM, Nantes, France.
FAU - Ouksel, Hakima
AU  - Ouksel H
AD  - Dept of Pulmonary Medicine, Angers University Hospital, Angers, France.
FAU - Chambellan, Arnaud
AU  - Chambellan A
AD  - Laboratory "Movement, Interactions, Performance" (EA4334), Faculty of Sport 
      Sciences, University of Nantes, Nantes, France, arnaud.chambellan@chu-nantes.fr.
AD  - l'institut du Thorax, University Hospital of Nantes, Nantes, France, 
      arnaud.chambellan@chu-nantes.fr.
LA  - eng
PT  - Journal Article
DEP - 20180830
PL  - New Zealand
TA  - Int J Chron Obstruct Pulmon Dis
JT  - International journal of chronic obstructive pulmonary disease
JID - 101273481
SB  - IM
MH  - Female
MH  - Forced Expiratory Volume
MH  - France
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscle Strength/*physiology
MH  - *Muscle Strength Dynamometer
MH  - Pulmonary Disease, Chronic Obstructive/*physiopathology/rehabilitation
MH  - Quadriceps Muscle/*physiology
MH  - Quality of Life
MH  - Surveys and Questionnaires
PMC - PMC6124469
OTO - NOTNLM
OT  - COPD
OT  - QMVC
OT  - dynamometer
OT  - muscular dysfunction
OT  - pulmonary rehabilitation
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2018/09/15 06:00
MHDA- 2019/01/24 06:00
PMCR- 2018/08/30
CRDT- 2018/09/15 06:00
PHST- 2018/09/15 06:00 [entrez]
PHST- 2018/09/15 06:00 [pubmed]
PHST- 2019/01/24 06:00 [medline]
PHST- 2018/08/30 00:00 [pmc-release]
AID - copd-13-2685 [pii]
AID - 10.2147/COPD.S161342 [doi]
PST - epublish
SO  - Int J Chron Obstruct Pulmon Dis. 2018 Aug 30;13:2685-2693. doi: 
      10.2147/COPD.S161342. eCollection 2018.