PMID- 30215951
OWN - NLM
STAT- MEDLINE
DCOM- 20190801
LR  - 20190801
IS  - 1532-0650 (Electronic)
IS  - 0002-838X (Linking)
VI  - 98
IP  - 1
DP  - 2018 Jul 1
TI  - Allergy Testing: Common Questions and Answers.
PG  - 34-39
AB  - An estimated 10% to 30% of the global population has an allergic disease. 
      Clinical presentations of allergic diseases, respiratory infections, and 
      autoimmune conditions have similar features. Allergy and immunologic testing can 
      help clarify the diagnosis and guide treatment. Immediate immunoglobulin E (IgE) 
      and delayed T cell-mediated reactions are the main types of allergic responses. 
      The allergens suspected in an immediate IgE-mediated response are identified 
      through serum IgE-specific antibody or skin testing. For patients with an 
      inhalant allergy, skin or IgE-specific antibody testing is preferred. In patients 
      with food allergies, eliminating the suspected allergenic food from the diet is 
      the initial treatment. If this is ineffective, IgE-specific antibody or skin 
      testing can exclude allergens. An oral food challenge should be performed to 
      confirm the diagnosis. Patients with an anaphylactic reaction to an insect sting 
      should undergo IgE-specific antibody or skin testing. Skin testing for penicillin 
      has a high negative predictive value and can help when penicillin administration 
      is indicated and there are limited alternatives. Testing for other drug allergies 
      has less well-determined sensitivity and specificity, but can guide the 
      diagnosis. Patch testing can help identify the allergen responsible for contact 
      dermatitis.
FAU - Chang, Ku-Lang
AU  - Chang KL
AD  - University of Florida College of Medicine, Gainesville, FL, USA.
FAU - Guarderas, Juan Carlos
AU  - Guarderas JC
AD  - University of Florida College of Medicine, Gainesville, Fl, USA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am Fam Physician
JT  - American family physician
JID - 1272646
RN  - 37341-29-0 (Immunoglobulin E)
MH  - *Education, Medical, Continuing
MH  - Food Hypersensitivity/*diagnosis
MH  - Humans
MH  - Immunoglobulin E/*analysis
MH  - Immunologic Tests/*methods/*standards
MH  - Male
MH  - *Practice Guidelines as Topic
MH  - Skin Tests/*methods/*standards
EDAT- 2018/09/15 06:00
MHDA- 2019/08/02 06:00
CRDT- 2018/09/15 06:00
PHST- 2018/09/15 06:00 [entrez]
PHST- 2018/09/15 06:00 [pubmed]
PHST- 2019/08/02 06:00 [medline]
AID - d13504 [pii]
PST - ppublish
SO  - Am Fam Physician. 2018 Jul 1;98(1):34-39.