PMID- 30219601
OWN - NLM
STAT- MEDLINE
DCOM- 20190404
LR  - 20190404
IS  - 1878-108X (Electronic)
IS  - 0166-2236 (Linking)
VI  - 41
IP  - 11
DP  - 2018 Nov
TI  - New Roles for an Ancient Factor.
PG  - 765-767
LID - S0166-2236(18)30237-6 [pii]
LID - 10.1016/j.tins.2018.08.012 [doi]
AB  - In 1996, Hyejin Kang and Erin Schuman, in search of new functions for the 
      secreted growth factor brain-derived neurotrophic factor (BDNF), identified the 
      protein synthesis requirement of BDNF in regulating synaptic plasticity. This 
      landmark paper identified one of the first tractable pathways in the quest to 
      dissect the complex process of synaptic remodeling and revealed the critical role 
      for this neurotrophin in regulating long-term memory.
CI  - Copyright (c) 2018. Published by Elsevier Ltd.
FAU - Lee, Francis S
AU  - Lee FS
AD  - Department of Psychiatry, Weill Cornell Medical College, New York, NY, USA; Brain 
      and Mind Research Institute, Weill Cornell Medical College, New York, NY, USA. 
      Electronic address: fslee@med.cornell.edu.
FAU - Hempstead, Barbara L
AU  - Hempstead BL
AD  - Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, 
      USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. 
      Electronic address: blhempst@med.cornell.edu.
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20180912
PL  - England
TA  - Trends Neurosci
JT  - Trends in neurosciences
JID - 7808616
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*metabolism
MH  - Long-Term Potentiation/physiology
MH  - Long-Term Synaptic Depression/physiology
MH  - Neuronal Plasticity/*physiology
MH  - Protein Biosynthesis/physiology
MH  - Rats
MH  - Synapses/*metabolism
MH  - Synaptic Transmission/*physiology
OTO - NOTNLM
OT  - BDNF
OT  - long-term potentiation
EDAT- 2018/09/17 06:00
MHDA- 2019/04/05 06:00
CRDT- 2018/09/17 06:00
PHST- 2018/08/16 00:00 [received]
PHST- 2018/08/16 00:00 [accepted]
PHST- 2018/09/17 06:00 [pubmed]
PHST- 2019/04/05 06:00 [medline]
PHST- 2018/09/17 06:00 [entrez]
AID - S0166-2236(18)30237-6 [pii]
AID - 10.1016/j.tins.2018.08.012 [doi]
PST - ppublish
SO  - Trends Neurosci. 2018 Nov;41(11):765-767. doi: 10.1016/j.tins.2018.08.012. Epub 
      2018 Sep 12.