PMID- 30230920 OWN - NLM STAT- MEDLINE DCOM- 20190730 LR - 20190730 IS - 1715-5320 (Electronic) IS - 1715-5312 (Linking) VI - 44 IP - 4 DP - 2019 Apr TI - Prescribing high-intensity interval exercise by RPE in individuals with type 2 diabetes: metabolic and hemodynamic responses. PG - 348-356 LID - 10.1139/apnm-2018-0371 [doi] AB - We tested the hypothesis that rating of perceived exertion (RPE) is a tool as efficient as the heart rate (HR) response to the cardiopulmonary exercise test (CPX) for prescribing and self-regulating high-intensity interval exercise (HIIE), and that metabolic and hemodynamic response to HIIE is superior than to continuous moderate-intensity exercise (MICE) in individuals with type 2 diabetes mellitus (T2DM). Eleven participants (age = 52.3 +/- 3 years) underwent HIIE prescribed and self-regulated by RPE (HIIE(RPE); 25 min), HIIE prescribed and regulated by an individual's HR response to CPX (HIIE(HR); 25 min), MICE prescribed and self-regulated by RPE (30 min) and control (30 min of seated resting) intervention in random order. HR, blood pressure (BP), capillary glucose, endothelial reactivity, and carotid-femoral pulse wave velocity were assessed before, immediately after, and 45 min after each intervention. Exercise HR, speed, and distance were measured during exercise sessions. Twenty-four-hour ambulatory BP was measured after each intervention. Exercise HR, speed, and distance were similar between HIIE(RPE) and HIIE(HR). BP response was not different among HIIE(RPE), HIIE(HR), and MICE. Capillary glycaemia reduction was greater (P < 0.05) after HIIE(RPE) (48.6 +/- 9.6 mg/dL) and HIIE(HR) (47.2 +/- 9.5 mg/dL) than MICE (29.5 +/- 11.5 mg/dL). Reduction (P < 0.05) in 24-h (6.7 +/- 2.2 mm Hg) and tendency toward reduction (P = 0.06) in daytime systolic (7.0 +/- 2.5 mm Hg) ambulatory BP were found only after HIIE(RPE). These results suggest that HIIE is superior to MICE for reducing glycaemia and ambulatory BP, and that the 6-20 RPE scale is a useful tool for prescribing and self-regulating HIIE in individuals with T2DM. FAU - Viana, Ariane Aparecida AU - Viana AA AD - a Sao Paulo State University - UNESP, School of Sciences, Physical Education Department, Exercise and Chronic Disease Research Laboratory, Bauru 17033-360, Brazil. FAU - Fernandes, Bianca AU - Fernandes B AD - a Sao Paulo State University - UNESP, School of Sciences, Physical Education Department, Exercise and Chronic Disease Research Laboratory, Bauru 17033-360, Brazil. FAU - Alvarez, Cristian AU - Alvarez C AD - b Family Healthcare Center Tomas Rojas, Los Lagos, Chile; Universidad de Los Lagos, Department of Physical Activity Sciences, Osorno 5290000, Chile. FAU - Guimaraes, Guilherme Veiga AU - Guimaraes GV AD - c University of Sao Paulo, School of Medicine, Heart Institute, Sao Paulo 05403-900, Brazil. FAU - Ciolac, Emmanuel Gomes AU - Ciolac EG AD - a Sao Paulo State University - UNESP, School of Sciences, Physical Education Department, Exercise and Chronic Disease Research Laboratory, Bauru 17033-360, Brazil. LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20180919 PL - Canada TA - Appl Physiol Nutr Metab JT - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JID - 101264333 RN - 0 (Biomarkers) RN - 0 (Blood Glucose) MH - Adult MH - Aged MH - Biomarkers/blood MH - Blood Glucose/*metabolism MH - Blood Pressure MH - Blood Pressure Monitoring, Ambulatory MH - Brazil MH - Cross-Over Studies MH - Diabetes Mellitus, Type 2/blood/diagnosis/physiopathology/*therapy MH - *Energy Metabolism MH - Exercise Test MH - Female MH - Heart Rate MH - *Hemodynamics MH - *High-Intensity Interval Training MH - Humans MH - Male MH - Middle Aged MH - *Physical Exertion MH - Pulse Wave Analysis MH - Time Factors MH - Treatment Outcome MH - Vascular Stiffness OTO - NOTNLM OT - arterial stiffness OT - blood pressure OT - capillary glycaemia OT - diabete de type 2 [Traduit par la Redaction] OT - exercice par intervalle d'intensite elevee OT - glycemie capillaire OT - high-intensity interval exercise OT - pression sanguine OT - rating of perceived exertion OT - rigidite arterielle OT - type 2 diabetes mellitus OT - evaluation de l'effort percu EDAT- 2018/09/20 06:00 MHDA- 2019/07/31 06:00 CRDT- 2018/09/20 06:00 PHST- 2018/09/20 06:00 [pubmed] PHST- 2019/07/31 06:00 [medline] PHST- 2018/09/20 06:00 [entrez] AID - 10.1139/apnm-2018-0371 [doi] PST - ppublish SO - Appl Physiol Nutr Metab. 2019 Apr;44(4):348-356. doi: 10.1139/apnm-2018-0371. Epub 2018 Sep 19.