PMID- 30235592
OWN - NLM
STAT- MEDLINE
DCOM- 20190403
LR  - 20190403
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 646
DP  - 2019 Jan 1
TI  - Mandibular shape in farmed Arctic foxes (Vulpes lagopus) exposed to persistent 
      organic pollutants.
PG  - 1063-1068
LID - S0048-9697(18)32862-6 [pii]
LID - 10.1016/j.scitotenv.2018.07.367 [doi]
AB  - We investigated if dietary exposure to persistent organic pollutants (POPs) 
      affect mandibular asymmetry and periodontal disease in paired male-siblings of 
      Arctic foxes (Vulpes lagopus). During ontogeny, one group of siblings was exposed 
      to the complexed POP mixture in naturally contaminated minke whale (Balaenoptere 
      acutorostarta) blubber (n = 10), while another group was given wet feed based on 
      pig (Sus scrofa) fat as a control (n = 11). The  summation operatorPOP concentrations were 
      802 ng/g ww in the whale-based feed compared to 24 ng/g ww in the control diet. 
      We conducted a two-dimensional geometric morphometric (GM) analysis of mandibular 
      shape and asymmetry in the foxes and compared the two groups. The analyses showed 
      that directional asymmetry was higher than fluctuating asymmetry in both groups 
      and that mandibular shape differed significantly between the exposed and control 
      group based on discriminant function analysis (T(2) = 58.52, p = 0.04, 1000 
      permutations). We also found a non-significantly higher incidence of periodontal 
      disease (two-way ANOVA: p = 0.43) and greater severity of sub-canine alveolar 
      bone deterioration similar to periodontitis (two-way ANOVA: p = 0.3) in the 
      POP-exposed group. Based on these results, it is possible that dietary exposure 
      to a complexed POP mixture lead to changes in jaw morphology in Arctic foxes. 
      This study suggests that extrinsic factors, such as dietary exposure to POPs, may 
      affect mandibular shape and health in a way that could be harmful to wild Arctic 
      populations. Therefore, further studies using GM analysis as an alternative to 
      traditional morphometric methods should be conducted for wild Arctic fox 
      populations exposed to environmental contaminants.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Bradley, Madison M
AU  - Bradley MM
AD  - Department of Archaeology and Anthropology, University of Calgary, 2500 
      University Drive N.W., Calgary, Alberta T2N 1N4, Canada. Electronic address: 
      mmbradle@ucalgary.ca.
FAU - Perra, Megan
AU  - Perra M
AD  - Independent Researcher, 97231 Portland, OR, USA.
FAU - Ahlstrom, Oystein
AU  - Ahlstrom O
AD  - Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian 
      University of Life Sciences, P.O. Box 5003, NO-1433 As, Norway. Electronic 
      address: oystein.ahlstrom@nmbu.no.
FAU - Jenssen, Bjorn M
AU  - Jenssen BM
AD  - Department of Biology, Norwegian University of Science and Technology, NO-7491 
      Trondheim, Norway; Department of Arctic Technology, The University Centre in 
      Svalbard, PO Box 156, NO-9171 Longyearbyen, Norway; Aarhus University, Faculty of 
      Science and Technology, Department of Bioscience, Arctic Research Centre, P.O. 
      Box 358, DK-4000 Roskilde, Denmark. Electronic address: 
      bjorn.munro.jenssen@ntnu.no.
FAU - Jorgensen, Even H
AU  - Jorgensen EH
AD  - Department of Arctic and Marine Biology, UiT the Arctic University of Norway, N, 
      NO-9037 Tromso, Norway. Electronic address: even.jorgensen@uit.no.
FAU - Fuglei, Eva
AU  - Fuglei E
AD  - Norwegian Polar Institute, Fram Centre, NO-9296 Tromso, Norway. Electronic 
      address: eva.fuglei@npolar.no.
FAU - Muir, Derek C G
AU  - Muir DCG
AD  - Aquatic Contaminants Research Division, Environment and Climate Change Canada, 
      Burlington L7S 1A1, ON, Canada. Electronic address: derek.muir@canada.ca.
FAU - Sonne, Christian
AU  - Sonne C
AD  - Aarhus University, Faculty of Science and Technology, Department of Bioscience, 
      Arctic Research Centre, P.O. Box 358, DK-4000 Roskilde, Denmark. Electronic 
      address: cs@bios.au.dk.
LA  - eng
PT  - Journal Article
DEP - 20180726
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Adipose Tissue
MH  - Animals
MH  - Arctic Regions
MH  - Diet
MH  - Dogs
MH  - Environmental Pollutants/*toxicity
MH  - Foxes/*anatomy & histology/physiology
MH  - Male
MH  - Mandible/*anatomy & histology/drug effects
MH  - Swine
OTO - NOTNLM
OT  - Balaenoptera acutorostrata
OT  - Fluctuating asymmetry, geometric morphometric
OT  - GM
OT  - OCs
OT  - Organochlorines
OT  - PCB
OT  - POPs
OT  - Periodontal disease, Minke whale
OT  - Polychlorinated biphenyls
EDAT- 2018/09/22 06:00
MHDA- 2019/04/04 06:00
CRDT- 2018/09/22 06:00
PHST- 2018/05/28 00:00 [received]
PHST- 2018/07/25 00:00 [revised]
PHST- 2018/07/26 00:00 [accepted]
PHST- 2018/09/22 06:00 [entrez]
PHST- 2018/09/22 06:00 [pubmed]
PHST- 2019/04/04 06:00 [medline]
AID - S0048-9697(18)32862-6 [pii]
AID - 10.1016/j.scitotenv.2018.07.367 [doi]
PST - ppublish
SO  - Sci Total Environ. 2019 Jan 1;646:1063-1068. doi: 
      10.1016/j.scitotenv.2018.07.367. Epub 2018 Jul 26.