PMID- 3023699
OWN - NLM
STAT- MEDLINE
DCOM- 19870114
LR  - 20200724
IS  - 0022-538X (Print)
IS  - 1098-5514 (Electronic)
IS  - 0022-538X (Linking)
VI  - 61
IP  - 1
DP  - 1987 Jan
TI  - A new common integration region (int-3) for mouse mammary tumor virus on mouse 
      chromosome 17.
PG  - 218-20
AB  - Mus musculus subsp. musculus (Czech II) mammary tumor DNA frequently contains an 
      integrated proviral genome of the mouse mammary tumor virus (MMTV) within a 
      specific 0.5-kilobase-pair region of the cellular genome (designated int-3). 
      Viral integration at this site results in activation of expression of an adjacent 
      cellular gene. We mapped int-3 to mouse chromosome 17 by analysis of 
      PstI-restricted cellular DNAs from mouse-hamster somatic cell hybrids. 
      Restriction analysis of cellular DNA from (C3H/OuJ X Czech II) X Czech II 
      backcross mice established the gene order T-H-2-int-3. These results demonstrated 
      that the int-3 locus is distinct from two other common integration regions for 
      mouse mammary tumor virus (designated int-1 and int-2) in mammary tumor DNA and 
      suggest that several cellular genes may be at risk for virally induced activation 
      during mammary tumor development.
FAU - Gallahan, D
AU  - Gallahan D
FAU - Kozak, C
AU  - Kozak C
FAU - Callahan, R
AU  - Callahan R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Virol
JT  - Journal of virology
JID - 0113724
RN  - EC 3.1.21.- (DNA Restriction Enzymes)
SB  - IM
MH  - Animals
MH  - Chromosome Mapping
MH  - Chromosomes/physiology
MH  - Crosses, Genetic
MH  - DNA Restriction Enzymes
MH  - Genes, Viral
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Mice
PMC - PMC255246
EDAT- 1987/01/01 00:00
MHDA- 1987/01/01 00:01
PMCR- 1987/01/01
CRDT- 1987/01/01 00:00
PHST- 1987/01/01 00:00 [pubmed]
PHST- 1987/01/01 00:01 [medline]
PHST- 1987/01/01 00:00 [entrez]
PHST- 1987/01/01 00:00 [pmc-release]
AID - 10.1128/JVI.61.1.218-220.1987 [doi]
PST - ppublish
SO  - J Virol. 1987 Jan;61(1):218-20. doi: 10.1128/JVI.61.1.218-220.1987.