PMID- 30237707 OWN - NLM STAT- MEDLINE DCOM- 20190123 LR - 20190123 IS - 1178-2005 (Electronic) IS - 1176-9106 (Print) IS - 1176-9106 (Linking) VI - 13 DP - 2018 TI - A comparative study of the five-repetition sit-to-stand test and the 30-second sit-to-stand test to assess exercise tolerance in COPD patients. PG - 2833-2839 LID - 10.2147/COPD.S173509 [doi] AB - PURPOSE: The sit-to-stand test (STST) has been used to evaluate the exercise tolerance of patients with COPD. However, mutual comparisons to predict poor exercise tolerance have been hindered by the variety of STST modes used in previous studies, which also did not consider patients' subjective perceptions of different STST modes. Our aim was to compare the five-repetition sit-to-stand test (5STS) with the 30-second sit-to-stand test (30STS) for predicting poor performance in the six-minute walking test and to evaluate patients' subjective perceptions to determine the optimal mode for clinical practice. PATIENTS AND METHODS: Patients with stable COPD performed 5STS, 30STS and the 6MWT and then evaluated their feelings about the two STST modes by Borg dyspnea score and a questionnaire. Moreover, we collected data through the pulmonary function test, mMRC dyspnea score, COPD assessment test and quadriceps muscle strength (QMS). A receiver operating characteristic curve analysis of the 5STS and 30STS results was used to predict 6-minute walk distance (6MWD) <350 m. RESULTS: The final analysis included 128 patients. Similar moderate correlations were observed between 6MWT and 5STS (r=-0.508, P<0.001) and between 6MWT and 30STS (r=0.528, P<0.001), and there were similar correlations between QMS and 5STS (r=-0.401, P<0.001) and between QMS and 30STS (r=0.398, P<0.001). The 5STS and 30STS score cutoffs produced sensitivity, specificity and positive and negative predictive values of 76.0%, 62.8%, 56.7% and 80.3% (5STS) and 62.0%, 75.0%, 62.0% and 75.0% (30STS), respectively, for predicting poor 6MWT performance. The 5STS exhibited obvious superiority in terms of the completion rate and the subjective feelings of the participants. CONCLUSION: As a primary screening test for predicting poor 6MWD, the 5STS is similar to the 30STS in terms of sensitivity and specificity, but the 5STS has a better patient experience. FAU - Zhang, Qin AU - Zhang Q AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Li, Yan-Xia AU - Li YX AD - Department of Respiratory Medicine, First Hospital of Dalian Medical University, Dalian, China. FAU - Li, Xue-Lian AU - Li XL AD - Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China. FAU - Yin, Yan AU - Yin Y AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Li, Rui-Lan AU - Li RL AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Qiao, Xin AU - Qiao X AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Li, Wei AU - Li W AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Ma, Hai-Feng AU - Ma HF AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Ma, Wen-Hui AU - Ma WH AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Han, Yu-Feng AU - Han YF AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Zeng, Guang-Qiao AU - Zeng GQ AD - State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China, zgqiao@vip.163.com. FAU - Wang, Qiu-Yue AU - Wang QY AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Kang, Jian AU - Kang J AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. FAU - Hou, Gang AU - Hou G AD - Institute of Respiratory Disease, First Hospital of China Medical University, Shenyang, China, hou_gang@163.com. LA - eng PT - Comparative Study PT - Journal Article DEP - 20180910 PL - New Zealand TA - Int J Chron Obstruct Pulmon Dis JT - International journal of chronic obstructive pulmonary disease JID - 101273481 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - China MH - Dyspnea/physiopathology MH - Exercise Test/*methods/statistics & numerical data MH - Exercise Tolerance/*physiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Muscle Strength MH - Perception MH - Pulmonary Disease, Chronic Obstructive/*physiopathology MH - Quadriceps Muscle/physiopathology MH - ROC Curve MH - *Sitting Position MH - *Standing Position MH - Time Factors MH - Walk Test/methods PMC - PMC6136403 OTO - NOTNLM OT - COPD OT - exercise endurance OT - sit-to-stand test OT - six-minute walk test COIS- Disclosure The authors report no conflicts of interest in this work. EDAT- 2018/09/22 06:00 MHDA- 2019/01/24 06:00 PMCR- 2018/09/10 CRDT- 2018/09/22 06:00 PHST- 2018/09/22 06:00 [entrez] PHST- 2018/09/22 06:00 [pubmed] PHST- 2019/01/24 06:00 [medline] PHST- 2018/09/10 00:00 [pmc-release] AID - copd-13-2833 [pii] AID - 10.2147/COPD.S173509 [doi] PST - epublish SO - Int J Chron Obstruct Pulmon Dis. 2018 Sep 10;13:2833-2839. doi: 10.2147/COPD.S173509. eCollection 2018.