PMID- 30238590
OWN - NLM
STAT- MEDLINE
DCOM- 20200610
LR  - 20200610
IS  - 1542-4758 (Electronic)
IS  - 1492-7535 (Linking)
VI  - 23
IP  - 1
DP  - 2019 Jan
TI  - Investigation of small intestinal lesions in dialysis patients using capsule 
      endoscopy.
PG  - 77-80
LID - 10.1111/hdi.12683 [doi]
AB  - INTRODUCTION: Although gastrointestinal hemorrhage is an important complication 
      for dialysis patients, the details of many points remain unclear with regard to 
      small intestinal lesions. METHODS: Capsule endoscopy was performed in fecal 
      occult blood-positive dialysis (n =16) and non-dialysis (n = 20) patients after 
      upper and lower gastrointestinal endoscopies failed to reveal hemorrhagic 
      lesions. FINDINGS: Erosive lesions were observed in 50.0% (8/16) and 25.0% (5/20) 
      of the dialysis and non-dialysis groups, respectively. Vascular lesions were 
      observed in 62.5% (10/16) and 25.0% (5/20), respectively. Vascular lesions were 
      observed at a significantly higher rate in the dialysis patients (P = 0.041), but 
      no significant difference was noted in erosive lesions (P = 0.188). Of patients 
      taking proton pump inhibitor (PPI), Non-Steroidal Anti-Inflammatory Drugs, and 
      antiplatelet drugs, only oral PPI administration was associated with vascular 
      lesions (P = 0.02). DISCUSSION: In dialysis patients, vascular lesions are the 
      most common among small intestinal lesions, suggesting that they may have caused 
      previously unexplained gastrointestinal hemorrhage in dialysis patients. It was 
      also suggested that the frequent use of PPI may be a cause of small intestinal 
      lesions.
CI  - (c) 2018 International Society for Hemodialysis.
FAU - Nakajima, Fumitaka
AU  - Nakajima F
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Furumatsu, Yoshiyuki
AU  - Furumatsu Y
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Yurugi, Takatomi
AU  - Yurugi T
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Amari, Yoshifumi
AU  - Amari Y
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Iida, Takeshi
AU  - Iida T
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Fukui, Takayuki
AU  - Fukui T
AD  - Department of Nephrology, Moriguchi Keijinkai Hospital, Moriguchi, Osaka, Japan.
FAU - Kuramoto, Takanori
AU  - Kuramoto T
AD  - Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan.
LA  - eng
PT  - Journal Article
DEP - 20180920
PL  - Canada
TA  - Hemodial Int
JT  - Hemodialysis international. International Symposium on Home Hemodialysis
JID - 101093910
SB  - IM
MH  - Aged
MH  - Capsule Endoscopy/*methods
MH  - Female
MH  - Gastrointestinal Hemorrhage/*etiology/pathology
MH  - Humans
MH  - Intestine, Small/*pathology
MH  - Male
MH  - Renal Dialysis/*adverse effects/methods
OTO - NOTNLM
OT  - Small intestine
OT  - capsule endoscopy
OT  - dialysis patients
OT  - gastrointestinal hemorrhage
OT  - renal failure
EDAT- 2018/09/22 06:00
MHDA- 2020/06/11 06:00
CRDT- 2018/09/22 06:00
PHST- 2018/01/24 00:00 [received]
PHST- 2018/05/15 00:00 [revised]
PHST- 2018/09/22 06:00 [pubmed]
PHST- 2020/06/11 06:00 [medline]
PHST- 2018/09/22 06:00 [entrez]
AID - 10.1111/hdi.12683 [doi]
PST - ppublish
SO  - Hemodial Int. 2019 Jan;23(1):77-80. doi: 10.1111/hdi.12683. Epub 2018 Sep 20.