PMID- 30242982 OWN - NLM STAT- MEDLINE DCOM- 20190510 LR - 20190510 IS - 1755-3768 (Electronic) IS - 1755-375X (Linking) VI - 97 IP - 4 DP - 2019 Jun TI - The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies. PG - 364-371 LID - 10.1111/aos.13883 [doi] AB - PURPOSE: The aim of the European Eye Epidemiology (E3) consortium was to develop a spectral-domain optical coherence tomography (SD-OCT)-based classification for macular diseases to standardize epidemiological studies. METHODS: A European panel of vitreoretinal disease experts and epidemiologists belonging to the E3 consortium was assembled to define a classification for SD-OCT imaging of the macula. A series of meeting was organized, to develop, test and finalize the classification. First, grading methods used by the different research groups were presented and discussed, and a first version of classification was proposed. This first version was then tested on a set of 50 SD-OCT images in the Bordeaux and Rotterdam centres. Agreements were analysed and discussed with the panel of experts and a final version of the classification was produced. RESULTS: Definitions and classifications are proposed for the structure assessment of the vitreomacular interface (visibility of vitreous interface, vitreomacular adhesion, vitreomacular traction, epiretinal membrane, full-thickness macular hole, lamellar macular hole, macular pseudo-hole) and of the retina (retinoschisis, drusen, pigment epithelium detachment, hyper-reflective clumps, retinal pigment epithelium atrophy, intraretinal cystoid spaces, intraretinal tubular changes, subretinal fluid, subretinal material). Classifications according to size and location are defined. Illustrations of each item are provided, as well as the grading form. CONCLUSION: The E3 SD-OCT classification has been developed to harmonize epidemiological studies. This homogenization will allow comparing and sharing data collection between European and international studies. CI - (c) 2018 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. FAU - Gattoussi, Sarra AU - Gattoussi S AD - Bordeaux Population Health Research Center, Team LEHA, UMR 1219, Inserm, University of Bordeaux, Bordeaux, France. AD - Service d'Ophtalmologie, CHU de Bordeaux, Bordeaux, France. FAU - Buitendijk, Gabrielle H S AU - Buitendijk GHS AD - Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands. AD - Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands. FAU - Peto, Tunde AU - Peto T AUID- ORCID: 0000-0001-6265-0381 AD - School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast, UK. FAU - Leung, Irene AU - Leung I AD - Department of Research and Development, Moorfields Eye Hospital NHS Foundation Trust, London, UK. FAU - Schmitz-Valckenberg, Steffen AU - Schmitz-Valckenberg S AD - GRADE Reading Center, Department of Ophthalmology, University of Bonn, Bonn, Germany. FAU - Oishi, Akio AU - Oishi A AD - Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. FAU - Wolf, Sebastian AU - Wolf S AD - Bern Photographic Reading Center, Department of Ophthalmology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland. FAU - Deak, Gabor AU - Deak G AD - Vienna Reading Center, Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. FAU - Delcourt, Cecile AU - Delcourt C AUID- ORCID: 0000-0002-2099-0481 AD - Bordeaux Population Health Research Center, Team LEHA, UMR 1219, Inserm, University of Bordeaux, Bordeaux, France. FAU - Klaver, Caroline C W AU - Klaver CCW AD - Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands. AD - Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands. FAU - Korobelnik, Jean-Francois AU - Korobelnik JF AD - Bordeaux Population Health Research Center, Team LEHA, UMR 1219, Inserm, University of Bordeaux, Bordeaux, France. AD - Service d'Ophtalmologie, CHU de Bordeaux, Bordeaux, France. CN - European Eye Epidemiology (E3) consortium LA - eng GR - Carl Zeiss Meditec AG/ GR - Laboratoires Thea/ GR - Novartis/ GR - OOgroup/ PT - Journal Article PT - Multicenter Study DEP - 20180922 PL - England TA - Acta Ophthalmol JT - Acta ophthalmologica JID - 101468102 SB - IM MH - Aged MH - *Epidemiologic Studies MH - Europe/epidemiology MH - Female MH - Humans MH - Macula Lutea/*pathology MH - Male MH - Middle Aged MH - Morbidity MH - Retinal Diseases/*classification/diagnosis/epidemiology MH - Severity of Illness Index MH - Tomography, Optical Coherence/*methods OTO - NOTNLM OT - epidemiology OT - macular degeneration OT - optical coherence tomography OT - retina OT - vitreous FIR - Acar, Niyazi IR - Acar N FIR - Anastosopoulos, Eleftherios IR - Anastosopoulos E FIR - Azuara-Blanco, Augusto IR - Azuara-Blanco A FIR - Berendschot, Tos IR - Berendschot T FIR - Bergen, Arthur IR - Bergen A FIR - Bertelsen, Geir IR - Bertelsen G FIR - Binquet, Christine IR - Binquet C FIR - Bird, Alan IR - Bird A FIR - Bobak, Martin IR - Bobak M FIR - Bogelund Larsen, Morten IR - Bogelund Larsen M FIR - Boon, Camiel IR - Boon C FIR - Bourne, Rupert IR - Bourne R FIR - Bretillon, Lionel IR - Bretillon L FIR - Broe, Rebecca IR - Broe R FIR - Bron, Alain IR - Bron A FIR - Cachulo, Maria Luz IR - Cachulo ML FIR - Capuano, Vittorio IR - Capuano V FIR - Carriere, Isabelle IR - Carriere I FIR - Chakravarthy, Usha IR - Chakravarthy U FIR - Chan, Michelle IR - Chan M FIR - Chang, Petrus IR - Chang P FIR - Colijn, Johanna IR - Colijn J FIR - Cougnard-Gregoire, Audrey IR - Cougnard-Gregoire A FIR - Cree, Angela IR - Cree A FIR - Creuzot-Garcher, Catherine IR - Creuzot-Garcher C FIR - Cumberland, Phillippa IR - Cumberland P FIR - Cunha-Vaz, Jose IR - Cunha-Vaz J FIR - Daien, Vincent IR - Daien V FIR - De Jong, Eiko IR - De Jong E FIR - Deak, Gabor IR - Deak G FIR - Delyfer, Marie-Noelle IR - Delyfer MN FIR - den Hollander, Anneke IR - den Hollander A FIR - Dietzel, Martha IR - Dietzel M FIR - Erke, Maja Gran IR - Erke MG FIR - Faria, Pedro IR - Faria P FIR - Farinha, Claudia IR - Farinha C FIR - Fauser, Sascha IR - Fauser S FIR - Finger, Robert IR - Finger R FIR - Fletcher, Astrid IR - Fletcher A FIR - Foster, Paul IR - Foster P FIR - Founti, Panayiota IR - Founti P FIR - Gorgels, Theo IR - Gorgels T FIR - Grauslund, Jakob IR - Grauslund J FIR - Grus, Franz IR - Grus F FIR - Hammond, Christopher IR - Hammond C FIR - Helmer, Catherine IR - Helmer C FIR - Hense, Hans-Werner IR - Hense HW FIR - Hermann, Manuel IR - Hermann M FIR - Hoehn, Rene IR - Hoehn R FIR - Hogg, Ruth IR - Hogg R FIR - Holz, Frank IR - Holz F FIR - Hoyng, Carel IR - Hoyng C FIR - Jansonius, Nomdo IR - Jansonius N FIR - Janssen, Sarah IR - Janssen S FIR - Kersten, Eveline IR - Kersten E FIR - Khawaja, Anthony IR - Khawaja A FIR - Lamparter, Julia IR - Lamparter J FIR - Le Goff, Melanie IR - Le Goff M FIR - Lechanteur, Yara IR - Lechanteur Y FIR - Lehtimaki, Terho IR - Lehtimaki T FIR - Mauschitz, Matthias IR - Mauschitz M FIR - Meester, Magda IR - Meester M FIR - Merle, Benedicte IR - Merle B FIR - Meyer Zu Westrup, Verena IR - Meyer Zu Westrup V FIR - Midena, Edoardo IR - Midena E FIR - Miotto, Stefania IR - Miotto S FIR - Mirshahi, Alireza IR - Mirshahi A FIR - Mohan-Said, Sadek IR - Mohan-Said S FIR - Mueller, Michael IR - Mueller M FIR - Muldrew, Alyson IR - Muldrew A FIR - Murta, Joaquim IR - Murta J FIR - Nickels, Stefan IR - Nickels S FIR - Nunes, Sandrina IR - Nunes S FIR - Owen, Christopher IR - Owen C FIR - Pfeiffer, Norbert IR - Pfeiffer N FIR - Piermarocchi, Stefano IR - Piermarocchi S FIR - Prokofyeva, Elena IR - Prokofyeva E FIR - Rahi, Jugnoo IR - Rahi J FIR - Raitakari, Olli IR - Raitakari O FIR - Rauscher, Franziska IR - Rauscher F FIR - Ribeiro, Luisa IR - Ribeiro L FIR - Rougier, Marie-Benedicte IR - Rougier MB FIR - Rudnicka, Alicja IR - Rudnicka A FIR - Sahel, Jose IR - Sahel J FIR - Salonikiou, Aggeliki IR - Salonikiou A FIR - Sanchez, Clarisa IR - Sanchez C FIR - Schuster, Alexander IR - Schuster A FIR - Schweitzer, Cedric IR - Schweitzer C FIR - Segato, Tatiana IR - Segato T FIR - Shehata, Jasmin IR - Shehata J FIR - Silva, Rufino IR - Silva R FIR - Silvestri, Giuliana IR - Silvestri G FIR - Simader, Christian IR - Simader C FIR - Souied, Eric IR - Souied E FIR - Speckauskas, Martynas IR - Speckauskas M FIR - Springelkamp, Henriet IR - Springelkamp H FIR - Tapp, Robyn IR - Tapp R FIR - Topouzis, Fotis IR - Topouzis F FIR - van Leeuwen, Elisa IR - van Leeuwen E FIR - Verhoeven, Virginie IR - Verhoeven V FIR - Verzijden, Timo IR - Verzijden T FIR - Von Hanno, Therese IR - Von Hanno T FIR - Wiedemann, Peter IR - Wiedemann P FIR - Williams, Katie IR - Williams K FIR - Wolfram, Christian IR - Wolfram C FIR - Yip, Jennifer IR - Yip J FIR - Zerbib, Jennyfer IR - Zerbib J EDAT- 2018/09/23 06:00 MHDA- 2019/05/11 06:00 CRDT- 2018/09/23 06:00 PHST- 2017/11/13 00:00 [received] PHST- 2018/06/24 00:00 [accepted] PHST- 2018/09/23 06:00 [pubmed] PHST- 2019/05/11 06:00 [medline] PHST- 2018/09/23 06:00 [entrez] AID - 10.1111/aos.13883 [doi] PST - ppublish SO - Acta Ophthalmol. 2019 Jun;97(4):364-371. doi: 10.1111/aos.13883. Epub 2018 Sep 22.