PMID- 30248826
OWN - NLM
STAT- MEDLINE
DCOM- 20181221
LR  - 20181221
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 645
DP  - 2018 Dec 15
TI  - Short-term effects of ambient air pollution exposure on lung function: A 
      longitudinal study among healthy primary school children in China.
PG  - 1014-1020
LID - S0048-9697(18)32640-8 [pii]
LID - 10.1016/j.scitotenv.2018.07.154 [doi]
AB  - BACKGROUND: Short-term exposure to ambient air pollution has been associated with 
      reduced lung function among asthmatic children. However, there is little 
      information about the effects among healthy children, especially in areas with 
      relatively high exposure background. OBJECTIVE: To examine the association 
      between short-term effects of ambient air pollutants and lung function among 
      healthy primary school-aged children in China. METHODS: A total of 334 healthy 
      children (7-11 years) from four cities (Chengdu (Southwest China), Guangzhou 
      (Southern China), Wuhan (Central China), and Xi'an (Northwest China)) in China 
      with repeated lung function measurement in 2014-2016 were included. Daily ambient 
      concentrations of PM(2.5), PM(10), NO(2), SO(2), mean temperature, and relative 
      humidity data were obtained. Linear mixed model was used to estimate the percent 
      change in lung function associated with per inter-quartile range (IQR) exposure 
      (up to 3 days) increase after adjusting for confounders. RESULTS: Ambient PM(2.5) 
      and PM(10) exposure were associated with decrements in lung function 
      measurements. The moving average exposures generally showed stronger effect 
      estimates than the single lag day exposures. An IQR increase in two-day average 
      (lag01 day) PM(10) exposure (IQR, 144 mug/m(3)) was significantly associated with 
      2.56% decrease in FVC, 5.46% in FEV(1), 4.23% in PEF, and 7.35% in FEF(25%), 
      respectively. The effect estimates were stronger after adjusting for gaseous 
      pollutants in particulate matter (PM) models. The strengths of these associations 
      were stronger in girls than those in boys. CONCLUSION: Short-term exposure to PM 
      was associated with reduced lung function in healthy children. The estimated 
      adverse effects were greater in girls than in boys.
CI  - Copyright (c) 2018. Published by Elsevier B.V.
FAU - Chen, Chen
AU  - Chen C
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Li, Chengcheng
AU  - Li C
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Li, Yawei
AU  - Li Y
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Liu, Jingyi
AU  - Liu J
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Meng, Congshen
AU  - Meng C
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Han, Jingxiu
AU  - Han J
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China.
FAU - Zhang, Yawei
AU  - Zhang Y
AD  - Department of Environmental Health Science, Yale School of Public Health 
      Sciences, New Haven 06511, USA.
FAU - Xu, Dongqun
AU  - Xu D
AD  - National Institute of Environmental and Health, Chinese Center for Disease 
      Control and Prevention, Beijing 100050, China. Electronic address: 
      xudq@chinacdc.cn.
LA  - eng
PT  - Journal Article
DEP - 20180720
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Air Pollutants)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - Air Pollutants/*analysis
MH  - Air Pollution/*statistics & numerical data
MH  - Child
MH  - China/epidemiology
MH  - Cities
MH  - Environmental Exposure/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Particulate Matter
MH  - Respiratory Function Tests
MH  - Respiratory Tract Diseases/epidemiology
OTO - NOTNLM
OT  - Air pollution
OT  - Children
OT  - Lung function
OT  - Repeated measures
OT  - Short-term
EDAT- 2018/09/27 06:00
MHDA- 2018/12/24 06:00
CRDT- 2018/09/26 06:00
PHST- 2018/04/04 00:00 [received]
PHST- 2018/07/02 00:00 [revised]
PHST- 2018/07/12 00:00 [accepted]
PHST- 2018/09/26 06:00 [entrez]
PHST- 2018/09/27 06:00 [pubmed]
PHST- 2018/12/24 06:00 [medline]
AID - S0048-9697(18)32640-8 [pii]
AID - 10.1016/j.scitotenv.2018.07.154 [doi]
PST - ppublish
SO  - Sci Total Environ. 2018 Dec 15;645:1014-1020. doi: 
      10.1016/j.scitotenv.2018.07.154. Epub 2018 Jul 20.